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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
469 Results for "
O2
" in MedChemExpress (MCE) Product Catalog:
Products (469)
469 Results for "O2" in MCE Product Catalog:
Referencia número: HY-149422
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Áreas de investigación:
NIR-FP is a near-infrared fluorescent probe with high sensitivity and selectivity for superoxide anion O 2-. O 2- is the main precursor of ROS, and ferroptosis-mediated epilepsy models can be dynamically tracked by detecting O 2-. Ferroptosis-mediated epilepsy models include: kainic acid (HY-N2309)-induced chronic epilepsy model, Pentylenetetrazole-induced acute epilepsy model, and pilocarpine (HY-B0726A)-induced epilepsy model .
Referencia número: HY-N15756
No. CAS: 240131-71-9
Category:
Alkaloids Plant Sinomenium acutum (Thunb.) Rehd. et Wils. Extract Other Alkaloids Menispermaceae Extract
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Referencia número: HY-N4278
No. CAS: 1026020-27-8
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Huangjiangsu A, pseudoprotodioscin, methyl protobioside, protodioscin, and protodeltonin, isolated from D. villosa.
Huangjiangsu A has hepatoprotective potential against H2O2-induced cytotoxicity and ROS generation and could be promising as potential therapeutic agents for liver diseases .
Referencia número: HY-N5045
No. CAS: 120444-60-2
Category:
Plant Simple Phenylpropanols Scrophulariaceae Extract Phenols Polyphenols Rehmannia glutinosa (Gaert.) Libosch. ex Fisch. et Mey Extract Phenylpropanoids Disease Research Fields Inflammation/Immunology
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Referencia número: HY-P5316
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Referencia número: HY-P5318
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Referencia número: HY-P5317
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Referencia número: HY-D2963
Referencia número: HY-111505A
No. CAS: 2416146-10-4
NAcM-OPT (hydrochloride) is a protein interaction inhibitor. NAcM-OPT (hydrochloride) can disrupt the interaction between DCN1 and UBC12, with an IC50 value of 80 nM. NAcM-OPT (hydrochloride) can protect keratinocytes from H2O2-induced cell damage by promoting autophagy [2].
Referencia número: HY-149094
No. CAS: 2344786-13-4
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Áreas de investigación:
Neuroprotective agent 1 (2), a promising neuroprotective agent for the study of ischemic stroke, shows promising neuroprotective activity with the EC50 value of 16.07 μM in the model of glutamate-induced excitotoxicity and 19.30 μM in the model of H2O2-induced oxidative damage .
Referencia número: HY-P5316A
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Referencia número: HY-P5318A
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Synonyms: RG6042; IONIS-HTTRx
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Áreas de investigación:
Tominersen (RG6042) is a second-generation 2′-O-(2-methoxyethyl) antisense oligonucleotide that targets huntingtin protein (HTT) mRNA and potently suppresses HTT production. Tominersen improves survival and reduces brain atrophy in mice. Tominersen can be used for the research of Huntington’s disease (HD) [2].
Referencia número: HY-132579A
Pureza: 97.36%
Synonyms: RG6042 sodium; IONIS-HTTRx sodium
Target:
Áreas de investigación:
Tominersen sodium (RG6042) is a second-generation 2′-O-(2-methoxyethyl) antisense oligonucleotide that targets huntingtin protein (HTT) mRNA and potently suppresses HTT production. Tominersen sodium improves survival and reduces brain atrophy in mice. Tominersen sodium can be used for the research of Huntington’s disease (HD) [2].
Referencia número: HY-155022
No. CAS: 2937454-22-1
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AChE-IN-30 is an AChE inhibitor with an IC50 value of 4.4 μM. AChE-IN-30 has neuroprotective activity, and inhibits H2O2-induced apoptosis by suppressing intracellular ROS accumulation. AChE-IN-30 can be used for research of Alzheimer's disease .
Referencia número: HY-N2410
No. CAS: 66648-43-9
Synonyms: N-feruloyltyramine; Moupinamide
Referencia número: HY-P5317A
Áreas de investigación:
Referencia número: HY-183801
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Áreas de investigación:
Cu2LCl2(H2O) acts as a proteasome inhibitor and protein tyrosine phosphatase inhibitor, with antiproliferative and apoptosis-inducing effects. Cu2LCl2(H2O) exhibits low cytotoxicity against normal cells and remarkable in vivo antitumor efficacy. Cu2LCl2(H2O) inhibits proteasome activity in colon cancer cells, and suppresses PTP1B and TCPTP activities in breast cancer cells. Cu2LCl2(H2O) can be used in the research of colon cancer, breast cancer and liver cancer .
Referencia número: HY-146168
No. CAS: 1012860-13-7
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Nrf2 activator-5 (compound 1) is a potent Nrf2 activator that can attenuate H2O2-induced oxidative stress and LPS-stimulated inflammation in BV-2 microglial cells. Nrf2 activator-5 exhibits antioxidant and anti-inflammatory activities .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
