STK189682
STK189682 is an ATPase inhibitor targeting MDA5, LGP2 and DDX1, with IC50 values of 7 μM, 7 μM and 5 μM, respectively. STK189682 binds to the MDA5-ATP complex in an ATP-noncompetitive manner and does not compete with RNA.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 765922-18-7
- 分子式: C21H16N4O4S2
- 分子量:452.51
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
DNA/RNA Synthesis アイソフォーム固有の製品をすべて表示
More
生物活性
STK189682 potently inhibits the ATPase activities of recombinant MDA5 (IC50 = 7 μM), LGP2 (IC50 = 7 μM) and DDX1 (IC50 = 5 μM)[1].
STK189682 is an ATP-uncompetitive inhibitor of recombinant MDA5, which is evidenced by the observation that its IC50 value decreases as ATP concentration increases[1].
STK189682 does not compete with RNA for binding to recombinant MDA5, as the IC50 value remains unchanged with increasing RNA concentrations[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
CAS 番号 765922-18-7
-
分子量 452.51
-
分子式 C21H16N4O4S2
-
SMILES
O=C(C1=CC=C(NC2=NC(C3=C(C)N=C(NC(C4=CC=CC=C4)=O)S3)=CS2)C=C1O)O
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
STK189682 関連分類
HY-187308 関連分類
Powered by Bioz