20-HETE Ethanolamide
20-HETE Ethanolamide is a metabolite of endocannabinoid Anandamide. 20-HETE Ethanolamide binds to the rat brain cannabinoid CB1 receptor with a Ki of 985 nM.
For research use only. We do not sell to patients.
- CAS No.: 942069-11-6
- Formula: C22H37NO3
- Molecular Weight:363.53
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
The kidney microsomes metabolized anandamide to a single mono-oxygenated product, which was identified as 20-HETE-ethanolamide (EA)[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 942069-11-6
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Molecular Weight 363.53
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Formula C22H37NO3
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SMILES
O=C(NCCO)CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCCO
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Sridar C, et al. Anandamide oxidation by wild-type and polymorphically expressed CYP2B6 and CYP2D6. Drug Metab Dispos. 2011;39(5):782-788. [Content Brief]
[2]. Snider NT, et al. Anandamide metabolism by human liver and kidney microsomal cytochrome p450 enzymes to form hydroxyeicosatetraenoic and epoxyeicosatrienoic acid ethanolamides. J Pharmacol Exp Ther. 2007;321(2):590-597. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
20-HETE Ethanolamide Related Classifications
HY-113516 Related Classifications
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