Lenalidomide 4'-PEG2-amine dihydrochloride
Based on 1 Customer Validation
Lenalidomide 4'-PEG2-amine dihydrochloride is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide 4'-PEG2-amine dihydrochloride can be connected to the ligand for protein by a linker to form PROTAC.
For research use only. We do not sell to patients.
- Purity: 98.78%
- CAS No.: 2624336-88-3
- Formula: C19H28Cl2N4O5
- Molecular Weight:463.36
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
All E3 Ligase Ligand-Linker Conjugates Isoforms
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Biological Activity
Chemical Information
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CAS No. 2624336-88-3
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Appearance Solid
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Molecular Weight 463.36
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Formula C19H28Cl2N4O5
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Color Light yellow to yellow
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SMILES
O=C1NC(C(CC1)N2C(C3=C(C2)C(NCCOCCOCCN)=CC=C3)=O)=O.Cl.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 70 mg/mL (151.07 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.1581 mL | 10.7907 mL | 21.5815 mL | 53.9537 mL |
| 5 mM | 0.4316 mL | 2.1581 mL | 4.3163 mL | 10.7907 mL | |
| 10 mM | 0.2158 mL | 1.0791 mL | 2.1581 mL | 5.3954 mL | |
| 15 mM | 0.1439 mL | 0.7194 mL | 1.4388 mL | 3.5969 mL | |
| 20 mM | 0.1079 mL | 0.5395 mL | 1.0791 mL | 2.6977 mL | |
| 25 mM | 0.0863 mL | 0.4316 mL | 0.8633 mL | 2.1581 mL | |
| 30 mM | 0.0719 mL | 0.3597 mL | 0.7194 mL | 1.7985 mL | |
| 40 mM | 0.0540 mL | 0.2698 mL | 0.5395 mL | 1.3488 mL | |
| 50 mM | 0.0432 mL | 0.2158 mL | 0.4316 mL | 1.0791 mL | |
| 60 mM | 0.0360 mL | 0.1798 mL | 0.3597 mL | 0.8992 mL | |
| 80 mM | 0.0270 mL | 0.1349 mL | 0.2698 mL | 0.6744 mL | |
| 100 mM | 0.0216 mL | 0.1079 mL | 0.2158 mL | 0.5395 mL |