2557232-80-9

SARS-CoV-2-IN-115 Chemical Structure
2557232-80-9

Chemical Structure

SARS-CoV-2-IN-115

  • No. CAS: 2557232-80-9
  • Formula:C16H14N2O
  • Molecular Weight:250.30

SMILES: CC(NC1=CC=C(C=C1)C#CC2=CC(N)=CC=C2)=O

Biological Activity: SARS-CoV-2-IN-115 (Compound 3e) is a SARS-CoV-2 inhibitor. SARS-CoV-2-IN-115 has potent antiviral activity against SARS-CoV-2 in infected Calu-3 cells (EC50: 1.7  μM). SARS-CoV-2-IN-115 effectively inhibits the activity of human dihydroorotate dehydrogenase (HsDHODH) (IC50: 1.5  μM). SARS-CoV-2-IN-115 preserves immune response without antiproliferative effects on CD4 T cells [1].

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HY-176280 		SARS-CoV-2-IN-115 SARS-CoV-2-IN-115 (Compound 3e) is a SARS-CoV-2 inhibitor. SARS-CoV-2-IN-115 has potent antiviral activity against SARS-CoV-2 in infected Calu-3 cells (EC50: 1.7  μM). SARS-CoV-2-IN-115 effectively inhibits the activity of human dihydroorotate dehydrogenase (HsDHODH) (IC50: 1.5  μM). SARS-CoV-2-IN-115 preserves immune response without antiproliferative effects on CD4 T cells .
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