942069-11-6
942069-11-6
Chemical Structure
20-HETE Ethanolamide
- CAS No.: 942069-11-6
- Formula:C22H37NO3
- Molecular Weight:363.53
IUPAC Name: (5Z,8Z,11Z,14Z)-20-hydroxy-N-(2-hydroxyethyl)icosa-5,8,11,14-tetraenamide
InChIKey: QRMZDMUHHZLRMH-DTLRTWKJSA-N
SMILES: O=C(NCCO)CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCCO
Biological Activity: 20-HETE Ethanolamide is a metabolite of endocannabinoid Anandamide. 20-HETE Ethanolamide binds to the rat brain cannabinoid CB1 receptor with a Ki of 985 nM[1][2].
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20-HETE Ethanolamide | 20-HETE Ethanolamide is a metabolite of endocannabinoid Anandamide. 20-HETE Ethanolamide binds to the rat brain cannabinoid CB1 receptor with a Ki of 985 nM. | |||||||||||||||||||||
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References
- [1]. Sridar C, et al. Anandamide oxidation by wild-type and polymorphically expressed CYP2B6 and CYP2D6. Drug Metab Dispos. 2011;39(5):782-788. [Content Brief]
- [2]. Snider NT, et al. Anandamide metabolism by human liver and kidney microsomal cytochrome p450 enzymes to form hydroxyeicosatetraenoic and epoxyeicosatrienoic acid ethanolamides. J Pharmacol Exp Ther. 2007;321(2):590-597. [Content Brief]
Keywords
