23 Results for "

MAT2A-IN-2

" in MedChemExpress (MCE) Product Catalog:
Products (23)

23 Results for "MAT2A-IN-2" in MCE Product Catalog:

Cat. No.: HY-170421
CAS No.: 3025016-60-5
Research Areas:  

Cancer

MAT2A-IN-16 is a MAT2A inhibitor and inhibits cell proliferation of MTAP -/- HCT-116 cells (IC50: 20 nM) .
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Cat. No.: HY-170502
CAS No.: 2850245-72-4
Research Areas:  

Cancer

MAT2A-IN-19 (Compound I-3) is an inhibitor for methionine adenosyltransferase 2A (MAT2A) with an IC50 of 32.93 nM .
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Cat. No.: HY-183568
Research Areas:  

Cancer

MAT2A-IN-26 is an orally active MAT2A inhibitor with a human IC50 of 17.53 nM. MAT2A-IN-26 inhibits the enzymatic activity of MAT2A, thereby reducing the levels of S-adenosylmethionine (SAM) and symmetric dimethylarginine (sDMA). MAT2A-IN-26 inhibits the proliferation of MTAP-deficient cancer cells and induces anti-tumor efficacy in xenograft models. MAT2A-IN-26 can be used in non-small cell lung cancer research .
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