2. Apoptosis
  3. c-Myc
  4. Mycro2

Mycro2 is an inhibitor of c-Myc/Max dimer and DNA binding, with an IC50 value of 23 μM for the inhibition of Myc/Max DNA binding activity. Mycro2 can inhibit c-myc-dependent cell proliferation, gene transcription and oncogenic transformation.

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Mycro2

Mycro2 화학구조

CAS No. : 314049-21-3

사이즈 가격 재고 수량
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 해외재고보유
Solution
10 mM * 1 mL in DMSO 해외재고보유
Solid
1 mg 해외재고보유
5 mg 해외재고보유
10 mg 해외재고보유
25 mg 해외재고보유
50 mg 해외재고보유
100 mg   견적 받기  
200 mg   견적 받기  

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Mycro2 Related Antibodies

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제품 설명

Mycro2 is an inhibitor of c-Myc/Max dimer and DNA binding, with an IC50 value of 23 μM for the inhibition of Myc/Max DNA binding activity. Mycro2 can inhibit c-myc-dependent cell proliferation, gene transcription and oncogenic transformation[1].

In Vitro

Mycro2 (10 or 20 μM, 7 days) can inhibit the proliferation of C-Myc-dependent cell lines U-2OS, MCF-7, Raji and NIH/3T3, but does not inhibit the proliferation of C-Myc-independent cancer cell line PC-12. Mycro2 significantly inhibits c-myc-induced gene transcription at 10 μM and selectively reduces unanchored growth of c-myc-transformed Rat1a cells at 20 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Mycro2 Related Antibodies
분자량

408.42

화학식

C17H11F3N4OS2
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C(C1=NN2C(C(F)(F)F)=CC(C3=CC=CS3)=NC2=C1)NCC4=CC=CS4
선적

Room temperature in continental US; may vary elsewhere.
보관
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
용액&용해도
In Vitro: 

DMSO : 125 mg/mL (306.06 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4485 mL 12.2423 mL 24.4846 mL
5 mM 0.4897 mL 2.4485 mL 4.8969 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • 몰농도 계산기

  • 농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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mg/kg

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(per animal)

g

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
순도&문서

Purity: 99.81%

SDS (251 KB)

COA (251 KB) LCMS (94 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4485 mL 12.2423 mL 24.4846 mL 61.2115 mL
5 mM 0.4897 mL 2.4485 mL 4.8969 mL 12.2423 mL
10 mM 0.2448 mL 1.2242 mL 2.4485 mL 6.1211 mL
15 mM 0.1632 mL 0.8162 mL 1.6323 mL 4.0808 mL
20 mM 0.1224 mL 0.6121 mL 1.2242 mL 3.0606 mL
25 mM 0.0979 mL 0.4897 mL 0.9794 mL 2.4485 mL
30 mM 0.0816 mL 0.4081 mL 0.8162 mL 2.0404 mL
40 mM 0.0612 mL 0.3061 mL 0.6121 mL 1.5303 mL
50 mM 0.0490 mL 0.2448 mL 0.4897 mL 1.2242 mL
60 mM 0.0408 mL 0.2040 mL 0.4081 mL 1.0202 mL
80 mM 0.0306 mL 0.1530 mL 0.3061 mL 0.7651 mL
100 mM 0.0245 mL 0.1224 mL 0.2448 mL 0.6121 mL
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Mycro2 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Mycro2314049-21-3Mycro 2Mycro-2c-MycMycc-Myc/Maxcell proliferationgene transcriptiononcogenic transformationInhibitorinhibitorinhibit

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상품명:
Mycro2
Cat. No.:
HY-126979
수량:
MCE Japan Authorized Agent:

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SAFETY DATA SHEET (SDS)

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