Monoamine Oxidase B inhibitor 5
Monoamine Oxidase B inhibitor 5 (Compound 16d) is a selective and reversible inhibitor for monoamine oxidase B (hMAO-B) with an IC50 of 67.3 nM and a Ki of 82.5 nM. Monoamine Oxidase B inhibitor 5 exhibits good pharmacokinetic characters and weak toxicity in rats model. Monoamine Oxidase B inhibitor 5 alleviates MPTP-induced (HY-15608) motor impairment in Parkinson’s mouse model. Monoamine Oxidase B inhibitor 5 is blood-brain barrier (BBB) penetrate.
For research use only. We do not sell to patients.
- CAS No.: 2969160-15-2
- Formula: C16H14FN3O2
- Molecular Weight:299.30
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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hMAO-B 67.3 nM (IC50) |
hMAO-A 26014 nM (IC50) |
Chemical Information
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CAS No. 2969160-15-2
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Molecular Weight 299.30
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Formula C16H14FN3O2
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SMILES
FC1=CC=C(COC2=CC=C(NC(CC(N)=O)=N3)C3=C2)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)