Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
461 Results for "
O2
" in MedChemExpress (MCE) Product Catalog:
Products (461)
461 Results for "O2" in MCE Product Catalog:
製品番号: HY-D3143
CAS 番号: 2411524-33-7
製品番号: HY-120485
CAS 番号: 128232-14-4
別名: IRFI-016
研究分野:
Raxofelast (IRFI-016) is an antioxidant agent in various models of ischemia-reperfusion injury. Raxofelast has antiproliferative activity in H2O2-stimulated rat aortic smooth muscle cells. Raxofelast attenuates the activation of mitogen-activating protein kinase (MAPK), ERK kinase 1, 2 (MEK1,2) and protein kinase C (PKC) without affecting Ras expression .
製品番号: HY-N2410R
CAS 番号: 66648-43-9
別名: N-feruloyltyramine (Standard); Moupinamide (Standard)
製品番号: HY-157437
CAS 番号: 3038810-09-9
AChE/BChE-IN-16 (compound C7) is a potent cholinesterase (ChE) inhibitor with IC50s of 30 nM and 48 nM for human acetylcholinesterase (hAChE) and human butyrylcholinesterase (hBChE), respectively. AChE/BChE-IN-16 exhibits a remarkable capacity to safeguard PC12 cells against H2O2-induced apoptosis and effectively suppresses the production of reactive oxygen species (ROS) .
製品番号: HY-121174
CAS 番号: 39723-40-5
別名: Catharticin
製品番号: HY-125859E
Target:
Myeloperoxidase, Human Neutrophil is a peroxidase. Myeloperoxidase, Human Neutrophil is a potent antibacterial agent by catalyzing the H2O2-dependent oxidation of chloride anion to generate hypochlorous acid. Myeloperoxidase, Human Neutrophil catalyzes the degradation of N-retinyl-idene-N-retinylethanolamine, a toxic form of retinal lipofuscin. Myeloperoxidase, Human Neutrophil also triggers lysosomal stress and cell death. Myeloperoxidase, Human Neutrophil can be used for the researches of inflammation and infection .
製品番号: HY-159560
Target:
研究分野:
PBA-AMF can be activated by H2O2 to release Amonafide (AMF) (HY-10982). PBA-AMF selectively inhibited the proliferation of breast cancer cells, while sparing non-cancerous cells. PBA-AMF inhibits tumor proliferation by inhibiting DNA synthesis, reducing ATP levels, inducing apoptosis, and arresting the cell cycle. PBA-AMF can be used for research of tumors and other diseases associated with increased H2O2 levels .
製品番号: HY-W130303
CAS 番号: 625-77-4
別名: N-Acetylacetamide; Diacetylamine; Diacetimide
Target:
研究分野:
Diacetamide is shown to form a variety of new compounds with a general formula [M(C4H7O2N) 3](ClO4)2, where M = Mn(II), Fe(II), Co(II), Ni(II), or Zn(II). Diacetamide ligands can be used in uranium extraction from wastewater. Diacetamide can be used for amidase synthesis [2] .
製品番号: HY-N2442
CAS 番号: 74805-89-3
Target:
製品番号: HY-15923
CAS 番号: 82692-97-5
製品番号: HY-W018801
CAS 番号: 607-32-9
Target:
研究分野:
5-Nitroisoquinoline (5NIQ) has the molecular formula C9H6N2O2 and can be used as a molecular building block .
製品番号: HY-108351R
CAS 番号: 861891-50-1
Target:
研究分野:
IM-54 (Standard) is the analytical standard of IM-54 (HY-108351). This product is intended for research and analytical applications. IM-54 is a selective inhibitor of oxidative stress-induced necrosis. IM-54 shows potent inhibitory activity against H2O2-induced necrosis. IM-54 acts as a potential cardioprotective agent and biological tool for investigating the molecular mechanisms of cell death [2].
製品番号: HY-109804R
CAS 番号: 1001015-18-4
CORM-401 (Standard) is the analytical standard of CORM-401 (HY-109804). This product is intended for research and analytical applications. CORM-401 is an oxidant-sensitive CO-releasing molecule. CORM-401 induces NO increase in the regulation of endothelial calcium signalling. CORM-401 reduces TNF-α/CHX and H2O2-induced ROS production. CORM-401 uncouples mitochondrial respiration and inhibits glycolysis [2] .
製品番号: HY-N13174
CAS 番号: 1802175-67-2
Category:
製品番号: HY-146172
CAS 番号: 2710376-48-8
Antioxidant agent-3 (Compound 14q), an potent antioxidant, displays potent DPPH radicals scavenging activity and ABTS + scavenging activity with IC50s of 26.58 and 30.31 μM, respectively. Antioxidant agent-3 (Compound 14q) increases reactive oxygen species (ROS), superoxide dismutase (SOD) and glutathione (GSH), and reduced lactate dehydrogenase (LDH) in H2O2-treated HepG2 cells .
製品番号: HY-178141
研究分野:
AChE/BuChE-IN-7 is a dual-action inhibitor with an IC50 valueof 0.15 μM for AChE and 0.7 μM for BuChE, SI of 4.7. AChE/BuChE-IN-7 shows anti-oxidant activity and can mitigate H2O2-induced cytotoxicity. AChE/BuChE-IN-7 has genomic stability and prolonged systemic availability. AChE/BuChE-IN-7 can be used for the research of neurological disease, such as Alzheimer's disease .
製品番号: HY-N7697E
CAS 番号: 117436-78-9
Target:
製品番号: HY-W927359
CAS 番号: 109653-47-6
製品番号: HY-172604
研究分野:
Neuroprotective agent 10 is an orally active, blood-brain barrier permeable neuroprotective agent. Neuroprotective agent 10 scavenges ABTS, DPPH and superoxide anion free radicals. Neuroprotective agent 10 inhibits abnormal electrical discharges. At the cellular level, Neuroprotective agent 10 alleviates H2O2-induced oxidative damage and LPS (HY-D1056)-induced neuroinflammation, and relieves epileptic symptoms and oxidative damage in mice. Neuroprotective agent 10 can be used in the research of epilepsy .
製品番号: HY-124834
CAS 番号: 75483-04-4
Target:
研究分野:
Nrf2 activator-10 (Compound AI-1) is a PI3K-dependent inducer for antioxidant response element (ARE) (EC50 is 2.7 μM) and an activator for Nrf2. Nrf2 activator-10 modifies Keap1, blocks Cul3-Keap1 ubiquitin ligase complex, activates the transcription of Nrf2. Nrf2 activator-10 protects cells from H2O2-induced apoptosis.
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
