MC-Gly-Gly-D-Phe

Cat. No.: HY-44235A: FAQs
Data Sheet Handling Instructions

Molarity Calculator

MC-Gly-Gly-D-Phe is a cleavable linker used for sythesis of antibody-drug conjugates (ADC).

For research use only. We do not sell to patients.

MC-Gly-Gly-D-Phe Chemical Structure

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Other Forms of MC-Gly-Gly-D-Phe:

MC-Gly-Gly-Phe In-stock

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Biological Activity
Purity & Documentation
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Description

MC-Gly-Gly-D-Phe is a cleavable linker used for sythesis of antibody-drug conjugates (ADC).

IC₅₀ & Target

Cleavable Linker

Molecular Weight

472.49

Formula

C₂₃H₂₈N₄O₇

SMILES

O=C(O)[C@@H](CC1=CC=CC=C1)NC(CNC(CNC(CCCCCN2C(C=CC2=O)=O)=O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility

In Vitro:

DMSO : 10 mg/mL (21.16 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.1164 mL	10.5822 mL	21.1645 mL
5 mM	0.4233 mL	2.1164 mL	4.2329 mL
10 mM	0.2116 mL	1.0582 mL	2.1164 mL

View the Complete Stock Solution Preparation Table

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.1164 mL	10.5822 mL	21.1645 mL	52.9112 mL
	5 mM	0.4233 mL	2.1164 mL	4.2329 mL	10.5822 mL
	10 mM	0.2116 mL	1.0582 mL	2.1164 mL	5.2911 mL
	15 mM	0.1411 mL	0.7055 mL	1.4110 mL	3.5274 mL
	20 mM	0.1058 mL	0.5291 mL	1.0582 mL	2.6456 mL

MC-Gly-Gly-D-Phe Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MC-Gly-Gly-D-PheADC LinkerAntibody-drug conjugates linkerInhibitorinhibitorinhibit

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