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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
27 Results for "
phase separation
" in MedChemExpress (MCE) Product Catalog:
Products (27)
27 Results for "phase separation" in MCE Product Catalog:
Cat. No.: HY-176048
CAS No.: 152813-63-3
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ChEMBL22003 is a potential phase separation modulator of ARV7 that can bind to the ARV7 binding sites. ChEMBL22003 has potential for use in the research of prostate cancer .
Cat. No.: HY-116664
CAS No.: 1431362-93-4
DPQZ is an anti-tubulin agent that inhibits cell separation and induces cell cycle arrest at the G2/M phase. In addition, DPQZ induces caspase-dependent apoptosis of HSC-3 cells by inhibiting Ras/Raf and activating MAP kinase. DPQZ can be used in the study of oral cancer .
Cat. No.: HY-W008952
CAS No.: 81741-28-8
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Tributyltetradecyl phosphonium chloride is a quaternary phosphonium salt cation. Tributyltetradecyl phosphonium chloride can form an acidic aqueous biphasic system with acid and water, exhibits temperature-induced phase separation behavior with a lower critical solution temperature, enables the partitioning of Co 2+, Fe 3+, Pt 4+ and Ni 2+ between the two phases, and also promotes the separation of Co 2+ and Ni 2+ .
Cat. No.: HY-187172
CAS No.: 2060801-74-1
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BDF34019555 is a blood-brain barrier-permeable binder targeting the conserved region (amino acid residues 320-340) of TDP-43, with a Kd of 10.4 μM for full-length TDP-43 and 7.8 μM for the CR polypeptide, respectively. BDF34019555 binds to the conserved α-helical region of TDP-43 in a Trp334-dependent manner, inhibits liquid-liquid phase separation, aggregation and mitochondrial localization of TDP-43, restores mitochondrial function, reduces cytoplasmic and insoluble TDP-43 levels, without affecting the splicing activity of TDP-43. BDF34019555 exerts neuroprotective effects, alleviates motor neuron loss and improves motor neuron function. BDF34019555 can be used in studies related to amyotrophic lateral sclerosis .
Cat. No.: HY-W673649
CAS No.: 108392-10-5
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N-Oleyl-sphingomyelin is a bilayer property lipid modulator with affinity for cholesterol bilayers. N-Oleyl-sphingomyelin reduces the amount of cholesterol required for liquid-ordered phase formation and enhances the cholesterol tolerance of membrane structures. N-Oleyl-sphingomyelin can be used in studies related to membrane lipid phase separation and lipid raft structures .
Cat. No.: HY-P11504
CAS No.: 3109821-26-0
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Cat. No.: HY-D3576
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AF532 C5 Maleimide is a Fluorescent dye used for protein labeling. AF532 C5 Maleimide covalently binds to thiol groups via its maleimide moiety. AF532 C5 Maleimide can label VASP to support visualization studies in phase separation and focused actin polymerization experiments .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
