(±)-Camphor-10-sulfonic acid
Based on 1 Customer Validation
(±)-Camphor-10-sulfonic acid is a racemate of Camphor-10-sulfonic acid. (±)-Camphor-10-sulfonic acid can be used as an organocatalyst in performing a huge array of organic transformations.
For research use only. We do not sell to patients.
- Purity : 99.83%
- CAS No.: 5872-08-2
- Formula: C10H16O4S
- Molecular Weight:232.30
-
Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Description
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| B-cell | IC50 |
<0.04 μM
Compound: CsA
|
Immunosuppressive activity in BALB/c mouse B-lymphocytes assessed as inhibition of LPS-induced cell proliferation pretreated with LPS for 24 hrs followed by compound addition and measured after 48 hrs by CCK-8 assay
Immunosuppressive activity in BALB/c mouse B-lymphocytes assessed as inhibition of LPS-induced cell proliferation pretreated with LPS for 24 hrs followed by compound addition and measured after 48 hrs by CCK-8 assay
|
[PMID: 39033406] |
| T-cell | IC50 |
<0.04 μM
Compound: CsA
|
Immunosuppressive activity in BALB/c mouse T-lymphocytes assessed as inhibition of ConA-induced cell proliferation pretreated with Concanavalin A for 24 hrs followed by compound addition and measured after 48 hrs by CCK-8 assay
Immunosuppressive activity in BALB/c mouse T-lymphocytes assessed as inhibition of ConA-induced cell proliferation pretreated with Concanavalin A for 24 hrs followed by compound addition and measured after 48 hrs by CCK-8 assay
|
[PMID: 39033406] |
In Vitro
(±)-Camphor-10-sulfonic acid is Brönsted acid catalyst, which provides protons (H+) to reduce the activation energy of the reaction. (±)-Camphor-10-sulfonic acid catalyzes many types of reactions, such as Friedel-Crafts reaction, Michael addition reaction and Mannich reaction[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 5872-08-2
-
Appearance Solid
-
Molecular Weight 232.30
-
Formula C10H16O4S
-
Color White to off-white
-
SMILES
O=C1CC2CCC1(C2(C)C)CS(=O)(O)=O
-
Synonyms
(±)-10-Camphorsulfonic acid
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (430.48 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (280 KB)
-
SDS (477 KB)
- English - EN (477 KB)
- Français - FR (477 KB)
- Deutsch - DE (477 KB)
- Norwegian - NO (477 KB)
- Español - ES (477 KB)
- Swedish - SV (477 KB)
- Italian - IT (477 KB)
- Korean - KR (477 KB)
- Portuguese - PT (477 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.3048 mL | 21.5239 mL | 43.0478 mL | 107.6195 mL |
| 5 mM | 0.8610 mL | 4.3048 mL | 8.6096 mL | 21.5239 mL | |
| 10 mM | 0.4305 mL | 2.1524 mL | 4.3048 mL | 10.7619 mL | |
| 15 mM | 0.2870 mL | 1.4349 mL | 2.8699 mL | 7.1746 mL | |
| 20 mM | 0.2152 mL | 1.0762 mL | 2.1524 mL | 5.3810 mL | |
| 25 mM | 0.1722 mL | 0.8610 mL | 1.7219 mL | 4.3048 mL | |
| 30 mM | 0.1435 mL | 0.7175 mL | 1.4349 mL | 3.5873 mL | |
| 40 mM | 0.1076 mL | 0.5381 mL | 1.0762 mL | 2.6905 mL | |
| 50 mM | 0.0861 mL | 0.4305 mL | 0.8610 mL | 2.1524 mL | |
| 60 mM | 0.0717 mL | 0.3587 mL | 0.7175 mL | 1.7937 mL | |
| 80 mM | 0.0538 mL | 0.2690 mL | 0.5381 mL | 1.3452 mL | |
| 100 mM | 0.0430 mL | 0.2152 mL | 0.4305 mL | 1.0762 mL |