2. Neuronal Signaling
  3. Monoamine Oxidase
  4. Monoamine Oxidase B inhibitor 5

Monoamine Oxidase B inhibitor 5 (Compound 16d) is a selective and reversible inhibitor for monoamine oxidase B (hMAO-B) with an IC50 of 67.3 nM and a Ki of 82.5 nM. Monoamine Oxidase B inhibitor 5 exhibits good pharmacokinetic characters and weak toxicity in rats model. Monoamine Oxidase B inhibitor 5 alleviates MPTP-induced (HY-15608) motor impairment in Parkinson’s mouse model. Monoamine Oxidase B inhibitor 5 is blood-brain barrier (BBB) penetrate.

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Monoamine Oxidase B inhibitor 5

Monoamine Oxidase B inhibitor 5 Estructura química

No. CAS : 2969160-15-2

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Monoamine Oxidase B inhibitor 5 Related Antibodies

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MAO-A MAO-B

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Descripciòn

Monoamine Oxidase B inhibitor 5 (Compound 16d) is a selective and reversible inhibitor for monoamine oxidase B (hMAO-B) with an IC50 of 67.3 nM and a Ki of 82.5 nM. Monoamine Oxidase B inhibitor 5 exhibits good pharmacokinetic characters and weak toxicity in rats model. Monoamine Oxidase B inhibitor 5 alleviates MPTP-induced (HY-15608) motor impairment in Parkinson’s mouse model. Monoamine Oxidase B inhibitor 5 is blood-brain barrier (BBB) penetrate[1].

IC50 & Target

hMAO-B

67.3 nM (IC50)

hMAO-A

26014 nM (IC50)

Peso molecular

299.30

Fòrmula

C16H14FN3O2
No. CAS
SMILES

FC1=CC=C(COC2=CC=C(NC(CC(N)=O)=N3)C3=C2)C=C1
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
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Monoamine Oxidase B inhibitor 5 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Monoamine Oxidase B inhibitor 52969160-15-2Monoamine Oxidase B inhibitor5Monoamine Oxidase B inhibitor-5Monoamine OxidaseMAOParkinson's diseasePDsafinamidePC12Inhibitorinhibitorinhibit

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Nombre del producto:
Monoamine Oxidase B inhibitor 5
Cat. No.:
HY-162573
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