Carboxypeptidase B2/CPB2 Protein, Mouse (HEK293, His)

Carboxypeptidase B2/CPB2 protein cleaves C-terminal arginine or lysine residues from active peptides, regulating their activities. It also down-regulates fibrinolysis by removing C-terminal lysine residues from degraded fibrin. CPB2 contributes to peptide signaling and fibrinolysis regulation. Carboxypeptidase B2/CPB2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Carboxypeptidase B2/CPB2 protein, expressed by HEK293 , with C-His labeled tag. The total length of Carboxypeptidase B2/CPB2 Protein, Mouse (HEK293, His) is 422 a.a., with molecular weight of ~60 kDa.

Carboxypeptidase B2/CPB2 protein functions by cleaving C-terminal arginine or lysine residues from biologically active peptides, such as kinins or anaphylatoxins, in the circulation, thereby regulating their activities. It also plays a role in down-regulating fibrinolysis by removing C-terminal lysine residues from partially degraded fibrin, which has been acted upon by plasmin. This protein thus contributes to the fine-tuning of peptide signaling and the regulation of fibrinolysis processes.

Mouse

HEK293

C-His

Q9JHH6 (M1-T422)

56373  [NCBI]

Approximately 60 kDa

Greater than 95% as determined by reducing SDS-PAGE

<1 EU/μg, determined by LAL method.