186 Results for "

CD4 T

" in MedChemExpress (MCE) Product Catalog:
Products (186)

186 Results for "CD4 T" in MCE Product Catalog:

Cat. No.: HY-P3554
CAS No.: 129988-00-7
Target:  

HIV

Research Areas:  

Infection

Carbomethoxycarbonyl-D-Pro-D-Phe-OBzl (compound (CPF(LL)) is an HIV-1 inhibitor. Carbomethoxycarbonyl-D-Pro-D-Phe-OBzl interacts with gp120 to block gp120 binding to CD4 and preserve CD4-dependent T cell function .
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Cat. No.: HY-P10593
CAS No.: 126779-14-4
Research Areas:  

Cancer

Influenza A NP (383-391) (HLA-B27) is a peptide sequence derived from tetanus toxin. Influenza A NP (383-391) (HLA-B27) is a broadly immunogenic CD4+ T helper cell epitope that enhances CD8+ cytotoxic T lymphocyte (CTL) responses. Influenza A NP (383-391) (HLA-B27) can be used in breast cancer research .
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Cat. No.: HY-P991436
Synonyms: BMS-986415

Research Areas:  

Cancer

DF6002 (BMS-986415) is a monovalent IL-12 immunoglobulin Fc fusion protein. DF6002 can promote sustained IFN-γ responses while reducing toxicity. DF6002 binds specifically to IL-12R on CD4 + T cells, CD8 + T cells, NK cells, and B cells. DF6002 can be used for the research of solid tumors .
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Cat. No.: HY-P991655

Target:  

IFNAR HIV

Research Areas:  

Infection Inflammation/Immunology

AGS-009 is a humanized monoclonal neutralising antibody targeting IFN-α. AGS-009 significantly reduces activated lymphocytes, such as CD4 + and CD8 + T cells as well as B cells in SIV infection rhesus macaque models. AGS-009 can be used for autoimmune diseases like systemic lupus erythematosus (SLE) and HIV infections research .
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Cat. No.: HY-159123
Target:  

MAP4K

Research Areas:  

Cancer

KHK-6 is an inhibitor for serine/threonine kinase hematopoietic progenitor kinase 1 (HPK 1) with an IC50 of 20 nM. KHK-6 enhances CD3/CD28-induced cytokine production, enhances CD69, CD25 and HLA-DR markers on CD4+ and CD8+ T cells, and enhances T cell-mediated killing activity of SKOV3 and A549 cells .
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Cat. No.: HY-P11122
CAS No.: 861243-71-2
Research Areas:  

Inflammation/Immunology

MSP-1 P2 is a synthetic peptide of merozoite surface protein-1 (MSP-1). MSP-1 P2 stimulates umbilical cord blood lymphocytes to produce IFN-γ and IL-13, and this immune response is primarily mediated by CD4+ T cells. MSP-1 P2 can be used as a specific antigen stimulus to detect T cell responses and cytokine levels .
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Cat. No.: HY-P10382
Target:  

MHC

Research Areas:  

Inflammation/Immunology

M133 peptide is a coronavirus-specific CD4 T cell epitope. M133 peptide is immunodominant in mice infected with the neurotropic coronavirus (the JHM strain of mouse hepatitis virus). M133 peptide forms a complex with MHC II molecules, which is recognized by specific TCRs, thereby activating CD4 T cells .
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Cat. No.: HY-P2561
CAS No.: 1286245-45-1
Target:  

Influenza Virus

Research Areas:  

Infection Inflammation/Immunology

Influenza Matrix Protein (61-72) is a peptide fragment derived from matrix protein of influenza viruses, corresponds to amino acids 61-72. Influenza Matrix Protein (61-72) is a specific epitope which can induce CD4 + T-cell response .
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Cat. No.: HY-176280
CAS No.: 2557232-80-9
SARS-CoV-2-IN-115 (Compound 3e) is a SARS-CoV-2 inhibitor. SARS-CoV-2-IN-115 has potent antiviral activity against SARS-CoV-2 in infected Calu-3 cells (EC50: 1.7  μM). SARS-CoV-2-IN-115 effectively inhibits the activity of human dihydroorotate dehydrogenase (HsDHODH) (IC50: 1.5  μM). SARS-CoV-2-IN-115 preserves immune response without antiproliferative effects on CD4 T cells .
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Cat. No.: HY-P5930
Synonyms: MDM2 32-46
Target:  

Ligands for E3 Ligase

Research Areas:  

Cancer

HOXB7 8–25 (MDM2 32-46) is an MDM2-derived peptide epitope and can elicit antigen-specifc and tumor-reactive CD4 + T cell responses .
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Cat. No.: HY-174765
Target:  

mRNA

Research Areas:  

