L-γ-Glutamyl-p-nitroanilide hydrate
Based on 7 publication(s) in Google Scholar
L-γ-Glutamyl-p-nitroanilide (hydrate) is aglutamic acid derivatives.
For research use only. We do not sell to patients.
- Purity: 99.26%
- CAS No.: 122864-94-2
- Formula: C11H15N3O6
- Molecular Weight:285.25
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications Citing Use of MedChemExpress (MCE) L-γ-Glutamyl-p-nitroanilide hydrate
More- Adv Sci (Weinh). 2025 Aug 10:e07057. [Abstract]
- Antioxidants (Basel). 2021 Aug 25;10(9):1349. [Abstract]
- Biochem Pharmacol. 2023 Oct:216:115767. [Abstract]
- Int Immunopharmacol. 2023 Jun:119:110216. [Abstract]
- Front Pharmacol. 2022 Feb 23;13:816133. [Abstract]
- Clin Respir J. 2024 Aug;18(8):e13825. [Abstract]
- Tohoku J Exp Med. 2024 Nov 14;264(1):31-39. [Abstract]
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Others
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Cell Proliferation/Viability Assay
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WB
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Others
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WB
Biological Activity
Chemical Information
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CAS No. 122864-94-2
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Appearance Solid
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Molecular Weight 285.25
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Formula C11H15N3O6
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Color Light yellow to yellow
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (7)
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Journal Impact Factor
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Most Recent
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Adv Sci (Weinh)
Real-Time Tracking of ASCT2-Mediated Glutamine Uptake in Living Tumors With a Bioorthogonal Bioluminescent Probe. [Abstract]2025 Aug 10:e07057. PMID: 40783801
L-γ-Glutamyl-p-nitroanilide hydrate purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Aug 10:e07057. [Abstract]
Changes in blue light intensity over time in cells pretreated with different inhibitors using GPNA hydrochloride (250/500 µM).
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Antioxidants (Basel)
Glutamine Modulates Expression and Function of Glucose 6-Phosphate Dehydrogenase via NRF2 in Colon Cancer Cells. [Abstract]2021 Aug 25;10(9):1349. PMID: 34572981
L-γ-Glutamyl-p-nitroanilide hydrate purchased from MedChemExpress. Usage Cited in: Antioxidants (Basel). 2021 Aug 25;10(9):1349. [Abstract]
The expression level of NRF2 protein was detected after treatment with BPTES (10 µM), CB-839 (5 µM), R162 (20 µM) and GPNA hydrochloride (100 µM) for 24 hours.
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Biochem Pharmacol
ASCT2-mediated glutamine uptake promotes Th1 differentiation via ROS-EGR1-PAC1 pathway in oral lichen planus. [Abstract]2023 Oct:216:115767. PMID: 37634599 -
Int Immunopharmacol
ASCT2-mediated glutamine uptake of epithelial cells facilitates CCL5-induced T cell infiltration via ROS-STAT3 pathway in oral lichen planus. [Abstract]2023 Jun:119:110216. PMID: 37116342 -
Front Pharmacol
Ca2+-Permeable Channels/Ca2+ Signaling in the Regulation of Ileal Na+/Gln Co-Transport in Mice. [Abstract]2022 Feb 23;13:816133. PMID: 35281933
L-γ-Glutamyl-p-nitroanilide hydrate purchased from MedChemExpress. Usage Cited in: Front Pharmacol. 2022 Feb 23;13:816133. [Abstract]
Representative time progression of Isc peaks stimulated by Gln (5 mM) with or without GPNA hydrochloride (200 μM) on the ileal mucosa.
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Clin Respir J
TFAP2A Activates S100A2 to Mediate Glutamine Metabolism and Promote Lung Adenocarcinoma Metastasis. [Abstract]2024 Aug;18(8):e13825. PMID: 39187936
L-γ-Glutamyl-p-nitroanilide hydrate purchased from MedChemExpress. Usage Cited in: Clin Respir J. 2024 Aug;18(8):e13825. [Abstract]
GPNA hydrochloride (2 mM).Cell viability detection.
L-γ-Glutamyl-p-nitroanilide hydrate purchased from MedChemExpress. Usage Cited in: Clin Respir J. 2024 Aug;18(8):e13825. [Abstract]
GPNA hydrochloride (2 mM).MMP‐2 and MMP‐9 expression detection.
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Tohoku J Exp Med
HJURP Derived from Cancer-Associated Fibroblasts Promotes Glutamine Metabolism to Induce Resistance to Doxorubicin in Ovarian Cancer. [Abstract]2024 Nov 14;264(1):31-39. PMID: 38866531
Solvent & Solubility
DMSO : 4 mg/mL (14.02 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (245 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.5057 mL | 17.5285 mL | 35.0570 mL | 87.6424 mL |
| 5 mM | 0.7011 mL | 3.5057 mL | 7.0114 mL | 17.5285 mL | |
| 10 mM | 0.3506 mL | 1.7528 mL | 3.5057 mL | 8.7642 mL |