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  4. L-γ-Glutamyl-p-nitroanilide

L-γ-Glutamyl-p-nitroanilide Monohydrate is a glutamic acid derivative.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

CAS No. : 7300-59-6

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 In-stock
Solution
10 mM * 1 mL in DMSO In-stock
Solid
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Customer Review

Based on 7 publication(s) in Google Scholar

Other Forms of L-γ-Glutamyl-p-nitroanilide:

L-γ-Glutamyl-p-nitroanilide Related Antibodies

Top Publications Citing Use of Products

    L-γ-Glutamyl-p-nitroanilide purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Aug 10:e07057.  [Abstract]

    Changes in blue light intensity over time in cells pretreated with different inhibitors using GPNA hydrochloride (250/500 µM).

    L-γ-Glutamyl-p-nitroanilide purchased from MedChemExpress. Usage Cited in: Clin Respir J. 2024 Aug;18(8):e13825.  [Abstract]

    GPNA hydrochloride (2 mM).Cell viability detection.

    L-γ-Glutamyl-p-nitroanilide purchased from MedChemExpress. Usage Cited in: Clin Respir J. 2024 Aug;18(8):e13825.  [Abstract]

    GPNA hydrochloride (2 mM).MMP‐2 and MMP‐9 expression detection.

    L-γ-Glutamyl-p-nitroanilide purchased from MedChemExpress. Usage Cited in: Front Pharmacol. 2022 Feb 23;13:816133.  [Abstract]

    Representative time progression of Isc peaks stimulated by Gln (5 mM) with or without GPNA hydrochloride (200 μM) on the ileal mucosa.

    L-γ-Glutamyl-p-nitroanilide purchased from MedChemExpress. Usage Cited in: Antioxidants (Basel). 2021 Aug 25;10(9):1349.  [Abstract]

    The expression level of NRF2 protein was detected after treatment with BPTES (10 µM), CB-839 (5 ​​µM), R162 (20 µM) and GPNA hydrochloride (100 µM) for 24 hours.

    • Biological Activity

    • Purity & Documentation

    • References

    • Customer Review

    Description

    L-γ-Glutamyl-p-nitroanilide Monohydrate is a glutamic acid derivative[1].

    Cellular Effect
    Cell Line Type Value Description References
    C6 IC50
    70.2 μM
    Compound: 1; GPNA
    Inhibition of ASCT2-mediated glutamine transport in rat C6 cells using [3H]-glutamine after 15 mins by scintillation counting
    Inhibition of ASCT2-mediated glutamine transport in rat C6 cells using [3H]-glutamine after 15 mins by scintillation counting
    		[PMID: 26750251]
    HEK293 IC50
    1.2 mM
    Compound: 1; GPNA
    Inhibition of ASCT2-mediated glutamine transport in human HEK293 cells using [3H]-glutamine after 15 mins by scintillation counting
    Inhibition of ASCT2-mediated glutamine transport in human HEK293 cells using [3H]-glutamine after 15 mins by scintillation counting
    		[PMID: 26750251]
    HEK293 IC50
    954 μM
    Compound: 1
    Inhibition of ASCT2-mediated [3H]glutamine uptake in HEK293 cells after 15 mins by Live-cell glutamine uptake assay
    Inhibition of ASCT2-mediated [3H]glutamine uptake in HEK293 cells after 15 mins by Live-cell glutamine uptake assay
    		[PMID: 25435145]
    In Vitro

    Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    L-γ-Glutamyl-p-nitroanilide Related Antibodies
    Molecular Weight

    267.24

    Formula

    C11H13N3O5
    CAS No.
    Appearance

    Solid

    Color

    White to yellow

    Shipping

    Room temperature in continental US; may vary elsewhere.
    Storage

    4°C, sealed storage, away from moisture

    *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

    Solvent & Solubility
    In Vitro: 

    DMSO : 12.5 mg/mL (46.77 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 3.7420 mL 18.7098 mL 37.4195 mL
    5 mM 0.7484 mL 3.7420 mL 7.4839 mL
    View the Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

    • Molarity Calculator

    • Dilution Calculator

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    This equation is commonly abbreviated as: C1V1 = C2V2

    Concentration (start)

    C1

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    Volume (start)

    V1

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    C2

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    In Vivo Dissolution Calculator
    Please enter the basic information of animal experiments:

    Dosage

    mg/kg

    Animal weight
    (per animal)

    g

    Dosing volume
    (per animal)

    μL

    Number of animals

    Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
    Calculation results:
    Working solution concentration: mg/mL
    Purity & Documentation

    Purity: 99.88%

    SDS (393 KB)

    COA (246 KB) HNMR (257 KB) RP-HPLC (256 KB) MS (68 KB)

    Handling Instructions (2659 KB)
    References

    Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

    Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
    DMSO 1 mM 3.7420 mL 18.7098 mL 37.4195 mL 93.5489 mL
    5 mM 0.7484 mL 3.7420 mL 7.4839 mL 18.7098 mL
    10 mM 0.3742 mL 1.8710 mL 3.7420 mL 9.3549 mL
    15 mM 0.2495 mL 1.2473 mL 2.4946 mL 6.2366 mL
    20 mM 0.1871 mL 0.9355 mL 1.8710 mL 4.6774 mL
    25 mM 0.1497 mL 0.7484 mL 1.4968 mL 3.7420 mL
    30 mM 0.1247 mL 0.6237 mL 1.2473 mL 3.1183 mL
    40 mM 0.0935 mL 0.4677 mL 0.9355 mL 2.3387 mL
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    L-γ-Glutamyl-p-nitroanilide Related Classifications

    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    L-γ-Glutamyl-p-nitroanilide7300-59-6Amino Acid DerivativesInhibitorinhibitorinhibit

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