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Cat. No.: HY-D0143AR

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Quinine dihydrochloride (Standard)

Quinine dihydrochloride (Standard) is the analytical standard of Quinine dihydrochloride (HY-D0143A). This product is intended for research and analytical applications. Quinine dihydrochloride is an orally active alkaloid extracted from cinchona bark, possessing various biological activities including antimalarial, antidengue virus (DENV), and anticancer properties. Quinine dihydrochloride is a potassium channel inhibitor that inhibits WT mouse Slo3 (K_Ca5.1) channel currents evoked by voltage pulses to +100 mV with an IC₅₀ of 169 μM.

For research use only. We do not sell to patients.

CAS No.: 60-93-5
Formula: C₂₀H₂₆Cl₂N₂O₂
Molecular Weight:397.34

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Quinine dihydrochloride (Standard) Chemical Structure

CAS No.: 60-93-5

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 60-93-5
Molecular Weight 397.34
Formula C₂₀H₂₆Cl₂N₂O₂
SMILES

C=C[C@H](C[N@@]1CC2)[C@H]2C[C@@H]1[C@H](O)C3=CC=NC4=CC=C(OC)C=C34.Cl.Cl
Structure Classification
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Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Shilu Malakar，et al. Drug repurposing of quinine as antiviral against dengue virus infection. Virus Res. 2018 Aug 15;255:171-178. doi: 10.1016/j.virusres.2018.07.018. Epub 2018 Jul 25. [Content Brief]

[2]. Jhanwar, Deepika，et al. Chemoprevention of DMBA induced skin carcinogenesis in swiss albino mice by quinine sulfate.(2016): 2636-2640.

[3]. Ebenezer O Farombi, et al. Quercetin protects against testicular toxicity induced by chronic administration of therapeutic dose of quinine sulfate in rats. J Basic Clin Physiol Pharmacol. 2012 Feb 27;23(1):39-44. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Quinine dihydrochloride (Standard)