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  3. Drug Derivative
  4. S-Adenosyl-L-ethionine

S-Adenosyl-L-ethionine is S-Adenosyl-L-methione analog. S-Adenosyl-L-ethionine is able to replace S-Adenosyl-L-methione during HydG catalysis. HydG can utilize S-Adenosyl-L-ethionine as an effective alternative cosubstrate to S-Adenosyl-L-methione under normal enzymatic turnover conditions, producing the Ω intermediate and allowing efficient catalytic turnover of substrate L-tyrosine.

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S-Adenosyl-L-ethionine

S-Adenosyl-L-ethionine Chemical Structure

CAS No. : 524-70-9

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S-Adenosyl-L-ethionine Related Antibodies

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Description

S-Adenosyl-L-ethionine is S-Adenosyl-L-methione analog. S-Adenosyl-L-ethionine is able to replace S-Adenosyl-L-methione during HydG catalysis. HydG can utilize S-Adenosyl-L-ethionine as an effective alternative cosubstrate to S-Adenosyl-L-methione under normal enzymatic turnover conditions, producing the Ω intermediate and allowing efficient catalytic turnover of substrate L-tyrosine[1].

Molecular Weight

412.46

Formula

C16H24N6O5S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

NC1=C(N=C2)C(N2[C@@H]3O[C@H](C[S+](CC)CC[C@H](N)C([O-])=O)[C@@H](O)[C@H]3O)=NC=N1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (242.45 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4245 mL 12.1224 mL 24.2448 mL
5 mM 0.4849 mL 2.4245 mL 4.8490 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.4245 mL 12.1224 mL 24.2448 mL 60.6119 mL
5 mM 0.4849 mL 2.4245 mL 4.8490 mL 12.1224 mL
10 mM 0.2424 mL 1.2122 mL 2.4245 mL 6.0612 mL
15 mM 0.1616 mL 0.8082 mL 1.6163 mL 4.0408 mL
20 mM 0.1212 mL 0.6061 mL 1.2122 mL 3.0306 mL
25 mM 0.0970 mL 0.4849 mL 0.9698 mL 2.4245 mL
30 mM 0.0808 mL 0.4041 mL 0.8082 mL 2.0204 mL
40 mM 0.0606 mL 0.3031 mL 0.6061 mL 1.5153 mL
50 mM 0.0485 mL 0.2424 mL 0.4849 mL 1.2122 mL
60 mM 0.0404 mL 0.2020 mL 0.4041 mL 1.0102 mL
80 mM 0.0303 mL 0.1515 mL 0.3031 mL 0.7576 mL
100 mM 0.0242 mL 0.1212 mL 0.2424 mL 0.6061 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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S-Adenosyl-L-ethionine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

S-Adenosyl-L-ethionine524-70-9Drug DerivativeDrug derivativeInhibitorinhibitorinhibit

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