Search Result

Results for "

CHO

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (17) AAK1 (1) ADC Antibody (3) ADC Linker (2) ADC Payload (1) Adenosine Receptor (19) Adenylate Cyclase (3) Adrenergic Receptor (23) Akt (2) Amino Acid Decarboxylase (1) Amylin Receptor (1) Amyloid-β (5) Anaplastic lymphoma kinase (ALK) (1) Androgen Receptor (3) Angiotensin Receptor (1) ANGPTL (2) Antibiotic (1) Antifolate (2) Apelin Receptor (APJ) (1) Apoptosis (45) Aquaporin (1) ATP-binding cassette (ABC) transporters (1) Autophagy (4) Bacterial (8) Bcl-2 Family (3) Beta-lactamase (1) Beta-secretase (3) Biochemical Assay Reagents (39) Bradykinin Receptor (2) c-Fms (1) c-Kit (1) c-Met/HGFR (1) C-type Lectin-like Receptors (CTLRs) (2) Cadherin (5) Calcium Channel (5) CaMK (1) Cannabinoid Receptor (6) Casein Kinase (2) Caspase (31) Cathepsin (3) CCR (10) CD19 (3) CD20 (1) CD22 (1) CD276/B7-H3 (1) CD28 (1) CD3 (2) CD47 (1) CD73 (1) CGRP Receptor (2) Chloride Channel (1) Claudin (1) Complement System (3) COX (16) CRAC Channel (1) CRFR (3) CTLA-4 (1) CXCR (10) Cyclin G-associated Kinase (GAK) (1) Cytochrome P450 (4) Discoidin Domain Receptor (1) DNA/RNA Synthesis (9) Dopamine Receptor (8) Drug Derivative (3) Drug Intermediate (2) Drug Metabolite (11) Drug-Linker Conjugates for ADC (1) Dynamin (1) E3 Ligase Ligand-Linker Conjugates (10) Early 2 Factor (E2F) (1) EGFR (13) Emopamil Binding Protein (1) Endogenous Metabolite (22) Endothelin Receptor (5) Environmental Pollutants (3) Ephrin Receptor (1) Epigenetic Reader Domain (1) ERK (6) Estrogen Receptor/ERR (2) Eukaryotic Initiation Factor (eIF) (2) FAAH (1) Factor VIII (1) Fc Receptor (FcR) (3) Ferroportin (2) FGFR (6) FKBP (2) FLT3 (1) Fluorescent Dye (2) Formyl Peptide Receptor (FPR) (1) Free Fatty Acid Receptor (5) FXR (1) G protein-coupled Bile Acid Receptor 1 (11) G Protein-coupled Receptor Kinase (GRK) (1) G2A (GPR132) (1) GABA Receptor (9) Gap Junction Protein (1) GCGR (6) GHSR (2) GLP Receptor (7) GLUT (1) Glycosidase (1) GlyT (1) GPR35 (1) GPR6 (1) GPR84 (1) GPR88 (1) GSK-3 (1) Guanylate Cyclase (2) HBV (1) HCV (3) Hepcidin (1) Herbicide (2) Histamine Receptor (1) Histone Acetyltransferase (1) Histone Methyltransferase (2) HIV (1) HSP (1) Human leukocyte immunoglobulin (Ig)-like receptors (LILR) (1) IFNAR (1) iGluR (8) Influenza Virus (2) Insulin Receptor (1) Integrin (10) Interleukin Related (30) IRE1 (1) Isotope-Labeled Compounds (15) Kallikrein (1) Kisspeptin Receptor (1) KMO (1) LDLR (3) Leukotriene Receptor (1) Ligands for E3 Ligase (1) Liposome (10) Lipoxygenase (1) LPL Receptor (8) LXR (1) mAChR (10) MCHR1 (GPR24) (2) Melanocortin Receptor (3) Melanopsin Receptor (1) Melatonin Receptor (8) Mesothelin (1) mGluR (8) MHC (1) Microtubule/Tubulin (2) Mitogen- and Stress-Activated Protein Kinase (MSK) (2) MMP (1) Motilin Receptor (1) mTOR (2) Myosin (1) Na+/Ca2+ Exchanger (1) NAMPT (1) Natriuretic Peptide Receptor (NPR) (1) Neurokinin Receptor (8) Neuropeptide FF Receptor (1) Neuropeptide Y Receptor (5) Neurotensin Receptor (4) NF-κB (9) NOD-like Receptor (NLR) (1) Notch (3) Nucleoside Antimetabolite/Analog (4) OGT (2) Opioid Receptor (25) Orexin Receptor (OX Receptor) (9) Orphan GPCR (3) Oxytocin Receptor (1) P-glycoprotein (1) P2Y Receptor (1) p38 MAPK (7) PACAP Receptor (2) PAI-1 (1) Parasite (2) PARP (8) PCSK9 (3) PD-1/PD-L1 (8) PDGFR (2) PERK (1) Phosphatase (2) Phosphodiesterase (PDE) (1) Phospholipase (1) Phosphorylase (1) PI3K (3) PI4K (1) PKA (8) Potassium Channel (6) PPAR (1) Prolyl Endopeptidase (PREP) (1) Prostaglandin Receptor (5) PROTAC Linkers (14) PROTACs (2) Proteasome (7) Protein Prenyltransferase (1) Pyroptosis (1) Radionuclide-Drug Conjugates (RDCs) (1) Ras (1) Reactive Oxygen Species (ROS) (1) Reference Standards (36) RET (1) RIP kinase (1) ROR (1) SARS-CoV (6) Scavenger Receptor Class B type I (SR-BI） (1) Ser/Thr Protease (7) Serotonin Transporter (2) SGLT (2) Sigma Receptor (2) Small Interfering RNA (siRNA) (1) Smo (1) Sodium Channel (10) Sodium Phosphate Cotransporter (1) Somatostatin Receptor (4) Src (1) Steroid Sulfatase (1) TGF-beta/Smad (4) TGF-β Receptor (4) Thrombin (2) TNF Receptor (14) Toll-like Receptor (TLR) (2) Topoisomerase (2) Transmembrane Glycoprotein (28) TREM receptor (1) Trk Receptor (4) TRP Channel (9) Tyrosinase (3) ULK (1) Urotensin Receptor (4) Vasopressin Receptor (1) VEGFR (11) Wnt (3) β-catenin (2) γ-secretase (3)
By Research Areas:	Cancer (166) Cardiovascular Disease (39) Endocrinology (39) Infection (25) Inflammation/Immunology (410) Metabolic Disease (54) Neurological Disease (177)
Click Chemistry:	PROTAC Synthesis (1) Azide (3) Alkynes (1)
Oligonucleotides:	Adenosine (1) Pegylated Lipids (7) Nucleoside Analogs (1) Mouse Pre-designed siRNA Sets (1) Polymers (5) Cholesterol (3) siRNAs (1)

