1. Metabolic Enzyme/Protease
  2. Mitochondrial Metabolism
  3. Mitochondrial respiration-IN-1 hydrobromide

Mitochondrial respiration-IN-1 hydrobromide 

Cat. No.: HY-131453A Purity: 99.51%
Handling Instructions

Mitochondrial respiration-IN-1 hydrobromide (compound 49) is a potent mitochondrial inhibitor (IC50=8.8 mg/mL) extracted from patent US20110301180A1, compound 49. Mitochondrial respiration-IN-1 hydrobromide significantly reduces mitochondrial respiration in platelets.

For research use only. We do not sell to patients.

Mitochondrial respiration-IN-1 hydrobromide Chemical Structure

Mitochondrial respiration-IN-1 hydrobromide Chemical Structure

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 468 In-stock
Estimated Time of Arrival: December 31
5 mg USD 350 In-stock
Estimated Time of Arrival: December 31
10 mg USD 550 In-stock
Estimated Time of Arrival: December 31
25 mg USD 950 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1450 In-stock
Estimated Time of Arrival: December 31
100 mg USD 2250 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
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Description

Mitochondrial respiration-IN-1 hydrobromide (compound 49) is a potent mitochondrial inhibitor (IC50=8.8 mg/mL) extracted from patent US20110301180A1, compound 49. Mitochondrial respiration-IN-1 hydrobromide significantly reduces mitochondrial respiration in platelets[1].

Molecular Weight

607.34

Formula

C₂₆H₂₆Br₂NO₂PS

SMILES

O=C(OCCC1=C(C)N=CS1)C[P+](C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4.[H]Br.[Br-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 66.67 mg/mL (109.77 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6465 mL 8.2326 mL 16.4652 mL
5 mM 0.3293 mL 1.6465 mL 3.2930 mL
10 mM 0.1647 mL 0.8233 mL 1.6465 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 5 mg/mL (8.23 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 5 mg/mL (8.23 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 5 mg/mL (8.23 mM); Clear solution

*All of the co-solvents are provided by MCE.
References

Purity: 99.51%

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Keywords:

Mitochondrial respiration-IN-1Mitochondrial MetabolismmitochondrialrespirationplateletspatentInhibitorinhibitorinhibit

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Product Name:
Mitochondrial respiration-IN-1 hydrobromide
Cat. No.:
HY-131453A
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