2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. L-Citrulline DL-malate

L-Citrulline (DL-malate) is an organic compound commonly used as a nutritional supplement. It boosts the body's production of nitrogen oxides, improves circulation and athletic performance, and reduces muscle fatigue. In addition, L-Citrulline DL-malate also plays an important role in some industrial fields, for example, it is used in the field of agriculture to enhance plant immunity.

For research use only. We do not sell to patients.

CAS No. : 70796-17-7

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Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
ready for reconstitution
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Solution
10 mM * 1 mL in Water In-stock
Solid
1 g In-stock
5 g In-stock
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Customer Review

Based on 6 publication(s) in Google Scholar

Other Forms of L-Citrulline DL-malate:

L-Citrulline DL-malate Related Antibodies

Top Publications Citing Use of Products

    L-Citrulline DL-malate purchased from MedChemExpress. Usage Cited in: NPJ Biofilms Microbiomes. 2025 Oct 30;11(1):202.  [Abstract]

    L-Citrulline (Citr; 5 mM; 48 h). The representative images of ROS immunofluorescence of TM4 cell line in each group. Citr, treated with Citr; Sucrose, treated with Sucrose; Sucrose +H2O2, treated with Sucrose and Citr.

    L-Citrulline DL-malate purchased from MedChemExpress. Usage Cited in: NPJ Biofilms Microbiomes. 2025 Oct 30;11(1):202.  [Abstract]

    L-Citrulline (Citr; 5 mM; 48 h). Western blot of γH2AX and GAPDH in each indicated group.

    L-Citrulline DL-malate purchased from MedChemExpress. Usage Cited in: NPJ Biofilms Microbiomes. 2025 Oct 30;11(1):202.  [Abstract]

    L-Citrulline (Citr; 5 mM; 48 h). RT-qPCR analyzing the expression of Pcna and Gtf2h5 in each indicated group (n = 3).

    L-Citrulline DL-malate purchased from MedChemExpress. Usage Cited in: Exp Ther Med. 2022 Aug 22;24(4):632.

    L-Citrulline (Cit; 1 g/kg/day; ip). Representative histological changes of lung tissue. Scale bar, 100 µm.

    L-Citrulline DL-malate purchased from MedChemExpress. Usage Cited in: Exp Ther Med. 2022 Aug 22;24(4):632.

    L-Citrulline (Cit; 1 g/kg/day; ip). Representative macrophage infiltration shown as F4/80-positive cells. Sections were stained with primary antibodies against F4/80 (red), while the nucleus was stained with DAPI (blue). Scale bar, 100 µm. LPS, lipopolysaccharide; Con, control; Cit, citrulline.

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    Human Endogenous Metabolite Microbial Metabolite

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    Description

    L-Citrulline (DL-malate) is an organic compound commonly used as a nutritional supplement. It boosts the body's production of nitrogen oxides, improves circulation and athletic performance, and reduces muscle fatigue. In addition, L-Citrulline DL-malate also plays an important role in some industrial fields, for example, it is used in the field of agriculture to enhance plant immunity.

    IC50 & Target

    Human Endogenous Metabolite

     

    In Vitro

    L-Citrulline DL-malate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    L-Citrulline DL-malate Related Antibodies
    Molecular Weight

    309.27

    Formula

    C10H19N3O8
    CAS No.
    Appearance

    Solid

    Color

    White to off-white

    SMILES

    N[C@H](C(O)=O)CCCNC(N)=O.O=C(C(CC(O)=O)O)O
    Structure Classification
    Initial Source
    Shipping

    Room temperature in continental US; may vary elsewhere.
    Storage

    4°C, sealed storage, away from moisture

    *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

    Solvent & Solubility
    In Vitro: 

    H2O : 175 mg/mL (565.85 mM; Need ultrasonic)

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 3.2334 mL 16.1671 mL 32.3342 mL
    5 mM 0.6467 mL 3.2334 mL 6.4668 mL
    View the Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

    • Molarity Calculator

    • Dilution Calculator

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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    This equation is commonly abbreviated as: C1V1 = C2V2

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    In Vivo Dissolution Calculator
    Please enter the basic information of animal experiments:

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    Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
    Calculation results:
    Working solution concentration: mg/mL
    This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
    The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
    Purity & Documentation

    Purity: 99.9%

    SDS (393 KB)

    COA (251 KB) HNMR (185 KB) RP-HPLC (203 KB)

    Handling Instructions (2659 KB)

    Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

    Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
    H2O 1 mM 3.2334 mL 16.1671 mL 32.3342 mL 80.8355 mL
    5 mM 0.6467 mL 3.2334 mL 6.4668 mL 16.1671 mL
    10 mM 0.3233 mL 1.6167 mL 3.2334 mL 8.0836 mL
    15 mM 0.2156 mL 1.0778 mL 2.1556 mL 5.3890 mL
    20 mM 0.1617 mL 0.8084 mL 1.6167 mL 4.0418 mL
    25 mM 0.1293 mL 0.6467 mL 1.2934 mL 3.2334 mL
    30 mM 0.1078 mL 0.5389 mL 1.0778 mL 2.6945 mL
    40 mM 0.0808 mL 0.4042 mL 0.8084 mL 2.0209 mL
    50 mM 0.0647 mL 0.3233 mL 0.6467 mL 1.6167 mL
    60 mM 0.0539 mL 0.2695 mL 0.5389 mL 1.3473 mL
    80 mM 0.0404 mL 0.2021 mL 0.4042 mL 1.0104 mL
    100 mM 0.0323 mL 0.1617 mL 0.3233 mL 0.8084 mL

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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    L-Citrulline DL-malate Related Classifications

    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    L-Citrulline DL-malate70796-17-7Endogenous Metabolitebiochemical assayreagentInhibitorinhibitorinhibit

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