725

Inhibitors & Agonists

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

MCE Kits

382

Inhibitory Antibodies

Natural
Products

166

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Oligonucleotides

GMP Molecules

Z-FY-CHO 5+ Cited Publications Z-Phe-Tyr-CHO	Cathepsin	Neurological Disease Metabolic Disease
Z-FY-CHO (Z-Phe-Tyr-CHO) is a potent and specific cathepsin L (CTSL) inhibitor .

Ac-DEVD-CHO Maximum Cited Publications 46 Publications Verification	Caspase	Cancer
Ac-DEVD-CHO is a Caspase-3 inhibitor with a K_i value of 230 pM.

*N3-Cho* bromide** 1 Publications Verification Azido-CHOline bromide	Biochemical Assay Reagents	Others
N3-Cho (Azido-choline) bromide is a click chemistry reagent containing an azide group that can be used in the synthesis of cell membrane structures .

Ac-IEPD-CHO 1 Publications Verification	Caspase	Cancer
Ac-IEPD-CHO is a reversible granzyme B inhibitor with a K_i of 80 nM . Ac-IEPD-CHO is also a caspase-8 inhibitor .

Ac-YVAD-CHO L-709049	Interleukin Related Apoptosis Caspase	Inflammation/Immunology
Ac-YVAD-CHO (L-709049) is a potent, reversible, specific tetrapeptide interleukin-lβ converting enzyme (ICE) inhibitor with mouse and human K_i values of 3.0 and 0.76 nM. Ac-YVAD-CHO is also a caspase-1 inhibitor. Ac-YVAD-CHO can suppress the production of mature IL-lβ .

Ac-LEVD-CHO 1 Publications Verification	Caspase	Cancer
Ac-LEVD-CHO is a caspase-4 inhibitor. Ac-LEVD-CHO is a peptide with the sequence of Ac-Leu-Glu-Val-Asp-al .

Ac-IETD-CHO	Apoptosis	Cancer
Ac- IETD- CHO is a potent, reversible inhibitor of granzyme B and caspase-8. Ac- IETD- CHO inhibits Fas-mediated apoptotic cell death, hemorrhage, and liver failure. Ac- IETD- CHO also inhibits cytotoxic T lymphocytes induced cell death .

Z-LLNle-CHO Z-Leu-Leu-Nle-CHO; GSII	γ-secretase Proteasome Apoptosis	Cancer
Z-LLNle-CHO (Z-Leu-Leu-Nle-CHO) is a γ-secretase inhibitor I. Z-LLNle-CHO induces caspase and ROS-dependent apoptosis by blocking the Akt-mediated pro-survival pathway. Z-LLNle-CHO can be used in cancer research, such as breast cancer and leukaemia .

*Ac-VEID-CHO* TFA**	Caspase	Neurological Disease
Ac-VEID-CHO (TFA) is a peptide-derived caspase inhibitor and has potency of inhibition for Caspase-6, Caspase-3 and Caspase-7 with IC₅₀ values of 16.2 nM, 13.6 nM and 162.1 nM, respectively. Ac-VEID-CHO (TFA) can be used for the research of neurodegenerative conditions including Alzheimer’s and Huntington’s disease .

Z-Pro-Pro-CHO	Prolyl Endopeptidase (PREP) Parasite	Infection
Z-Pro-Pro-CHO is a potent inhibitor of prolyl oligopeptidase (POP), with extremely high affinity for human prolyl oligopeptidase (HsPOP) (IC₅₀=0.012 μM), and it also effectively inhibits the activity of Schistosoma mansoni prolyl oligopeptidase (SmPOP) (IC₅₀=0.16 μM). Z-Pro-Pro-CHO does not block the phosphorylation of ERK or the production of TNF-α or IFN-γ in immune cells from presensitized mice, nor does it induce harmful phenotypes in cultured Schistosoma mansoni schistosomula. Z-Pro-Pro-CHO only partially inhibits epithelial cell wound healing at extremely high concentrations. Z-Pro-Pro-CHO finds wide application in studies related to schistosomiasis .

DSPE-PEG2000-CHO	Liposome	Others
DSPE-PEG2000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG2000-CHO can be used for drug delivery .

BocNH-PEG4-CH2CHO	PROTAC Linkers	Cancer
BocNH-PEG4-CH2CHO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

Cathepsin L-IN-4 1-Naphthalenesulfonyl-Ile-Trp-CHO	Cathepsin	Others
Cathepsin L-IN-4 is an inhibitor of cathepsin L with IC₅₀ at nanomolar concentrations .

IETD-CHO Caspase-8-IN-1	Caspase	Others
IETD-CHO (Caspase-8-IN-1) is a potent caspase-8 inhibitor .

SP3CHO	Drug Metabolite	Cancer
SP3CHO is an active metabolite generated by the metabolism of SP3N in cell culture by the action of amine oxidase. SP3CHO can induce polyubiquitination of specific proteins by recruiting the SCFFBXO22 E3 ligase complex. SP3CHO can be used in cancer therapy research .

DSPE-PEG5000-CHO	Liposome	Others
DSPE-PEG5000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG5000-CHO can be used for drug delivery .

DSPE-PEG1000-CHO	Liposome	Others
DSPE-PEG1000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG1000-CHO can be used for drug delivery .

m-PEG6-CH2CH2CHO	ADC Linker PROTAC Linkers	Cancer
m-PEG6-CH2CH2CHO is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG6-CH2CH2CHO is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Ac-LEHD-CHO	Apoptosis Caspase	Cancer
Ac-LEHD-CHO is an inhibitor for caspase 8/9. Ac-LEHD-CHO prevents GalN/TNF-α-induced hepatotoxicity and hepatocyte apoptosis .

