Lipid Azide

DSG-PEG2000-N3 is a conjugate composed of DSG, PEG chains, and terminal azido groups (-N3). DSG-PEG2000-Azide is a click chemistry reagent used for the targeted modification of liposomes/nanoparticles.

DSG-PEG1000-N3 is a conjugate composed of DSG, PEG chains, and terminal azido groups (-N3). DSG-PEG1000-Azide is a click chemistry reagent used for the targeted modification of liposomes/nanoparticles.

DPPE-PEG5-azide (DPPE-PEG5-N3) is a PEG-modified lipid containing an azide group. DPPE-PEG5-azide can undergo a copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkynyl group. It can also undergo ring strain-driven alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

DPPE-PEG1-azide (DPPE-PEG1-N3) is a PEG-modified lipid containing an azide group. DPPE-PEG1-azide can undergo a copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkynyl group. It can also undergo ring strain-driven alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Cholesterol-PEG8-azide is a PEG derivative composed of Cholesterol, 8 PEG units and an azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-driven alkyne-azide cycloaddition reaction (SPAAC) with molecules containing DBCO or BCN groups.

Trifunctional fatty acid is a clickable fatty acid.

C6(6-Azido) LacCer is a clickable sphingolipid.

C6(6-Azido) gluCer is a lipid containing an omega-terminal azide. C6(6-Azido) gluCer is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

C6(6-Azido) GalCer is a clickable sphingolipid.

Azido sphingosine (d14:1) is a clickable sphingolipid that can be used in click chemistry reactions.

16:0 Azidoethyl SM (d18:1/16:0) is a clickable phospholipid.

DSPE-PEG1-azide (DSPE-PEG1-N3) is an azide containing lipid that can be used to form micelles as nanoparticles for drug delivery. DSPE-PEG1-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

DSPE-PEG46-N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. DSPE-PEG46-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

DSPE-PEG8-azide (DSPE-PEG8-N3) is an azide containing lipid that can be used to form micelles as nanoparticles for drug delivery. DSPE-PEG8-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

DSPE-PEG1000-azide is a phospholipid with covalently attached polydisperse PEG. This polymer is commonly used for the preparation of long circulating liposomes. The azide moiety is reactive with alkyne to form a stable triazole bond.

N3C14SOBRAC is a SOBRAC with an azide group at the end can be used in click chemical reactions. SOBRAC is an inhibitor of acidic ceramidase.

Azido-erythro-sphingosines is an intermidate for synthesis of lipid molecules with two hydroxyl groups and a terminal azide group. Azide (N3) group can react with alkyne, BCN, DBCO via Click Chemistry. The hydroxyl groups enable further derivatization or replacement with other reactive functional groups. Azido-erythro-sphingosine is a derivative of Sphingosine, which is a selective inhibitor of protein kinase C activity and phorbol dibutyrate binding in vitro in human platelets.

Azido sphingosine (d18:1) is a clickable sphingolipid.

DSPE-PEG600-azide is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG600-azide can be used in drug delivery research.