1. Apoptosis
  2. MDM-2/p53
  3. NSC 146109 hydrochloride

NSC 146109 hydrochloride 

Cat. No.: HY-108638
Handling Instructions

NSC 146109 hydrochloride is a small-molecule p53 activator that target MDMX and could be of value in treating breast cancer. NSC 146109 hydrochloride is a pseudourea derivative, promotes breast cancer cells to undergo apoptosis through activating p53 and inducing expression of proapoptotic genes[1].

For research use only. We do not sell to patients.

NSC 146109 hydrochloride Chemical Structure

NSC 146109 hydrochloride Chemical Structure

CAS No. : 59474-01-0

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Description

NSC 146109 hydrochloride is a small-molecule p53 activator that target MDMX and could be of value in treating breast cancer. NSC 146109 hydrochloride is a pseudourea derivative, promotes breast cancer cells to undergo apoptosis through activating p53 and inducing expression of proapoptotic genes[1].

Molecular Weight

316.85

Formula

C₁₇H₁₇ClN₂S

CAS No.

59474-01-0

SMILES

[H]Cl.NC(SCC1=C2C=CC=CC2=C(C)C3=CC=CC=C13)=N

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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NSC 146109 hydrochloride
Cat. No.:
HY-108638
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