CCR8 Protein-VLP, Human (HEK293)

CCR8 Protein-VLP, Human (HEK293) is recommended for SPR analysis, animal immunization, ELISA, PK assay. If VLP control is required, it is recommended HY-P702775. May have binding signals with Anti-His antibodies.

The CCR8 Protein-VLP acts as a receptor for the chemokine CCL1/SCYA1/I-309, potentially regulating monocyte chemotaxis and thymic cell line apoptosis. It also serves as an alternative coreceptor with CD4 for HIV-1 infection, implicating its involvement in facilitating viral entry and infection. The interaction between CCR8 and CCL1 underscores its role in mediating cellular responses to this chemokine, suggesting a regulatory function in immune and inflammatory processes.

Immobilized Human CCR8 VLP at 5 μg/mL (100 μL/Well) on the plate. Dose response curvefor Anti-CCR8 Antibody, hFc Tag with the EC₅₀ of 6-7 ng/mL determined by ELISA.

Human

HEK293

Tag Free

P51685 (M1-L355)

1237  [NCBI]

Full Length

MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL

≥ 95%, as determined by HPLC.

Solution

Supplied as a 0.22 μm filtered solution of PBS, 300 mM L-arginine, pH 7.4. Notice: If you need it for immunization, water-soluble adjuvant is recommended.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.