S100A7A - S100 calcium binding protein A7A Gene

Also Known as NICE2; NICE-2; S100A15; S100A7f; S100A7L1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 338324

About S100A7A

Cytogenetic location: 1q21.3 Genomic coordinates (GRCh38): 1:153,416,520-153,423,222 (from NCBI)

This gene has 3 transcripts (splice variants), 285 orthologues and 21 paralogues. Low expression observed in reference dataset.

Summary

Enables protein self-association. Predicted to act upstream of or within inflammatory response. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

S100A7A Products (1)

mRNA Protein Name
NM_176823.4 NP_789793.1 protein S100-A7A

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IDA
IDA: Inferred from direct assay
21148126 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

S100A7A Protein Structure

S_100

S_100: S-100/ICaBP type calcium binding domain (7 - 45)

  • 0
  • 101 a.a.
Protein Preferred Names Protein Names

protein S100-A7A

  • S100 calcium-binding protein A15

S100A7A Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
S100A7A Q86SG5 S100A7L2 Homo sapiens Q5SY68
MAPPIT
32296183
Intra
S100A7A Q86SG5 S100A7L2 Homo sapiens Q5SY68
Y2H Array
32296183
Intra
S100A7A Q86SG5 S100A7L2 Homo sapiens Q5SY68
Y2H Prey Pooling
32296183
Intra
S100A7A Q86SG5 CLVS2 Homo sapiens Q5SYC1
Y2H Prey Pooling
32296183
Intra
S100A7A Q86SG5 CLVS2 Homo sapiens Q5SYC1
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant S100A7A Proteins

Cat. No. Product Name Accession Purity
HY-P71837 S100A7A Protein, Human (P.pastoris, His) Q86SG5 (S2-Q101) ≥ 90%, as determined by reducing SDS-PAGE.

Related Diseases

Diseases Alias
Psoriasis
Macular Degeneration, Age-Related, 13

  • Age Related Macular Degeneration 13

  • ARMD13

  • Macular Degeneration, Age-Related, 13, Susceptibility To

  • Macular Degeneration, Age-Related, Type 13
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12384 S100A7A Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus S100A7A RGD RGD:1593779
Mus musculus S100A7A MGD MGI:2687194