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SHP2-IN-35

SHP2-IN-35 (Compound 3f) is the inhibitor for SHP2. SHP2-IN-35 exhibits antiproliferative activity in cancer cells RKO, SW480 and CT26 with IC50 of 5.72 μM, 3.71 μM and 1.42 μM, respectively. SHP2-IN-35 inhibits the PI3K-Akt signaling pathway, regulates the cell cycle associated gene expressions, and induces mitochondrial-related autophagy. SHP2-IN-35 inhibits the expression of certain cytokines and chemokines in the tumor microenvironment (TME), thereby regulating the tumor progression.

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  • 화학식: C34H32FeO6
  • 분자량:592.46
  • 보관:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • SHP2-IN-35 Chemical Structure
    SHP2-IN-35 Chemical Structure
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주변의 대리점 찾기 Your local distributor: Hycultec GmbHHycultec
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  • SHP2-IN-35 Chemical Structure
    SHP2-IN-35 Chemical Structure
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  • SHP2-IN-35