2. Immunology/Inflammation NF-κB Metabolic Enzyme/Protease
  3. Reactive Oxygen Species (ROS)
  4. N-Methyl-2-HOBA hydrochloride

N-Methyl-2-HOBA hydrochloride  (Synonyms: 2-((Methylamino)methyl)phenol hydrochloride)

Cat. No.: HY-W091169 Purity: 99.62%
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N-Methyl-2-HOBA (2-((Methylamino)methyl)phenol) hydrochloride is a methylated form of the isoketal scavenger 2-HOBA (HY-34350). N-Methyl-2-HOBA hydrochloride can be used as a negative control for the activity of 2-HOBA in a mouse model of hypertension.

For research use only. We do not sell to patients.

N-Methyl-2-HOBA hydrochloride

N-Methyl-2-HOBA hydrochloride Chemical Structure

CAS No. : 63989-87-7

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
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Solution
10 mM * 1 mL in DMSO In-stock
Solid
50 mg In-stock
100 mg In-stock
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Based on 1 publication(s) in Google Scholar

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Description

N-Methyl-2-HOBA (2-((Methylamino)methyl)phenol) hydrochloride is a methylated form of the isoketal scavenger 2-HOBA (HY-34350). N-Methyl-2-HOBA hydrochloride can be used as a negative control for the activity of 2-HOBA in a mouse model of hypertension[1].

Molecular Weight

173.64

Formula

C8H12ClNO
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC1=C(CNC)C=CC=C1.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 70 mg/mL (403.13 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.7590 mL 28.7952 mL 57.5904 mL
5 mM 1.1518 mL 5.7590 mL 11.5181 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Volume
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 5.7590 mL 28.7952 mL 57.5904 mL 143.9760 mL
5 mM 1.1518 mL 5.7590 mL 11.5181 mL 28.7952 mL
10 mM 0.5759 mL 2.8795 mL 5.7590 mL 14.3976 mL
15 mM 0.3839 mL 1.9197 mL 3.8394 mL 9.5984 mL
20 mM 0.2880 mL 1.4398 mL 2.8795 mL 7.1988 mL
25 mM 0.2304 mL 1.1518 mL 2.3036 mL 5.7590 mL
30 mM 0.1920 mL 0.9598 mL 1.9197 mL 4.7992 mL
40 mM 0.1440 mL 0.7199 mL 1.4398 mL 3.5994 mL
50 mM 0.1152 mL 0.5759 mL 1.1518 mL 2.8795 mL
60 mM 0.0960 mL 0.4799 mL 0.9598 mL 2.3996 mL
80 mM 0.0720 mL 0.3599 mL 0.7199 mL 1.7997 mL
100 mM 0.0576 mL 0.2880 mL 0.5759 mL 1.4398 mL
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N-Methyl-2-HOBA hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

N-Methyl-2-HOBA63989-87-72-((Methylamino)methyl)phenolReactive Oxygen Species (ROS)methylated form2-HOBA negative controlhypertensionInhibitorinhibitorinhibit

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