19(S)-HETE
19(S)-HETE is an arachidonic acid metabolite produced by cytochrome P450 enzymes. 19(S)-HETE is a full orthosteric agonist of the prostacyclin (IP) receptor with an EC50 value of 567 nM. 19(S)-HETE inhibits platelet activation and relaxation of vessels.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 115461-40-0
- 화학식: C20H32O3
- 분자량:320.47
-
보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- 순도&문서
- References
-
Help & FAQs
-
HY-130309
(±)8(9)-EpETE
-
HY-130140
8,9-DiHETE
-
HY-130138C
5,6-DiHETE
-
HY-121758
2-Hydroxyicosanoic acid
-
HY-113516
20-HETE Ethanolamide
-
HY-165005
14S(15R)-EET methyl ester
-
HY-121987A
(±)15-HEDE
-
HY-117044A
(±)12-HEPE
-
HY-N7801
(±)5-HEPE
-
HY-145546
14(15)-EpETE
-
HY-165024
(±)5(6)-Epete methyl ester
-
HY-165022
(±)14(15)-EpEDE
Biological Activity
19(S)-HETE (1 μM; 15 min) dose-dependently induces cAMP in MEG-01 cells with an EC50 value of 520 nM[1]. 19(S)-HETE (1 μM-1 M) dose-dependently activates the IP receptor with an EC50 value of 567 nM[1]. 19(S)-HETE (10 μM-1 M) displaces 3H-iloprost of IP receptor expressed COS-1 cells with a Ki value of 660 nM[1]. 19(S)-HETE (3 μM) relaxes arterial blood vessels and inhibits platelet activation[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 115461-40-0
-
분자량 320.47
-
화학식 C20H32O3
-
SMILES
C[C@H](O)CCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(O)=O
-
선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
19(S)-HETE Related Classifications
HY-142972 Related Classifications
Powered by Bioz