3053241-01-0
Chemical Structure
STAT3-IN-40
- CAS No.: 3053241-01-0
- Formula:C32H34ClN5O12Pt
- Molecular Weight:911.18
InChIKey: YDDXOZCLGHPRGS-JOHNBCPTSA-J
SMILES: O=C(N1C/C(C(/C(C1)=C/C2=CC=C(C=C2)[N+]([O-])=O)=O)=C\C3=CC=C(C=C3)[N+]([O-])=O)CCCC([O-][Pt+4]45([NH2][C@@]6([H])[C@](CCCC6)([H])[NH2]4)([O-]C(C([O-]5)=O)=O)[Cl-])=O
Biological Activity: STAT3-IN-40 (Compound 8b) is an anti-cancer agent. STAT3-IN-40 can trigger the immune responses of CD4+ and CD8+ T lymphocytes and induce ferroptosis and apoptosis of tumor cells by inhibiting the expression and phosphorylation of STAT3. STAT3-IN-40 can be used in the research of chemoimmunotherapeutic agents for cancer[1].
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STAT3-IN-40 | STAT3-IN-40 (Compound 8b) is an anti-cancer agent. STAT3-IN-40 can trigger the immune responses of CD4+ and CD8+ T lymphocytes and induce ferroptosis and apoptosis of tumor cells by inhibiting the expression and phosphorylation of STAT3. STAT3-IN-40 can be used in the research of chemoimmunotherapeutic agents for cancer. | |||||||||||||||||||||
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Keywords
