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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1 Result for "
AT877 hydrochloride semihydrate
" in MedChemExpress (MCE) Product Catalog:
Products (1)
1 Results for "AT877 hydrochloride semihydrate" in MCE Product Catalog:
Cat. No.: HY-10341B
CAS No.: 186694-02-0
Synonyms: HA-1077 hydrochloride semihydrATe; AT877 hydrochloride semihydrATe
Fasudil (HA-1077; AT877) hydrochloride semihydrate is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an Ki of 0.33 μM for ROCK1, IC50s of 0.158 μM and 4.58 μM, 12.30 μM, 1.650 μM for ROCK2 and PKA, PKC, PKG, respectively. Fasudil hydrochloride semihydrate is also a potent Ca 2+ channel antagonist and vasodilator .
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