Neojiangyouaconitine
Neojiangyouaconitine is a diterpenoid alkaloid cytotoxin isolated from Aconitum soongaricum var. pubescens. Neojiangyouaconitine exhibits cytotoxic activity against human breast cancer, prostate cancer and lung cancer cells, with weak inhibitory effect on HeLa cells. Neojiangyouaconitine has the ability to kill specific tumor cell lines and can be applied to the research on the mechanisms of related cancers such as breast cancer, prostate cancer and lung cancer.
For research use only. We do not sell to patients.
- CAS No.: 126266-35-1
- Formula: C33H47NO9
- Molecular Weight:601.73
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Neojiangyouaconitine (compound 9) exhibits cytotoxic activity against MCF-7, PC-3 and A549 human tumor cell lines, with IC50 values of 68.7 μM, 40.2 μM and 42.4 μM, respectively; whereas it shows no cytotoxic activity against HeLa cells (IC50>100 μM)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 126266-35-1
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Molecular Weight 601.73
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Formula C33H47NO9
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SMILES
CO[C@@H]1[C@]23[C@@]4([H])[C@]([C@@]5([C@]6([H])[C@@]3([H])C[C@@]([C@@H]6OC(C7=CC=CC=C7)=O)([C@H]([C@@H]5O)OC)O)OC)([H])[C@@H]([C@]2([H])[C@](CN4CC)(CC1)COC)OC
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)