*Biotin-DEVD-CHO* TFA**	Caspase Orexin Receptor (OX Receptor)	Others
Biotin-DEVD-CHO (TFA) is a biotin-conjugated form of the caspase-3 and -7 inhibitor – Ac-DEVD-CHO. Biotin-DEVD-CHO (TFA) can be used for affinity purification of the active caspase-3, -6, -7, and -8. Biotin-DEVD-CHO (TFA) can detect the active caspase-3 in vitro .

*YVAD-CHO* TFA**	Caspase Interleukin Related	Neurological Disease Inflammation/Immunology
YVAD-CHO TFA is an interleukin-1β converting enzyme (ICE, caspase 1) inhibitor (K_i: 0.76 nM). YVAD-CHO TFA inhibits mature IL-1β production. YVAD-CHO TFA partially delays motoneurone death in lesioned facial nerve mice .

Biotin-DEVD-CHO	Caspase	Others
Biotin-DEVD-CHO can be used for affinity labeling of Caspase-8 following in vitro caspase cleavage .

YVAD-CHO	Interleukin Related Caspase	Neurological Disease Inflammation/Immunology
YVAD-CHO is an interleukin-1β converting enzyme (ICE, caspase 1) inhibitor (K_i: 0.76 nM). YVAD-CHO inhibits mature IL-1β production. YVAD-CHO partially delays motoneurone death in lesioned facial nerve mice .

Ac-VEID-CHO	Caspase	Neurological Disease
Ac-VEID-CHO is a peptide-derived caspase inhibitor and has potency of inhibition for Caspase-6, Caspase-3 and Caspase-7 with IC₅₀ values of 16.2 nM, 13.6 nM and 162.1 nM, respectively. Ac-VEID-CHO also inhibits VEIDase activity an IC₅₀ value of 0.49 µM. Ac-VEID-CHO can be used for the research of neurodegenerative conditions including Alzheimer’s and Huntington’s disease .

*Ac-YVAD-CHO* acetate** L-709049 acetate	Interleukin Related Caspase Apoptosis	Inflammation/Immunology
Ac-YVAD-CHO (L-709049) acetate is a potent, reversible, specific tetrapeptide interleukin-lβ converting enzyme (ICE) inhibitor with mouse and human K_i values of 3.0 and 0.76 nM. Ac-YVAD-CHO acetate is also a caspase-1 inhibitor. Ac-YVAD-CHO acetate can suppress the production of mature IL-lβ .

mPEG5000-CHO mPEG5000-Aldehyde	Biochemical Assay Reagents	Others
mPEG5000-CHO participates in the formation of a three-dimensional porous scaffold which carries active substances to form a delivery vehicle. The -CHO functional group interacts with the -NH2 functional group of the chitosan chain to form a glutaraldehyde-type adduct to functionalize mPEG. This functionalization and cross-linking can affect the rigidity of the delivery system, allowing slow release of the cross-linked conjugate system.

Desamino lenalidomide-azetidine-CHO	E3 Ligase Ligand-Linker Conjugates	Cancer
Desamino lenalidomide-azetidine-CHO is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.

Ac-VAD-CHO Ac-Val-Ala-Asp-CHO	Caspase	Cancer
Ac-VAD-CHO (Ac-Val-Ala-Asp-CHO) is a pan-caspase inhibitor. Ac-VAD-CHO inhibits dissipation of MMP and cytochrome c release in hypoxia-exposed cells .

Ac-AAVALLPAVLLALLAP-DEVD-CHO DEVD-CHO-CPP 32	Caspase	Cancer
Ac-AAVALLPAVLLALLAP-DEVD-CHO (DEVD-CHO-CPP 32) is a potent and reversible caspase-3 inhibitor .

Z-LLF-CHO Z-Leu-Leu-Phe-CHO	Proteasome	Cancer
Z-LLF-CHO (Z-Leu-Leu-Phe-CHO) is a potent inhibitor of the chymotrypsin-like activity of the pituitary multicatalytic proteinase complex (K_i = 460 nM). Z-LLF-CHO is also a NF-κB nuclear translocation inhibitor .

Ac-LETD-CHO	Caspase	Cancer
Ac-LETD-CHO is a caspases 8 inhibitor. Ac-LETD-CHO has specific inhibition to casp-8 with an IC₅₀ value of 6.71 nM. Ac-LETD-CHO can be used for the research of anticancer .

Ac-DMQD-CHO	Caspase Apoptosis	Neurological Disease
Ac-DMQD-CHO is a selective inhibitor for caspase 3, with IC₅₀ of 39 nM. Ac-DMQD-CHO reduces apoptosis, and exhibits neuroprotective efficacy .

Ac-DNLD-CHO Ac-Asp-Asn-Leu-Asp-CHO	Caspase	Infection Neurological Disease
Ac-DNLD-CHO (Ac-Asp-Asn-Leu-Asp-CHO) is a Caspase-3/7 inhibitor (IC₅₀: 9.89, 245 nM respectively; K_i ^app: 0.68, 55.7 nM respectively). Ac-DNLD-CHO can be used for research of caspase-mediated apoptosis diseases, such as neurodegenerative disorders and viral infection diseases .

*Ac-AAVALLPAVLLALLAPVAD-CHO* TFA**	Caspase	Others
Ac-AAVALLPAVLLALLAPVAD-CHO (TFA) is a composite of Ac-VAD-CHO. Ac-AAVALLPAVLLALLAPVAD-CHO (TFA) is a non-selective caspase inhibitor as well as a cell permeable hydrophobic sequence derived from K-FGF .

Ac-ESMD-CHO	Casein Kinase	Others
Ac-ESMD-CHO is an inhibitor of caspase-3 and caspase-7. Ac-ESMD-CHO inhibits proteolytic cleavage of the caspase-3 precursor peptide (CPP32) at the Glu-Ser-Met-Asp (ESMD) site .

Ac-VDVAD-CHO	Caspase	Others
Ac-VDVAD-CHO is a caspase-2/3 inhibitor (IC₅₀: 46 and 15 nM) .

Z-Gly-Pro-Phe-Leu-CHO Z-GPFL-CHO	Proteasome	Cancer
Z-Gly-Pro-Phe-Leu-CHO (Z-GPFL-CHO) is a tetrapeptide aldehyde that acts as a highly selective and potent proteasomal inhibitor (K_i = 1.5 µM for branched chain amino acid preferring, 2.3 µM for small neutral amino acid preferring, and 40.5 µM for chymotrypsin-like activities; IC₅₀ = 3.1 µM for peptidyl-glutamyl peptide hydrolyzing activity) .

