S100A7A Protein, Human (P.pastoris, His)

The S100A7A protein plays potential roles in skin homeostasis, epidermal differentiation, and inflammation, suggesting its importance in skin health and disease. Its involvement in cellular functions makes it a key factor in diseases such as psoriasis, which is characterized by abnormal epidermal processes and inflammation. S100A7A Protein, Human (P.pastoris, His) is the recombinant human-derived S100A7A protein, expressed by P. pastoris , with N-His labeled tag.

For research use only. We do not sell to patients.
  • Species: Human
  • Source: P. pastoris
  • Storage:
    Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
  • Biological Activity
  • Technical Parameters
  • Product Properties
  • Documentation
  • Help & FAQs

Biological Activity

Description

The S100A7A protein plays potential roles in skin homeostasis, epidermal differentiation, and inflammation, suggesting its importance in skin health and disease. Its involvement in cellular functions makes it a key factor in diseases such as psoriasis, which is characterized by abnormal epidermal processes and inflammation. S100A7A Protein, Human (P.pastoris, His) is the recombinant human-derived S100A7A protein, expressed by P. pastoris , with N-His labeled tag.

Background

S100A7A Protein emerges as a potential player in epidermal differentiation and inflammation, suggesting a pivotal role in the intricate processes that contribute to skin homeostasis and immune response. Its implication in these cellular functions positions S100A7A as a potentially significant factor in the pathogenesis of diseases such as psoriasis, where aberrant epidermal differentiation and inflammation play key roles. The dual involvement in epidermal processes and inflammatory responses underscores the potential multifaceted impact of S100A7A on skin health and disease. Further exploration of its specific mechanisms and interactions may deepen our understanding of S100A7A's role in skin physiology and its potential implications in various pathological contexts, particularly those related to skin disorders and inflammatory conditions.

Technical Parameters

  • Species Human
  • Source P. pastoris
  • Tag N-His
  • Accession
  • Gene ID
  • Molecular Construction
    • N-term
    • His
    • S100A7A (S2-Q101)
      Accession # Q86SG5
    • C-term
  • Protein Length

    Full Length

  • Synonyms

    S100A7A; Protein S100-A7A; Prev. S100A7L1; S100 Calcium Binding Protein A7-Like 1; Prev. S100A15; S100 Calcium Binding Protein A15; S100A7f; S100 Calcium-Binding Protein A7A; S100 Calcium-Binding Protein A7-Like 1; NICE-2; S100 Calcium-Binding Protein A15

  • AA Sequence

    SNTQAERSIIGMIDMFHKYTGRDGKIEKPSLLTMMKENFPNFLSACDKKGIHYLATVFEKKDKNEDKKIDFSEFLSLLGDIAADYHKQSHGAAPCSGGSQ

  • Predicted Molecular Mass

    13.2 kDa

  • Purity

    ≥ 90%, as determined by reducing SDS-PAGE.

Product Properties

Appearance

Lyophilized powder.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.

Storage & Stability

Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Calculators

Reconstitution Calculator

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) Volume (to add to vial)
=
Mass (in vial) Mass (in vial)
÷
Desired Reconstitution Concentration Desired Reconstitution Concentration
Dilution Calculator

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

Concentration (start) Concentration (start)
×
Volume (start) Volume (start)
=
Concentration (final) Concentration (final)
×
Volume (final) Volume (final)
The Specific Activity Calculator Equation
  • Specific Activity (Unit/mg)
  • Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) Specific Activity (Unit/mg)
Unit/mg
= 106 ÷
Biological Activity (ED50) Biological Activity (ED50)
106 ÷
ng/mL
MOQ
Minimum order quantity
100 mg

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