(R)-Fluoxetine hydrochloride

Name: (R)-Fluoxetine hydrochloride
Brand: MedChemExpress
SKU: HY-B0102C
Rating: 4.5 (1 reviews)

Cat. No.: HY-B0102C Purity: 99.82%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

(R)-Fluoxetine hydrochloride, an antidepressant, is serotonin reuptake inhibitor (SSRI). (R)-Fluoxetine hydrochloride has modest affinity at the 5-HT_2A and 5-HT_2C receptors.

For research use only. We do not sell to patients.

(R)-Fluoxetine hydrochloride Chemical Structure

CAS No. : 114247-09-5

Size	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water ready for reconstitution	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in Water	In-stock	Estimated Time of Arrival: December 31
Solid
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of (R)-Fluoxetine hydrochloride:

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Biological Activity
Purity & Documentation
References
Customer Review

Description

(R)-Fluoxetine hydrochloride, an antidepressant, is serotonin reuptake inhibitor (SSRI). (R)-Fluoxetine hydrochloride has modest affinity at the 5-HT_2A and 5-HT_2C receptors^[1]^[2].

IC₅₀ & Target

5-HT_2A Receptor

5-HT_2C Receptor

Molecular Weight

345.79

Formula

C₁₇H₁₉ClF₃NO

CAS No.

114247-09-5

Appearance

Solid

Color

White to off-white

SMILES

FC(C1=CC=C(O[C@@H](C2=CC=CC=C2)CCNC)C=C1)(F)F.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : ≥ 50 mg/mL (144.60 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.8919 mL	14.4596 mL	28.9193 mL
5 mM	0.5784 mL	2.8919 mL	5.7839 mL
10 mM	0.2892 mL	1.4460 mL	2.8919 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.82%

Select Batch:

Data Sheet (271 KB) SDS (614 KB)

COA (248 KB) HNMR (982 KB) CNMR (175 KB) RP-HPLC (147 KB) MS (212 KB)

Handling Instructions (2659 KB)

References

[1]. Henry ME, et al. A comparison of brain and serum pharmacokinetics of R-fluoxetine and racemic fluoxetine: A 19-F MRS study. Neuropsychopharmacology. 2005;30(8):1576-1583. [Content Brief]

[2]. Marwari S, et al. (R)-fluoxetine enhances cognitive flexibility and hippocampal cell proliferation in mice. J Psychopharmacol. 2018;32(4):441-457. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	2.8919 mL	14.4596 mL	28.9193 mL	72.2982 mL
	5 mM	0.5784 mL	2.8919 mL	5.7839 mL	14.4596 mL
	10 mM	0.2892 mL	1.4460 mL	2.8919 mL	7.2298 mL
	15 mM	0.1928 mL	0.9640 mL	1.9280 mL	4.8199 mL
	20 mM	0.1446 mL	0.7230 mL	1.4460 mL	3.6149 mL
	25 mM	0.1157 mL	0.5784 mL	1.1568 mL	2.8919 mL
	30 mM	0.0964 mL	0.4820 mL	0.9640 mL	2.4099 mL
	40 mM	0.0723 mL	0.3615 mL	0.7230 mL	1.8075 mL
	50 mM	0.0578 mL	0.2892 mL	0.5784 mL	1.4460 mL
	60 mM	0.0482 mL	0.2410 mL	0.4820 mL	1.2050 mL
	80 mM	0.0361 mL	0.1807 mL	0.3615 mL	0.9037 mL
	100 mM	0.0289 mL	0.1446 mL	0.2892 mL	0.7230 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.