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Cat. No.: HY-159165

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Pomalidomide-cyclopentane-amide-Alkyne

Pomalidomide-cyclopentane-amide-Alkyne is an E3 ligase ligand-linker conjugate that incorporates the Pomalidomide (HY-10984) and the linker cyclopentane-amide-Alkyne. Pomalidomide-cyclopentane-amide-Alkyne is used to form PROTACs, such as RGB110 (HY-159087).

For research use only. We do not sell to patients.

Formula: C₂₅H₂₆N₄O₆
Molecular Weight:478.50

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Pomalidomide-cyclopentane-amide-Alkyne Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

IC₅₀ & Target^[1]

Cereblon

All E3 Ligase Ligand-Linker Conjugates Isoforms :

Chemical Information

Molecular Weight 478.50
Formula C₂₅H₂₆N₄O₆
SMILES

C#CCNC(CC1(CCCC1)CC(NC2=C3C(N(C(C3=CC=C2)=O)C4CCC(NC4=O)=O)=O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Osipyan A, et al., The synthesis of 1,2,3-triazoles as binders of D-dopachrome tautomerase (D-DT) for the development of dual-targeting inhibitors. Eur J Med Chem. 2024 Jul 8;276:116665. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

Pomalidomide-cyclopentane-amide-Alkyne

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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Pomalidomide-cyclopentane-amide-Alkyne

All E3 Ligase Ligand-Linker Conjugates Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Pomalidomide-cyclopentane-amide-Alkyne Related Classifications

HY-159165 Related Classifications