PSEN1-IN-2
Based on 1 Customer Validation
PSEN1-IN-2 (Compound 13K) is a PSEN1 inhibitor. PSEN1-IN-2 inhibits PSEN1-APH1A and PSEN1-APH1B complex with IC50s of 6.9 and 2.4 nM. PSEN1-IN-2 can be used for Alzheimer's disease research.
For research use only. We do not sell to patients.
- CAS No.: 3054220-07-1
- Formula: C20H18ClFN2O3S
- Molecular Weight:420.88
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
Description
IC50 & Target
6.9 and 2.4 nM for PSEN1-APH1A and PSEN1-APH1B complex[1]
Chemical Information
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CAS No. 3054220-07-1
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Appearance Solid
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Molecular Weight 420.88
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Formula C20H18ClFN2O3S
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Color Off-white to gray
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SMILES
O[C@H]1C[C@@H]2CC[C@H]1[C@H](N2S(C3=CC=C(Cl)C=C3)(=O)=O)C4=CC=C(C#N)C=C4F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Purity & Documentation
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Data Sheet (276 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)