Inflammation/Immunology

Human CCL18 mRNA encodes the human C-C motif chemokine ligand 18 (CCL18) protein, a cytokine that displays chemotactic activity for naive T cells, CD4+ and CD8+ T cells and nonactivated lymphocytes, but not for monocytes or granulocytes. CCL18 may play a role in both humoral and cell-mediated immunity responses.
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Cat. No.: HY-P991318

Target:  

Mucin

Research Areas:  

Cancer

AR20.5 is a human monoclonal antibody (mAb) targeting MUC1. AR20.5 increases the number of activated CD8 T cells, CD3+CD4−CD8−(DN) T cells, and mature dendritic cells in pancreatic tumor-bearing mice. AR20.5 can be used in anti-pancreatic cancer immunity research .
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Cat. No.: HY-15440AR
CAS No.: 864953-29-7
Synonyms: BMS-663068 (Standard)
Target:  

Reference Standards HIV

Research Areas:  

Infection

Fostemsavir (Standard) is the analytical standard of Fostemsavir. This product is intended for research and analytical applications. Fostemsavir (BMS-663068) is the phosphonooxymethyl prodrug of BMS-626529. Fostemsavir (BMS-663068) is a novel attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4 + T cells.
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Cat. No.: HY-174754
Target:  

mRNA

Research Areas:  

Inflammation/Immunology

Human CCL28 mRNA encodes the human C-C motif chemokine ligand 28 (CCL28) protein, a cytokine that displays chemotactic activity for resting CD4 or CD8 T cells and eosinophils. CCL28 may play a role in the physiology of extracutaneous epithelial tissues, including diverse mucosal organs.
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Cat. No.: HY-119347R
CAS No.: 41365-32-6
Cirsilineol (Standard) is the analytical standard of Cirsilineol. This product is intended for research and analytical applications. Cirsilineol, a natural flavone compound, selectively inhibits IFN-γ/STAT1/T-bet signaling in intestinal CD4+ T cells. Cirsilineol has potent immunosuppressive and anti-tumor properties. Cirsilineol significantly ameliorates trinitro-benzene sulfonic acid (TNBS)-induced T-cell-mediated experimental colitis in mice .
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Cat. No.: HY-15440AS
Synonyms: BMS-663068-d8
Fostemsavir-d8 (BMS-663068-d8) is deuterium labeled Fostemsavir. Fostemsavir (BMS-663068) is the phosphonooxymethyl prodrug of BMS-626529. Fostemsavir (BMS-663068) is a novel attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4 + T cells.
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Cat. No.: HY-15440BR
CAS No.: 864953-39-9
Synonyms: BMS-663068 Tris (Standard)
Target:  

HIV Reference Standards

Research Areas:  

Infection

Fostemsavir Tris (Standard) is the analytical standard of Fostemsavir Tris. This product is intended for research and analytical applications. Fostemsavir Tris (BMS-663068 (Tris)) is the phosphonooxymethyl proagent of BMS-626529. Fostemsavir Tris (BMS-663068 (Tris)) is a novel attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T cells.
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Cat. No.: HY-15091
CAS No.: 170368-04-4
Synonyms: LF-150195
Target:  

Endogenous Metabolite

Research Areas:  

Neurological Disease

Anisperimus (LF-150195) is an immunosuppressant with the activity of enhancing activation-induced T cell death. Anisperimus enhances the sensitivity of T cells to anti-CD95 antibodies and other inducers by promoting the activation of caspase-8 and caspase-10 at the level of the death-inducing signaling complex (DISC). Anisperimus also promotes the development of Foxp3-expressing regulatory CD4 T cells, thereby preventing central nervous system autoimmunity .
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Cat. No.: HY-137618B
CAS No.: 80902-29-0
Target:  

HIV

Research Areas:  

Others

Rp-dGTPαS is the nucleotide substrate of SAMHD1 and is one of the enantiomers of the dNTPαS nucleotide. SAMHD1 is an essential regulator of cellular dNTPs that limits virus (HIV-1, etc.) replication in the CD4+ myeloid lineage and resting T cells. The SAMHD1 tetrameric complex catalyzes the hydrolysis of Rp-dGTPαS into 2'-deoxynucleosides and triphosphates .
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Cat. No.: HY-173000
CAS No.: 3053241-01-0
Target:  

Apoptosis Ferroptosis STAT

Research Areas:  

Cancer

STAT3-IN-40 (Compound 8b) is an anti-cancer agent. STAT3-IN-40 can trigger the immune responses of CD4+ and CD8+ T lymphocytes and induce ferroptosis and apoptosis of tumor cells by inhibiting the expression and phosphorylation of STAT3. STAT3-IN-40 can be used in the research of chemoimmunotherapeutic agents for cancer .
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