Microtubulin-IN-1
Microtubulin-IN-1 (Compound 8g) is the inhibitor for microtubulin that targets colchicine-binding site, disrupts the microtubulin integrity, and induces the upregulation of p53. Microtubulin-IN-1 exhibits antiproliferative activity in a variety of cancer cell lines (IC50 for NCI-H460, BxPC-3 and HT-29 is 2.4, 1.6 and 2.07 nM, respectively), arrests the cell cycle at G2/M phase, and induces apoptosis in NCI-H460.
For research use only. We do not sell to patients.
- CAS No.: 3025180-14-4
- Formula: C25H21FN4O3
- Molecular Weight:444.46
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Chemical Information
-
CAS No. 3025180-14-4
-
Molecular Weight 444.46
-
Formula C25H21FN4O3
-
SMILES
FC1=CC=C(C(C2=CC=CC(/C=C3NC(/C(NC\3=O)=C/C4=NC=CN4C(C)C)=O)=C2)=O)C=C1
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Microtubulin-IN-1 Related Classifications
HY-173074 Related Classifications
Powered by Bioz