24 Results for "

Dehydrogenation

" in MedChemExpress (MCE) Product Catalog:
Products (24)

24 Results for "Dehydrogenation" in MCE Product Catalog:

188
188 Publications Verification
製品番号: HY-D0079
CAS 番号: 104821-25-2
別名: Hydroethidine; PD-MY 003
Dihydroethidium, also known as DHE, is a peroxide indicator. Dihydroethidium penetrates cell membranes to form a fluorescent protein complex with blue fluoresces. After entering the cells, Dihydroethidium is mainly localized in the cell membrane, cytoplasm and nucleus, and the staining effect is the strongest in the nucleus. Dihydroethidium produces inherent blue fluorescence with a maximum excitation wavelength of 370 nm and a maximum emission wavelength of 420 nm; after dehydrogenation, Dihydroethidium combines with RNA or DNA to produce red fluorescence with a maximum excitation wavelength of 300 nm and a maximum emission wavelength of 610 nm. 535 nm can also be used as the excitation wavelength for actual observation .
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製品番号: HY-N4067
CAS 番号: 566-24-5
別名: isoCDCA
Category:  

天然物

Isochenodeoxycholic acid (isoCDCA) is a FXR agonist. Isochenodeoxycholic acid activates the activity of FXR and induces the mRNA expression of FXR target genes (Ostβ and Kng1). Isochenodeoxycholic acid serves as a substrate for the liver class I ADH γγ isozyme-mediated 3β-dehydrogenation reaction .
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製品番号: HY-P3186A
CAS 番号: 9028-53-9
別名: GDH-NAD
研究分野:  

Metabolic Disease

NAD-dependent glucose dehydrogenase (GDH-NAD) is an oxidoreductase that uses NAD + as a coenzyme, specifically catalyzes the dehydrogenation of glucose to gluconolactone, and reduces NAD + to NADH. NAD-dependent glucose dehydrogenase exhibits favorable substrate selectivity and stability, and is not affected by oxygen .
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製品番号: HY-N4031
CAS 番号: 82375-29-9
Humantenine is a highly toxic indole alkaloid from Gelsemium elegans (Gardn. & Champ.) Benth. that binds to RNA m6A modification regulatory proteins (ALKBH5, METTL). Humantenine stably binds via hydrogen bonding and hydrophobic interactions and disrupts the m6A methylation level of target genes, thereby impairing the expression of intestinal epithelial cell tight junction and cytoskeleton-related genes, causing intestinal barrier dysfunction and significant intestinal cytotoxicity. The intraperitoneal injection LD50 values of Humantenine are <1 mg/kg in mice, 1.2 mg/kg in male rats and 1.5 mg/kg in female rats, respectively. Species differences exist in the metabolism of Humantenine in human, porcine, goat and rat liver microsomes, and demethylation, dehydrogenation and oxidation occur in liver microsomes .
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製品番号: HY-118614
CAS 番号: 487-19-4
純度:  99.35%
Target:  

Drug Metabolite

研究分野:  

Neurological Disease

β-Nicotyrine is a metabolite of Nicotine.β-Nicotyrine, isolated from the leaves of Nicotiana tabacum plants and from cigarette smoke condensate, is a minor tobacco alkaloid .
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製品番号: HY-DY1015
CAS 番号: 104821-25-2
Dihydroethidium (solution) , also known as DHE, is a peroxide indicator. Dihydroethidium penetrates cell membranes to form a fluorescent protein complex with blue fluoresces. After entering the cells, Dihydroethidium is mainly localized in the cell membrane, cytoplasm and nucleus, and the staining effect is the strongest in the nucleus. Dihydroethidium produces inherent blue fluorescence with a maximum excitation wavelength of 370 nm and a maximum emission wavelength of 420 nm; after dehydrogenation, Dihydroethidium combines with RNA or DNA to produce red fluorescence with a maximum excitation wavelength of 300 nm and a maximum emission wavelength of 610 nm. 535 nm can also be used as the excitation wavelength for actual observation .
Solvent and concentration: DMSO: 5 mM
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製品番号: HY-W015003
CAS 番号: 86-28-2
別名: N-Ethylcarbazole
研究分野:  

Others

9-Ethylcarbazole (N-Ethylcarbazole) serves as a hydrogen storage material. The introduction of nitrogen (N) into 9-ethylcarbazole can reduce the endothermic nature of the reaction and decrease the dehydrogenation temperature, thereby facilitating the process of hydrogen storage and release .
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製品番号: HY-W010283
CAS 番号: 91-55-4
研究分野:  

