(R)-Fluoxetine hydrochloride
Based on 1 Customer Validation
(R)-Fluoxetine hydrochloride, an antidepressant, is serotonin reuptake inhibitor (SSRI). (R)-Fluoxetine hydrochloride has modest affinity at the 5-HT2A and 5-HT2C receptors.
For research use only. We do not sell to patients.
- Purity: 99.82%
- CAS No.: 114247-09-5
- Formula: C17H19ClF3NO
- Molecular Weight:345.79
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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5-HT2A Receptor |
5-HT2C Receptor |
Chemical Information
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CAS No. 114247-09-5
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Appearance Solid
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Molecular Weight 345.79
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Formula C17H19ClF3NO
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Color White to off-white
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SMILES
FC(C1=CC=C(O[C@@H](C2=CC=CC=C2)CCNC)C=C1)(F)F.[H]Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : ≥ 50 mg/mL (144.60 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (614 KB)
- English - EN (614 KB)
- Français - FR (614 KB)
- Deutsch - DE (614 KB)
- Norwegian - NO (614 KB)
- Español - ES (614 KB)
- Swedish - SV (614 KB)
- Italian - IT (614 KB)
- Korean - KR (614 KB)
- Portuguese - PT (614 KB)
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Handling Instructions (2659 KB)
References
[1]. Henry ME, et al. A comparison of brain and serum pharmacokinetics of R-fluoxetine and racemic fluoxetine: A 19-F MRS study. Neuropsychopharmacology. 2005;30(8):1576-1583. [Content Brief]
[2]. Marwari S, et al. (R)-fluoxetine enhances cognitive flexibility and hippocampal cell proliferation in mice. J Psychopharmacol. 2018;32(4):441-457. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 2.8919 mL | 14.4596 mL | 28.9193 mL | 72.2982 mL |
| 5 mM | 0.5784 mL | 2.8919 mL | 5.7839 mL | 14.4596 mL | |
| 10 mM | 0.2892 mL | 1.4460 mL | 2.8919 mL | 7.2298 mL | |
| 15 mM | 0.1928 mL | 0.9640 mL | 1.9280 mL | 4.8199 mL | |
| 20 mM | 0.1446 mL | 0.7230 mL | 1.4460 mL | 3.6149 mL | |
| 25 mM | 0.1157 mL | 0.5784 mL | 1.1568 mL | 2.8919 mL | |
| 30 mM | 0.0964 mL | 0.4820 mL | 0.9640 mL | 2.4099 mL | |
| 40 mM | 0.0723 mL | 0.3615 mL | 0.7230 mL | 1.8075 mL | |
| 50 mM | 0.0578 mL | 0.2892 mL | 0.5784 mL | 1.4460 mL | |
| 60 mM | 0.0482 mL | 0.2410 mL | 0.4820 mL | 1.2050 mL | |
| 80 mM | 0.0361 mL | 0.1807 mL | 0.3615 mL | 0.9037 mL | |
| 100 mM | 0.0289 mL | 0.1446 mL | 0.2892 mL | 0.7230 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
(R)-Fluoxetine hydrochloride Related Classifications
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