Ac-AAVALLPAVLLALLAP-LEHD-CHO	Caspase	Cancer
Ac-AAVALLPAVLLALLAP-LEHD-CHO is an inhibitor of caspases 4, 5 and 9. Ac-AAVALLPAVLLALLAP-LEHD-CHO shows protective effects upon Neocarzinostatin (HY-111183)-treated MCF-7 cells .

Boc-AEVD-CHO	Caspase Apoptosis	Inflammation/Immunology
Boc-AEVD-CHO is a Caspase 8 inhibitor useful in the study of apoptosis and immune and inflammatory diseases .

*Ac-LEVD-CHO* TFA**	Caspase Apoptosis	Cancer
Ac-LEVD-CHO (TFA) is an inhibitor of caspase-4. Ac-LEVD-CHO (TFA) can inhibit the expression and secretion of IL-1α expression as well as the activation of caspase-4 induced by the T. denticola periodontal pathogen surface protein Td92 in human gingival fibroblasts. Ac-LEVD-CHO (TFA) can also reduce the apoptosis due to the expression of the dominant negative adenoviral RNA-dependent protein kinase in A549 and PC3 cancer cell lines .

*Ac-VDVAD-CHO* TFA**	Caspase	Others
Ac-VDVAD-CHO (TFA) is a caspase-2/3 inhibitor (IC₅₀: 46 and 15 nM) .

Ac-AAVALLPAVLLALLAP-LEVD-CHO	Caspase	Cancer
Ac-AAVALLPAVLLALLAP-LEVD-CHO is a cell-permeable caspase-4 inhibitor that has antitumor activity .

Ac-AAVALLPAVLLALLAP-YVAD-CHO	Caspase	Cancer
Ac-AAVALLPAVLLALLAP-YVAD-CHO is a cell-permeable caspase-1 inhibitor that has antitumor activity .

**CHO-C-PEG2-C-CHO**	PROTAC Linkers	Cancer
CHO-C-PEG2-C-CHO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

Acid-PEG12-CHO	PROTAC Linkers	Cancer
Acid-PEG12-CHO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

Mal-PEG12-CHO	PROTAC Linkers	Cancer
Mal-PEG12-CHO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

Cat. No.	Product Name	Type

HY-D0257

Tartrazine 1 Publications Verification Acid Yellow 23; FD&C Yellow No. 5	Fluorescent Dyes
Tartrazine (Acid Yellow 23; FD&C Yellow No. 5) is an orally active azo acid dye, orange-yellow powder, soluble in water and turns yellow. Tartrazine is mainly used as a synthetic lemon yellow azo dye for food coloring. Tartrazine is the most stable colorant.Tartrazine induces mitochondria-mediated Apoptosis. Tartrazine can cause neurodevelopmental toxicity, cytotoxicity, and genotoxicity .

HY-18964G

MG-101

Calpain inhibitor I; Ac-LLnL-CHO; ALLN

Fluorescent Dyes

MG-101 (GMP) (Calpain inhibitor I (GMP)) is MG-101 (HY-18964) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. MG-101 (ALLN) is an inhibitor of cysteine proteases which inhibits calpain I, calpain II, cathepsin B and cathepsin L with K_is of 190, 220, 150 and 500 pM, respectively. MG-101 induces apoptosis and inhibits tumor growth, it can be used for the research of colon cancer .

HY-D3328

APC-Cy5.5	Fluorescent Dyes
APC-Cy5.5 is a tandem dye widely used in flow cytometry. It consists of the energy donor allophycocyanin (APC) and the energy acceptor Cy5.5, and operates via the fluorescence resonance energy transfer mechanism (Ex/Em = 650 nm/690 nm) .

Cat. No.	Product Name	Type

HY-76440

3-Oxetanone

Oxetan-3-one

Biochemical Assay Reagents

3-Oxetanone (Oxetan-3-one) is a four-membered cyclic ketone and strained cyclic ether derivative with measurable molecular g-value, magnetic susceptibility anisotropy and molecular quadrupole moment. 3-Oxetanone acts not only as a hydrogen bond acceptor, a tetrel donor and a weak hydrogen bond acceptor, but also forms a classic O-H···O hydrogen bond with H₂O via the ether oxygen atom. Alternatively, it forms a C···O tetrel bond with formaldehyde using its carbonyl group as a tetrel donor, while acting as a proton acceptor to form a C-H···O weak hydrogen bond with formaldehyde. 3-Oxetanone can be used to prepare various oxetanes .

HY-112624K

Dextran T5 (MW 5,000)

Dextran 5; Dextran D5; Dextran T5(MW 4500-5500)

Biochemical Assay Reagents

Dextran T5 (MW 5,000) is a sulfated polysaccharide anti-apoptotic and autophagic agent. Dextran T5 (MW 5,000) has sulfated groups and interacts with cell membranes by mimicking endogenous glycosaminoglycans, inhibiting the mitochondrial apoptotic pathway and delaying DNA fragmentation to exert anti-apoptotic activity. Dextran T5 (MW 5,000) also promotes the conversion of LC3-I to LC3-II and the formation of autophagosomes to activate the autophagic pathway. Dextran T5 (MW 5,000) can prolong the survival cycle of CHO cells and increase the production of recombinant erythropoietin (EPO). The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong drug half-life, increase local concentration and reduce immune clearance activity. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance .

HY-176509A

DSPE-PEG2000-CHO

Biochemical Assay Reagents

DSPE-PEG2000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG2000-CHO can be used for drug delivery .

HY-176509C

DSPE-PEG5000-CHO

Biochemical Assay Reagents

DSPE-PEG5000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG5000-CHO can be used for drug delivery .

HY-176509

DSPE-PEG1000-CHO

Biochemical Assay Reagents

DSPE-PEG1000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG1000-CHO can be used for drug delivery .

HY-155921

mPEG5000-CHO

mPEG5000-Aldehyde

Biochemical Assay Reagents

mPEG5000-CHO participates in the formation of a three-dimensional porous scaffold which carries active substances to form a delivery vehicle. The -CHO functional group interacts with the -NH2 functional group of the chitosan chain to form a glutaraldehyde-type adduct to functionalize mPEG. This functionalization and cross-linking can affect the rigidity of the delivery system, allowing slow release of the cross-linked conjugate system.

