SARS-CoV-2 3CLpro/3C-like protease Protein

For research use only. We do not sell to patients.

Size	Price	Stock	Quantity
Free Sample		Apply now
5 μg	$95	In-stock	Estimated Time of Arrival: December 31
10 μg	$155	In-stock	Estimated Time of Arrival: December 31
20 μg	$235	In-stock	Estimated Time of Arrival: December 31
50 μg	$428	In-stock	Estimated Time of Arrival: December 31
100 μg		Get quote

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Biological Activity	Measured by its ability to cleave a fluorogenic peptide substrate Dabcyl-KTSAVLQSGFRKME-Edans and the specific activity is ≥1068.3 nmol/min/mg.
Species	Virus
Source	E. coli
Tag	Tag Free
Accession	YP_009725301 (S1-Q306)
Gene ID	43740578 [NCBI]
Molecular Construction	N-term SARS-CoV-2 3CLpro (S1-Q306) Accession # YP_009725301 C-term
Synonyms	3C-like protease; 3CL Protease; 3CL-Mpro; 3CL Pro; COVID-19; M Proteinase; Mpro
Molecular Weight	Approximately 33.8 kDa
Purity	Greater than 95% as determined by Tris-Bis PAGE.
Appearance	Solution
Formulation	Supplied as a 0.22 μm filtered solution of 25 mM HEPES, 2.5 mM DTT, 10% glycerol, pH 7.5.
Endotoxin Level	<1 EU/μg, determined by LAL method.
Reconstitution	N/A.
Storage & Stability	Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping	Shipping with dry ice.
Documentation	Select Batch: Data Sheet (231 KB) SDS (251 KB) COA (220 KB) Handling Instructions (2659 KB)

SARS-CoV-2 3CLpro/3C-like protease Protein Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Specific Activity (Unit/mg) = 10⁶ ÷ Biological Activity (ED₅₀)

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