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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
27 Results for "
SERD
" in MedChemExpress (MCE) Product Catalog:
Products (27)
27 Results for "SERD" in MCE Product Catalog:
Cat. No.: HY-19822S1
Synonyms: RAD1901-d4-1
Cat. No.: HY-19822S2
Synonyms: RAD1901-d10
Cat. No.: HY-19822S3
Synonyms: RAD1901-d6
Cat. No.: HY-125263B
CAS No.: 1443752-77-9
Target:
Research Areas:
(R)-OP-1074 is an isomer of OP-1074 (HY-125263) and can serve as a control compound in experiments. OP-1074, a pure anti-estrogen drug, is a selective ER degrader (PA-SERD) with specific anti-estrogenic activity against ERα and ERβ, inhibiting 17β-estradiol (E2)-stimulated transcription with IC50 values of 1.6 and 3.2 nM, respectively.
Cat. No.: HY-111486R
CAS No.: 2135600-76-7
Research Areas:
LSZ-102 (Standard) is the analytical standard of LSZ-102 (HY-111486). This product is intended for research and analytical applications. LSZ-102 is a potent, orally bioavailable, selective estrogen receptor degrader (SERD) with an IC50 value of 0.2 nM.
Cat. No.: HY-19822S4
Synonyms: RAD1901-d5
Cat. No.: HY-124627
CAS No.: 1799430-91-3
Target:
Research Areas:
THIQ-40 is a tetrahydroisoquinoline-based, orally active, and selective estrogen receptor ERα degrader (SERD) (IC50=17 nM), with antitumor efficacy. THIQ-40 possesses functional ERα antagonistic activity, promotes ERα degradation and forms stable ERαLBD complexes. THIQ-40 shows the characteristic of rapid racemization in multi-species plasma. THIQ-40 can be widely applied to studies on the relevant mechanisms and drug development of ERα-positive breast cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
