2 Results for "

(3S,4R)-ME-344

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "(3S,4R)-ME-344" in MCE Product Catalog:

Cat. No.: HY-112749B
CAS No.: 1374524-84-1
(3S,4R)-ME-344 is the (3S,4R)-enantiomer of ME-344 (HY-112749). ME-344 is a mitochondrial Heme oxygenase 1 (HO-1) inhibitor. ME-344 specifically binds and alters HO-1 structure, and increases HO-1 translocation from the rough endoplasmic reticulum to mitochondria, but only in drug-sensitive cells (such as H460 and SHP-77 cells). ME-344 decreases mitochondrial ATP production and induces ROS, with subsequent disruption of redox homeostasis and mitochondrial function. ME-344 has significant antitumor activity, and can be used for cancers like breast cancer research .
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Cat. No.: HY-P1888
CAS No.: 1201633-99-9
Research Areas:  

Cardiovascular Disease

HIF-1 alpha (556-574) is a short hypoxia-inducible factor-1 (HIF-1) 19 residues fragment. HIF-1 functions as master regulator of response to oxygen homeostasis .
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