HY-18964G

MG-101

Calpain inhibitor I; Ac-LLnL-CHO; ALLN

Biochemical Assay Reagents

HY-158709

Cho-es-Lys	Biochemical Assay Reagents
Cho-es-Lys is a cationic lipid synthesized by coupling natural cholesterol and amino acids, which has high gene transfection efficiency. Cho-es-Lys can be used in drug delivery research .

HY-176509D

DSPE-PEG10000-CHO

Biochemical Assay Reagents

DSPE-PEG10000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG10000-CHO can be used for drug delivery .

HY-176509B

DSPE-PEG3400-CHO

Biochemical Assay Reagents

DSPE-PEG3400-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG3400-CHO can be used for drug delivery .

HY-176509H

DSPE-PEG40000-CHO

Biochemical Assay Reagents

DSPE-PEG40000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG40000-CHO can be used for drug delivery .

HY-155922

mPEG10000-CHO

mPEG10000-Aldehyde

Biochemical Assay Reagents

mPEG10000-CHO participates in the formation of a three-dimensional porous scaffold which carries active substances to form a delivery vehicle. The -CHO functional group interacts with the -NH2 functional group of the chitosan chain to form a glutaraldehyde-type adduct to functionalize mPEG. This functionalization and cross-linking can affect the rigidity of the delivery system, allowing slow release of the cross-linked conjugate system.

HY-155919

mPEG2000-CHO

mPEG2000-Aldehyde

Biochemical Assay Reagents

mPEG2000-CHO participates in the formation of a three-dimensional porous scaffold which carries active substances to form a delivery vehicle. The -CHO functional group interacts with the -NH2 functional group of the chitosan chain to form a glutaraldehyde-type adduct to functionalize mPEG. This functionalization and cross-linking can affect the rigidity of the delivery system, allowing slow release of the cross-linked conjugate system.

HY-155918

mPEG1000-CHO

mPEG1000-Aldehyde

Biochemical Assay Reagents

mPEG1000-CHO participates in the formation of a three-dimensional porous scaffold that carries active substances to form a delivery vehicle. The -CHO functional group interacts with the -NH2 functional group of the chitosan chain to form a glutaraldehyde-type adduct to functionalize mPEG. This functionalization and cross-linking can affect the rigidity of the delivery system, allowing slow release of the cross-linked conjugate system.

HY-174948

NHS-PEG1000-CHO NHS-PEG1000-Aldehyde	Biochemical Assay Reagents
NHS-PEG1000-CHO (NHS-PEG1000-Aldehyde) is a PEG derivative consisting of an aldehyde group (-CHO), a PEG unit, and an NHS ester. NHS esters can be conjugated to amino acids or other molecules containing amino groups. Aldehyde groups are reactive functional groups that can react with compounds containing amino or hydroxyl groups .

HY-174948C

NHS-PEG5000-CHO NHS-PEG5000-Aldehyde	Biochemical Assay Reagents
NHS-PEG5000-CHO (NHS-PEG5000-Aldehyde) is a PEG derivative consisting of an aldehyde group (-CHO), a PEG unit, and an NHS ester. NHS esters can be conjugated to amino acids or other molecules containing amino groups. Aldehyde groups are reactive functional groups that can react with compounds containing amino or hydroxyl groups .

HY-N0169A

Hyodeoxycholic acid sodium HDCA sodium	Biochemical Assay Reagents
Hyodeoxycholic acid sodium is a secondary bile acid formed in the small intestine by the gut flora, and acts as a TGR5 (GPCR19) agonist, with an EC₅₀ of 31.6 µM in CHO cells .

HY-123445

AZD7009	Biochemical Assay Reagents
AZD7009 is a novel antiarrhythmic agrnt. AZD7009 inhibits hKv1.5 and hKv4.3/hKChIP2.2 currents with IC₅₀s of 27.0 and 23.7 muM, respectively .

HY-183171

DSG-PEG1000-CHO	Biochemical Assay Reagents
DSG-PEG1000-CHO is a conjugate composed of DSG, a PEG chain, and a terminal aldehyde group (-CHO). DSG-PEG1000-CHO combines the membrane compatibility of phospholipids with the flexibility of hydroxyl modification, making it suitable for research in biomaterial construction and drug delivery.

HY-183171D

DSG-PEG10000-CHO	Biochemical Assay Reagents
DSG-PEG10000-CHO is a conjugate composed of DSG, a PEG chain, and a terminal aldehyde group (-CHO). DSG-PEG10000-CHO combines the membrane compatibility of phospholipids with the flexibility of hydroxyl modification, making it suitable for research in biomaterial construction and drug delivery.

HY-183171B

DSG-PEG5000-CHO	Biochemical Assay Reagents
DSG-PEG5000-CHO is a conjugate composed of DSG, a PEG chain, and a terminal aldehyde group (-CHO). DSG-PEG5000-CHO combines the membrane compatibility of phospholipids with the flexibility of hydroxyl modification, making it suitable for research in biomaterial construction and drug delivery.

HY-183171C

DSG-PEG3400-CHO	Biochemical Assay Reagents
DSG-PEG3400-CHO is a conjugate composed of DSG, a PEG chain, and a terminal aldehyde group (-CHO). DSG-PEG3400-CHO combines the membrane compatibility of phospholipids with the flexibility of hydroxyl modification, making it suitable for research in biomaterial construction and drug delivery.

HY-183171A

DSG-PEG2000-CHO	Biochemical Assay Reagents
DSG-PEG2000-CHO is a conjugate composed of DSG, a PEG chain, and a terminal aldehyde group (-CHO). DSG-PEG2000-CHO combines the membrane compatibility of phospholipids with the flexibility of hydroxyl modification, making it suitable for research in biomaterial construction and drug delivery.

HY-183398B

DMG-PEG3400-CHO	Biochemical Assay Reagents
DMG-PEG3400-CHO is a conjugate composed of dimyristic glycerol (DMG), a PEG chain, and a terminal aldehyde group (-CHO). DMG-PEG3400-CHO combines the membrane compatibility of phospholipids with the flexibility of hydroxyl modification, making it suitable for research in biomaterial construction and drug delivery.

