Methotrexate-alpha-alanine
Methotrexate-alpha-alanine is a prodrug for activation by enzyme-monoclonal antibody conjugates of Methotrexate (HY-14519). Methotrexate-alpha-alanine shows cytotoxicity.
For research use only. We do not sell to patients.
- CAS No.: 116819-28-4
- Formula: C23H27N9O6
- Molecular Weight:525.52
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 116819-28-4
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Molecular Weight 525.52
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Formula C23H27N9O6
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SMILES
NC1=NC(N)=NC2=C1N=C(CN(C3=CC=C(C=C3)C(N[C@@H](CCC(O)=O)C(N[C@@H](C)C(O)=O)=O)=O)C)C=N2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Haenseler E, et al. Activation of methotrexate-alpha-alanine by carboxypeptidase A-monoclonal antibody conjugate. Biochemistry. 1992 Jan 28;31(3):891-7. [Content Brief]
[2]. Huennekens FM. Development of methotrexate alpha-peptides as prodrugs for activation by enzyme-monoclonal antibody conjugates. Adv Enzyme Regul. 1997;37:77-92. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Methotrexate-alpha-alanine Related Classifications
HY-165164 Related Classifications
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