Others

2,3-Dimethylindol is an organic liquid hydrogen carrier (LOHC). 2,3-Dimethylindol enables reversible hydrogen storage and release via catalytic hydrogenation/dehydrogenation reactions. 2,3-Dimethylindol is promising for research of clean energy storage .
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製品番号: HY-W102516
CAS 番号: 1162-56-7
別名: Δ6-Progesterone
6-Dehydroprogesterone (Δ6-Progesterone) is a steroid compound that can be found in Botryodiplodia theobromae. 6-Dehydroprogesterone is a metabolic product of Progesterone (HY-N0437) after a microbial dehydrogenation reaction. 6-Dehydroprogesterone can be used to study steroid metabolism pathways, microbial dehydrogenase activity, and the biotransformation of steroids .
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製品番号: HY-N7372
CAS 番号: 66067-26-3
Licoisoflavanone is an orally active isoflavane-based immunomodulator with multiple activities including antiviral, anti-inflammatory, cytoprotective and cancer cell apoptosis-inducing effects. Licoisoflavanone can be isolated from the roots and rhizomes of Glycyrrhiza uralensis Fisch. Licoisoflavanone not only enhances the body's immunity, but also effectively prevents acute respiratory distress syndrome and multiple organ damage by alleviating cytokine storm, thereby reducing the degree of inflammation. In rats, Licoisoflavanone undergoes multiple metabolic transformation processes such as glucuronidation, hydroxylation, sulfation, methylation and dehydrogenation. Licoisoflavanone has become an important candidate molecule for research on COVID-19 and related inflammatory diseases .
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製品番号: HY-125863B
CAS 番号: 9001-40-5
別名: G6PD (yeast, recombinant)
Glucose 6-phosphate dehydrogenase (yeast, recombinant) (G6PD (yeast, recombinant)) is a recombinant enzyme requiring NADP + as a coenzyme. Glucose 6-phosphate dehydrogenase (yeast, recombinant) catalyzes the oxidative dehydrogenation of glucose-6-phosphate to form 6-phosphoglucono-δ-lactone, as well as the reduction of NADP + to NADPH. Glucose 6-phosphate dehydrogenase (yeast, recombinant) relies on the amino acid Arg-52 to bind NADP +. Glucose 6-phosphate dehydrogenase (yeast, recombinant) undergoes competitive inhibition by NADPH and strong inhibition by zinc ions (Zn 2+). Glucose 6-phosphate dehydrogenase (yeast, recombinant) is an enzyme in the pentose phosphate pathway, which is one of the glucose metabolic pathways. Glucose 6-phosphate dehydrogenase (yeast, recombinant) can be used for the quantitative detection of ATP, glucose and creatine kinase .
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製品番号: HY-P10563
CAS 番号: 2580150-96-3
別名: BHV-1100
Target:  

CD38 IFNAR

研究分野:  

Cancer

Noraramtide (BHV-1100) is an antibody-recruiting molecule. Noraramtide binds to CD38 and recruits natural killer (NK) cells to mediate antibody-dependent cellular cytotoxicity. Noraramtide enhances the capacity of autologous cytokine-induced memory-like (CIML) NK cells to produce IFNγ and CD107a, thereby improving their cytotoxicity against multiple myeloma cells. Noraramtide can be used in the research of multiple myeloma .
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製品番号: HY-W587751
CAS 番号: 125184-95-4
別名: Amorpha-4,11-diene-12-ol
Target:  

Drug Intermediate

研究分野:  

Infection

Arteannuic alcohol (Amorpha-4,11-diene-12-ol) is a precursor substance in the biosynthetic pathway of Artemisinin (HY-B0094). Alcohol dehydrogenase catalyzes the dehydrogenation reaction of chlorogenic alcohol to produce artemisinic aldehyde .
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製品番号: HY-P3820
[Dehydro-Pro4] Substance P (4-11) is a peptide fragment of Substance P. Substance P is a peptide mainly secreted by neurons. Substance P takes part in many biological processes, including nociception, inflammation and immunity .
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製品番号: HY-E70239
CAS 番号: 6712-02-3
Target:  

Endogenous Metabolite

研究分野:  

Others

2-Methylbutyryl-CoA is a branched-chain acyl-CoA substrate. It serves as the preferred substrate for potato 2-methylbutyryl-CoA dehydrogenase (2MBCD), which catalyzes its α,β-dehydrogenation .
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製品番号: HY-N2561
CAS 番号: 38710-26-8
Seneciphylline N-Oxide is a dehydrogenation product of Senecionine N-oxide. Seneciphylline N-Oxide is a natural compound isolated from root cultures of Senecio erucifolius (Asteraceae) .
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製品番号: HY-W034154
CAS 番号: 19529-00-1
別名: Tetrakis(triphenylphosphine)ruthenium dihydride
Dihydridotetrakis(triphenylphosphine)ruthenium(II) (Tetrakis(triphenylphosphine)ruthenium dihydride) is a catalyst with good catalytic activity. Dihydridotetrakis(triphenylphosphine)ruthenium(II) can be used in organic synthesis reactions, especially in hydrogenation and dehydrogenation reactions. Dihydridotetrakis(triphenylphosphine)ruthenium(II) has received extensive attention in the study of metal catalysts, and its high efficiency makes it an ideal research object.
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製品番号: HY-W653739
CAS 番号: 41944-86-9
別名: Abscisic aldehyde
Target:  

Drug Intermediate

研究分野:  

Others

(+)-Abscisic Aldehyde (ABAld) is an intermediate in the biosynthesis of the plant hormone abscisic acid (ABA). (+)-Abscisic Aldehyde is produced by the dehydrogenation of xanthoxin by xanthoxin dehydrogenases, followed by selective oxidation by abscisic aldehyde oxygenase. (+)-Abscisic Aldehyde has an oxidizing PsAOγ activity and it correlates with ABA accumulation in the old leaves of pea plants with long exposure of salinity, ammonium or nitrogen deficiency. (+)-Abscisic Aldehyde can be used for plant growth and development research .
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製品番号: HY-E71471
研究分野:  

Others

2-Amino-4-deoxychorismate dehydrogenase (EC 2.6.1.86) is an oxidoreductase that catalyzes the dehydrogenation of 2-amino-4-deoxychorismate (ADC).
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製品番号: HY-E71583
研究分野:  

Others

2-Methyl-1-pyrroline reductase (EC 1.5.1.48) is a spermidine dehydrogenase belonging to the class of oxidoreductases; it catalyzes the oxidative dehydrogenation of spermidine and is involved in polyamine metabolism.
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