HY-183398A

DMG-PEG2000-CHO	Biochemical Assay Reagents
DMG-PEG2000-CHO is a conjugate composed of dimyristic glycerol (DMG), a PEG chain, and a terminal aldehyde group (-CHO). DMG-PEG2000-CHO combines the membrane compatibility of phospholipids with the flexibility of hydroxyl modification, making it suitable for research in biomaterial construction and drug delivery.

HY-183398D

DMG-PEG10000-CHO	Biochemical Assay Reagents
DMG-PEG10000-CHO is a conjugate composed of dimyristic glycerol (DMG), a PEG chain, and a terminal aldehyde group (-CHO). DMG-PEG10000-CHO combines the membrane compatibility of phospholipids with the flexibility of hydroxyl modification, making it suitable for research in biomaterial construction and drug delivery.

HY-183398C

DMG-PEG5000-CHO	Biochemical Assay Reagents
DMG-PEG5000-CHO is a conjugate composed of dimyristic glycerol (DMG), a PEG chain, and a terminal aldehyde group (-CHO). DMG-PEG5000-CHO combines the membrane compatibility of phospholipids with the flexibility of hydroxyl modification, making it suitable for research in biomaterial construction and drug delivery.

HY-183398

DMG-PEG1000-CHO	Biochemical Assay Reagents
DMG-PEG1000-CHO is a conjugate composed of dimyristic glycerol (DMG), a PEG chain, and a terminal aldehyde group (-CHO). DMG-PEG1000-CHO combines the membrane compatibility of phospholipids with the flexibility of hydroxyl modification, making it suitable for research in biomaterial construction and drug delivery.

HY-176509E

DSPE-PEG20000-CHO

Biochemical Assay Reagents

DSPE-PEG20000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG20000-CHO can be used for drug delivery .

HY-W1048508B

2-Arm PEG40000-CHO	Biochemical Assay Reagents
2-Arm PEG40000-CHO is a multi-arm PEG derivative that can be used for drug delivery .

HY-W1048508A

2-Arm PEG20000-CHO	Biochemical Assay Reagents
2-Arm PEG20000-CHO is a multi-arm PEG derivative that can be used for drug delivery .

HY-W1048508D

2-Arm PEG10000-CHO	Biochemical Assay Reagents
2-Arm PEG10000-CHO is a multi-arm PEG derivative that can be used for drug delivery .

HY-W1123946H

8-Arm-PEG10000-CHO	Biochemical Assay Reagents
8-Arm-PEG10000-CHO is a polyethylene glycol derivative with multiple active aldehyde groups, which can be used to construct drug delivery carriers .

HY-W1123946A

8-Arm-PEG40000-CHO	Biochemical Assay Reagents
8-Arm-PEG40000-CHO is a polyethylene glycol derivative with multiple active aldehyde groups, which can be used to construct drug delivery carriers .

HY-W1123946

8-Arm-PEG20000-CHO	Biochemical Assay Reagents
8-Arm-PEG20000-CHO is a polyethylene glycol derivative with multiple active aldehyde groups, which can be used to construct drug delivery carriers .

HY-W1123937A

Biotin-PEG2000-CHO	Biochemical Assay Reagents
Biotin-PEG2000-CHO is a biotin-conjugated PEG derivative that can be used to biotinylate biomolecules or other surfaces. Biotin can be easily detected by biotin/streptavidin binding assay and is widely used in molecular targeted detection .

HY-W1123937B

Biotin-PEG3400-CHO	Biochemical Assay Reagents
Biotin-PEG3400-CHO is a biotin-conjugated PEG derivative that can be used to biotinylate biomolecules or other surfaces. Biotin can be easily detected by biotin/streptavidin binding assay and is widely used in molecular targeted detection .

HY-W1123937

Biotin-PEG1000-CHO	Biochemical Assay Reagents
Biotin-PEG1000-CHO is a biotin-conjugated PEG derivative that can be used to biotinylate biomolecules or other surfaces. Biotin can be easily detected by biotin/streptavidin binding assay and is widely used in molecular targeted detection .

HY-155923

mPEG20000-CHO

mPEG20000-Aldehyde

Biochemical Assay Reagents

mPEG20000-CHO participates in the formation of a three-dimensional porous scaffold which carries active substances to form a delivery vehicle. The -CHO functional group interacts with the -NH2 functional group of the chitosan chain to form a glutaraldehyde-type adduct to functionalize mPEG. This functionalization and cross-linking can affect the rigidity of the delivery system, allowing slow release of the cross-linked conjugate system.

HY-174948B

NHS-PEG3400-CHO NHS-PEG3400-Aldehyde	Biochemical Assay Reagents
NHS-PEG3400-CHO (NHS-PEG3400-Aldehyde) is a PEG derivative consisting of an aldehyde group (-CHO), a PEG unit, and an NHS ester. NHS esters can be conjugated to amino acids or other molecules containing amino groups. Aldehyde groups are reactive functional groups that can react with compounds containing amino or hydroxyl groups .

HY-174948A

NHS-PEG2000-CHO NHS-PEG2000-Aldehyde	Biochemical Assay Reagents
NHS-PEG2000-CHO (NHS-PEG2000-Aldehyde) is a PEG derivative consisting of an aldehyde group (-CHO), a PEG unit, and an NHS ester. NHS esters can be conjugated to amino acids or other molecules containing amino groups. Aldehyde groups are reactive functional groups that can react with compounds containing amino or hydroxyl groups .

HY-W1048508C

*2-Arm PEG-CHO* (MW 5000)**	Biochemical Assay Reagents
2-Arm PEG-CHO (MW 5000) is a multi-arm PEG derivative that can be used for drug delivery .

HY-W1123937C

Biotin-PEG5000-CHO	Biochemical Assay Reagents
Biotin-PEG-CHO (with a molecular weight of 5000) is a biotin-attached PEG derivative that can be used for biotinylation of biological molecules or other material surfaces. Biotin can be easily detected through the biotin/streptavidin binding test, and is widely used in molecular targeted detection.

Cat. No.	Product Name	Target	Research Area

HY-P4146

Survodutide BI 456906	GLP Receptor GCGR	Metabolic Disease
Survodutide (BI 456906) is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC₅₀s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively. Survodutide, a 29-amino-acid peptide, is a potent acylated peptide containing a C18 fatty acid. Survodutide has robust anti-obesity efficacy achieved by increasing energy expenditure and decreasing food intake .

