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Cat. No.: HY-B0949S

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Protriptyline (N-methyl-d₃) hydrochloride

Protriptyline (N-methyl-d₃) (hydrochloride) is the deuterium labeled Protriptyline hydrochloride. Protriptyline hydrochloride is a tricyclic antidepressant (TCA), specifically a secondary amine, for the treatment of depression and ADHD. Unique among the TCAs, protriptyline tends to be energizing instead of sedating, used for narcolepsy to achieve a wakefulness-promoting effect.

For research use only. We do not sell to patients.

CAS No.: 1435934-21-6
Formula: C₁₉H₁₉D₃ClN
Molecular Weight:266.40

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

Protriptyline (N-methyl-d₃) hydrochloride Chemical Structure

CAS No.: 1435934-21-6

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
- Application
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

All Cholinesterase (ChE) Isoforms :

AChE
BChE

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

CAS No. 1435934-21-6
Unlabeled Cas 1225-55-4
Molecular Weight 266.40
Formula C₁₉H₁₉D₃ClN
SMILES

C(CCNC([2H])([2H])[2H])C1C=2C(C=CC=3C1=CC=CC3)=CC=CC2.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Hudgel DW. Pharmacologic treatment of obstructive sleep apnea. J Lab Clin Med. 1995;126(1):13-18. [Content Brief]

[2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Protriptyline (N-methyl-d₃) hydrochloride

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Protriptyline (N-methyl-d3) hydrochloride

All Cholinesterase (ChE) Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Protriptyline (N-methyl-d3) hydrochloride Related Classifications

HY-B0949S Related Classifications

Protriptyline (N-methyl-d₃) hydrochloride

Protriptyline (N-methyl-d₃) hydrochloride Related Classifications