2. PROTAC
  3. Ligands for E3 Ligase
  4. Pomalidomide-C11-NH2 hydrochloride

Pomalidomide-C11-NH2 hydrochloride is the Pomalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein.Pomalidomide-C11-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTAC.

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Pomalidomide-C11-NH2 hydrochloride Chemical Structure

Pomalidomide-C11-NH2 hydrochloride Chemical Structure

CAS No. : 2722611-55-2

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Pomalidomide-C11-NH2 hydrochloride Related Antibodies

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Description

Pomalidomide-C11-NH2 hydrochloride is the Pomalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein.Pomalidomide-C11-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTAC[1].

Molecular Weight

479.01

Formula

C24H35ClN4O4
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C1N(C(C2=C1C=CC=C2NCCCCCCCCCCCN)=O)C(C(N3)=O)CCC3=O.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Purity & Documentation
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Pomalidomide-C11-NH2 hydrochloride Related Classifications

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pomalidomide-C11-NH22722611-55-2Ligands for E3 LigaseE3 ligase-recruiting MoietyMolecular gelcereblon ligandPROTACCRBN proteintarget protein ligandconjugateInhibitorinhibitorinhibit

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