HY-P1001

Ac-DEVD-CHO Maximum Cited Publications 46 Publications Verification	Caspase	Cancer
Ac-DEVD-CHO is a Caspase-3 inhibitor with a K_i value of 230 pM.

HY-P2542

GIP (3-42), human	Insulin Receptor	Metabolic Disease
GIP (3-42), human acts as a glucose-dependent insulinotropic polypeptide (GIP) receptor antagonist, moderating the insulin secreting and metabolic actions of GIP in vivo .

HY-P10149

Ac-IEPD-CHO 1 Publications Verification	Caspase	Cancer
Ac-IEPD-CHO is a reversible granzyme B inhibitor with a K_i of 80 nM . Ac-IEPD-CHO is also a caspase-8 inhibitor .

HY-120019

Ac-YVAD-CHO L-709049	Interleukin Related Apoptosis Caspase	Inflammation/Immunology
Ac-YVAD-CHO (L-709049) is a potent, reversible, specific tetrapeptide interleukin-lβ converting enzyme (ICE) inhibitor with mouse and human K_i values of 3.0 and 0.76 nM. Ac-YVAD-CHO is also a caspase-1 inhibitor. Ac-YVAD-CHO can suppress the production of mature IL-lβ .

HY-108003

MM 07	Apelin Receptor (APJ)	Cardiovascular Disease
MM 07 is a biased apelin receptor agonist, with a K_D of 300 nM in CHO-K1 cells and a K_D of 172 nM in human heart.

HY-P1205A

MCH(human, mouse, rat) TFA 1 Publications Verification Melanin-concentrating hormone(human, mouse, rat) TFA	MCHR1 (GPR24)	Neurological Disease Metabolic Disease
MCH (human, mouse, rat) TFA is a cyclic neuropeptide mainly synthesized by neurons in the lateral hypothalamic area. MCH (human, mouse, rat) TFA also serves as an endogenous ligand for the melanin-concentrating hormone receptor (MHC receptor), with a binding IC₅₀ of 0.3 nM and 1.5 nM for human MCH-1R and MCH-2R, respectively; its functional EC₅₀ values are 3.9 nM and 88.7 nM. MCH (human, mouse, rat) TFA acts not only as an orexigenic signal but also as a key integrating and regulatory hormone for energy homeostasis and sleep-wake cycles. MCH (human, mouse, rat) TFA can be used in studies related to obesity, sleep disorders, and other associated conditions .

HY-P1526

ANP [Des18-22] 4-23 amide (rat)	Natriuretic Peptide Receptor (NPR)	Cardiovascular Disease
ANP [Des18-22] 4-23 amide rat is a polypeptide fragment of rat atrial natriuretic peptide (ANP) that specifically binds NPR-C .

HY-P1366

des-Gln14-Ghrelin 1 Publications Verification	GHSR	Metabolic Disease
des-Gln14-Ghrelin is a second endogenous ligand for the growth hormone secretagogue receptor. a). des-Gln14-ghrelin potently induces increases in [Ca ²⁺]i in CHO-GHSR62 cells, with an EC₅₀ of 2.4 nM .

HY-136727

Ac-LEVD-CHO 1 Publications Verification	Caspase	Cancer
Ac-LEVD-CHO is a caspase-4 inhibitor. Ac-LEVD-CHO is a peptide with the sequence of Ac-Leu-Glu-Val-Asp-al .

HY-113963

Ac-IETD-CHO	Apoptosis	Cancer
Ac- IETD- CHO is a potent, reversible inhibitor of granzyme B and caspase-8. Ac- IETD- CHO inhibits Fas-mediated apoptotic cell death, hemorrhage, and liver failure. Ac- IETD- CHO also inhibits cytotoxic T lymphocytes induced cell death .

HY-120234

Z-LLNle-CHO Z-Leu-Leu-Nle-CHO; GSII	γ-secretase Proteasome Apoptosis	Cancer
Z-LLNle-CHO (Z-Leu-Leu-Nle-CHO) is a γ-secretase inhibitor I. Z-LLNle-CHO induces caspase and ROS-dependent apoptosis by blocking the Akt-mediated pro-survival pathway. Z-LLNle-CHO can be used in cancer research, such as breast cancer and leukaemia .

HY-108312A

*Ac-VEID-CHO* TFA**	Caspase	Neurological Disease
Ac-VEID-CHO (TFA) is a peptide-derived caspase inhibitor and has potency of inhibition for Caspase-6, Caspase-3 and Caspase-7 with IC₅₀ values of 16.2 nM, 13.6 nM and 162.1 nM, respectively. Ac-VEID-CHO (TFA) can be used for the research of neurodegenerative conditions including Alzheimer’s and Huntington’s disease .

HY-P4990

Pro8-Oxytocin	Oxytocin Receptor	Endocrinology
Pro8-Oxytocin is a a modified oxytocin (OXT) ligand. Pro8-Oxytocin produces more potent and efficacious responses at primate OXTR and stronger behavioral effects than the consensus mammalian OXT ligand (Leu8-Oxytocin). Pro8-Oxytocin produce a less efficacious response than Vasopressin (HY-B1811) (AVP) at human AVPR1a and higher efficacious response than AVP at marmoset AVPR1a .

HY-P1217

[D-Trp8]-γ-MSH	Melanocortin Receptor	Inflammation/Immunology
[D-Trp8]-γ-MSH is a potent and selective agonist of melanocortin 3 (MC3) receptor, with IC₅₀s of 6.7 nM, 600 nM and 340 nM for hMC3, hMC4 and hMC5, respectively in CHO cells. [D-Trp8]-γ-MSH could provide protection against multiple inflammatory disorders such as rheumatoid arthritis and colitis .

HY-134454

Z-Pro-Pro-CHO	Prolyl Endopeptidase (PREP) Parasite	Infection
Z-Pro-Pro-CHO is a potent inhibitor of prolyl oligopeptidase (POP), with extremely high affinity for human prolyl oligopeptidase (HsPOP) (IC₅₀=0.012 μM), and it also effectively inhibits the activity of Schistosoma mansoni prolyl oligopeptidase (SmPOP) (IC₅₀=0.16 μM). Z-Pro-Pro-CHO does not block the phosphorylation of ERK or the production of TNF-α or IFN-γ in immune cells from presensitized mice, nor does it induce harmful phenotypes in cultured Schistosoma mansoni schistosomula. Z-Pro-Pro-CHO only partially inhibits epithelial cell wound healing at extremely high concentrations. Z-Pro-Pro-CHO finds wide application in studies related to schistosomiasis .

