1. Cell Cycle/DNA Damage Cytoskeleton
  2. Mitosis Microtubule/Tubulin
  3. N-Boc-dolaproine dicyclohexylamine

N-Boc-dolaproine dicyclohexylamine  (Synonyms: (2R,3R)-BOC-dolaproine dicyclohexylamine)

Cat. No.: HY-33046A Pureté: 99.93%
Instruction de manipulation Technical Support

N-Boc-dolaproine dicyclohexylamine is an amino acid residue of the pentapeptide Dolastatin 10 (HY-15580). Dolastatin 10 inhibits tubulin polymerization and mitosis and has anticancer activity. And contains dicyclohexylamine.

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N-Boc-dolaproine dicyclohexylamine

N-Boc-dolaproine dicyclohexylamine Chemical Structure

CAS No. : 1369427-40-6

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Description

N-Boc-dolaproine dicyclohexylamine is an amino acid residue of the pentapeptide Dolastatin 10 (HY-15580). Dolastatin 10 inhibits tubulin polymerization and mitosis and has anticancer activity. And contains dicyclohexylamine[1].

Masse moléculaire

468.67

Formule

C26H48N2O5

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CO[C@H]([C@@H](C)C(O)=O)[C@H]1N(C(OC(C)(C)C)=O)CCC1.C2(NC3CCCCC3)CCCCC2

Livraison

Room temperature in continental US; may vary elsewhere.

Stockage

4°C, stored under nitrogen, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)

Solvant et solubilité
In Vitro: 

Ethanol : 100 mg/mL (213.37 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1337 mL 10.6685 mL 21.3370 mL
5 mM 0.4267 mL 2.1337 mL 4.2674 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Calculateur de molarité

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Pureté et documentation

Purity: 99.93%

Références

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
Ethanol 1 mM 2.1337 mL 10.6685 mL 21.3370 mL 53.3424 mL
5 mM 0.4267 mL 2.1337 mL 4.2674 mL 10.6685 mL
10 mM 0.2134 mL 1.0668 mL 2.1337 mL 5.3342 mL
15 mM 0.1422 mL 0.7112 mL 1.4225 mL 3.5562 mL
20 mM 0.1067 mL 0.5334 mL 1.0668 mL 2.6671 mL
25 mM 0.0853 mL 0.4267 mL 0.8535 mL 2.1337 mL
30 mM 0.0711 mL 0.3556 mL 0.7112 mL 1.7781 mL
40 mM 0.0533 mL 0.2667 mL 0.5334 mL 1.3336 mL
50 mM 0.0427 mL 0.2134 mL 0.4267 mL 1.0668 mL
60 mM 0.0356 mL 0.1778 mL 0.3556 mL 0.8890 mL
80 mM 0.0267 mL 0.1334 mL 0.2667 mL 0.6668 mL
100 mM 0.0213 mL 0.1067 mL 0.2134 mL 0.5334 mL
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Nom du produit:
N-Boc-dolaproine dicyclohexylamine
Cat. No.:
HY-33046A
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