1 Result for "

(R)-Acenocoumarol

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "(R)-Acenocoumarol" in MCE Product Catalog:

Cat. No.: HY-121814A
CAS No.: 66556-77-2
Synonyms: (R)-Acenocoumarin; (R)-Nicoumalone
Target:  

VD/VDR

Research Areas:  

Cardiovascular Disease

(R)-Acenocoumarol ((R)-Acenocoumarin; (R)-Nicoumalone) is a short-acting and orally active anticoagulant, like Warfarin (HY-B0687), works by inhibiting vitamin K epoxide reductase. (R)-Acenocoumarol has a greater in vivo anticoagulant potency than Warfarin. (R)-Acenocoumarol has a single chiral center that produces two different enantiomeric forms. (R)-Acenocoumarol has a longer plasma elimination half-life (6.6 h) and a slower plasma clearance rate (1.9 L/h) than the (S)-enantiomer, resulting in a stronger in vivo anticoagulant effect.
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