Andrastin A
Andrastin A meroterpenoid compound, is a farnesyltransferase inhibitor. Andrastin A inhibits the efflux of anticancer compounds from multidrug-resistant cancer cells. Andrastin A can be isolated from Penicillium species.
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- CAS No.: 174232-42-9
- 화학식: C28H38O7
- 분자량:486.60
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 174232-42-9
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분자량 486.60
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화학식 C28H38O7
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SMILES
CC1=C[C@@]2([C@](C)(CC[C@@]3(C(C)([C@H](CC[C@]32C=O)OC(C)=O)C)[H])[C@@](C(OC)=O)([C@@]1(C4=O)C)C(C4C)=O)[H]
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Structure Classification
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Initial Source
Penicillium sp. FO-3929
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Nielsen KF, et al. Andrastins A-D, Penicillium roqueforti Metabolites consistently produced in blue-mold-ripened cheese. J Agric Food Chem. 2005 Apr 20;53(8):2908-13. [Content Brief]
[2]. Rojas-Aedo JF, et al. The Biosynthetic Gene Cluster for Andrastin A in Penicillium roqueforti. Front Microbiol. 2017 May 5;8:813. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)