1. JAK/STAT Signaling
  2. Pim
  3. Pim-1 kinase inhibitor 3

Pim-1 kinase inhibitor 3 (Compound H5) is a potent Pim-1 kinase inhibitor with an IC50 of 35.13 nM.

For research use only. We do not sell to patients.

Pim-1 kinase inhibitor 3 Chemical Structure

Pim-1 kinase inhibitor 3 Chemical Structure

CAS No. : 2801695-39-4

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Description

Pim-1 kinase inhibitor 3 (Compound H5) is a potent Pim-1 kinase inhibitor with an IC50 of 35.13 nM[1].

IC50 & Target

PIM1

35.13 nM (IC50)

In Vitro

Pim-1 kinase inhibitor 3 (Compound H5) (0-100 μM, 48 h) inhibits MDA-MD-231 cell proliferation[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Proliferation Assay[1]

Cell Line: MDA-MD-231
Concentration: 0-100 μM
Incubation Time: 48 h
Result: Inhibited cell proliferation with an IC50 of 8.154 μM.
Molecular Weight

339.43

Formula

C20H25N3O2

CAS No.
SMILES

C12=CC3=C(C=C2)OC4=C(C=CN=C4)N3CCCCCNCCCCO1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Pim-1 kinase inhibitor 3 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Pim-1 kinase inhibitor 3
Cat. No.:
HY-150731
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