(S)-Thalidomide-azetidine-O-Pip
(S)-Thalidomide-azetidine-O-Pip is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.
For research use only. We do not sell to patients.
- CAS No.: 2782051-26-5
- Formula: C21H24N4O5
- Molecular Weight:412.45
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All E3 Ligase Ligand-Linker Conjugates Isoforms
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Biological Activity
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Cereblon |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2782051-26-5
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Molecular Weight 412.45
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Formula C21H24N4O5
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SMILES
O=C1N(C(=O)C=2C1=CC(=CC2)N3CC(OC4CCNCC4)C3)[C@@H]5C(=O)NC(=O)CC5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)