HY-P4349A

Pyr-Arg-Thr-Lys-Arg-AMC TFA	Biochemical Assay Reagents Thrombin	Others
Pyr-Arg-Thr-Lys-Arg-AMC TFA is a AMC peptide, and a fluorescent substrate. Pyr-Arg-Thr-Lys-Arg-AMC TFA can be used to detect the activity of specific proteases, such as Furin, Trypsin, and Thrombin .

HY-137392

Cathepsin L-IN-4 1-Naphthalenesulfonyl-Ile-Trp-CHO	Cathepsin	Others
Cathepsin L-IN-4 is an inhibitor of cathepsin L with IC₅₀ at nanomolar concentrations .

HY-P4222

IETD-CHO Caspase-8-IN-1	Caspase	Others
IETD-CHO (Caspase-8-IN-1) is a potent caspase-8 inhibitor .

HY-P2000

Septide (Pyr6,Pro9)-Substance P	Neurokinin Receptor	Neurological Disease
Septide ((Pyr6,Pro9)-Substance P) is a potent NK1 receptor agonist with a K_d value of 0.55 nM .

HY-P1258

PSI 2 Publications Verification Proteasome Inhibitor 1; Z-Ile-Glu(OtBu)-Ala-Leu-CHO	Proteasome	Infection Cancer
PSI (Proteasome Inhibitor 1) is a potent proteasome inhibitor. PSI inhibits the proliferation of primary effusion lymphoma (PEL) cells. PSI has the potential for the research of Kaposi’s sarcoma-associated herpesvirus (KSHV) infection and KSHV-associated lymphomas .

HY-P10038A

mP6 TFA Myr-FEEERA-OH TFA	Integrin	Infection
mP6 (Myr-FEEERA-OH) TFA is a myristoylated peptide. mP6 TFA inhibits the interaction of Gα13 with integrin β3 without disrupting talin-dependent integrin function. mP6 TFA can block the GTP usage of Rac1, Rap1, and Rab7, effectively inhibiting the infection of CHO-A24 cells .

HY-P10241

Ac-LEHD-CHO	Apoptosis Caspase	Cancer
Ac-LEHD-CHO is an inhibitor for caspase 8/9. Ac-LEHD-CHO prevents GalN/TNF-α-induced hepatotoxicity and hepatocyte apoptosis .

HY-P5830A

*Biotin-DEVD-CHO* TFA**	Caspase Orexin Receptor (OX Receptor)	Others
Biotin-DEVD-CHO (TFA) is a biotin-conjugated form of the caspase-3 and -7 inhibitor – Ac-DEVD-CHO. Biotin-DEVD-CHO (TFA) can be used for affinity purification of the active caspase-3, -6, -7, and -8. Biotin-DEVD-CHO (TFA) can detect the active caspase-3 in vitro .

HY-P5890A

*YVAD-CHO* TFA**	Caspase Interleukin Related	Neurological Disease Inflammation/Immunology
YVAD-CHO TFA is an interleukin-1β converting enzyme (ICE, caspase 1) inhibitor (K_i: 0.76 nM). YVAD-CHO TFA inhibits mature IL-1β production. YVAD-CHO TFA partially delays motoneurone death in lesioned facial nerve mice .

HY-P4146A

Survodutide TFA BI 456906 TFA	GLP Receptor GCGR	Metabolic Disease
Survodutide (BI 456906) TFA is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC₅₀s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively. Survodutide TFA, a 29-amino-acid peptide, is a potent acylated peptide containing a C18 fatty acid. Survodutide TFA has robust anti-obesity efficacy achieved by increasing energy expenditure and decreasing food intake .

HY-P5830

Biotin-DEVD-CHO	Caspase	Others
Biotin-DEVD-CHO can be used for affinity labeling of Caspase-8 following in vitro caspase cleavage .

HY-P1320

[Nphe1]Nociceptin(1-13)NH2	Opioid Receptor	Inflammation/Immunology
[Nphe1]Nociceptin(1-13)NH2, a novel nociceptin/orphanin FQ (NC) endogenous ligand, is a selective and competitive ociceptin receptor antagonist without any residual agonist activity. [Nphe1]nociceptin(1-13)NH2 binds selectively to recombinant nociceptin receptors (pK_i=8.4) and antagonizes the inhibitory effects of nociceptin on cyclic AMP accumulation in CHO cells (pA₂=6.0). [Nphe1]Nociceptin(1-13)NH2 has the potential to act as an analgesic agent .

HY-P5890

YVAD-CHO	Interleukin Related Caspase	Neurological Disease Inflammation/Immunology
YVAD-CHO is an interleukin-1β converting enzyme (ICE, caspase 1) inhibitor (K_i: 0.76 nM). YVAD-CHO inhibits mature IL-1β production. YVAD-CHO partially delays motoneurone death in lesioned facial nerve mice .

HY-W011254

Ac-VAD-CHO Ac-Val-Ala-Asp-CHO	Caspase	Cancer
Ac-VAD-CHO (Ac-Val-Ala-Asp-CHO) is a pan-caspase inhibitor. Ac-VAD-CHO inhibits dissipation of MMP and cytochrome c release in hypoxia-exposed cells .

HY-P3176

Motilin, human, porcine	Motilin Receptor	Others
Motilin, human, porcine is a gastrointestinal hormone, which is released during fasting and after eating, or by drinking water. Motilin, human, porcine promotes enteric cholinergic activity in human stomach with an EC₅₀ of 33 nM, and thus modulates gastrointestinal motility function .

HY-P5936

Ac-AAVALLPAVLLALLAP-DEVD-CHO DEVD-CHO-CPP 32	Caspase	Cancer
Ac-AAVALLPAVLLALLAP-DEVD-CHO (DEVD-CHO-CPP 32) is a potent and reversible caspase-3 inhibitor .

HY-138096

Z-LLF-CHO Z-Leu-Leu-Phe-CHO	Proteasome	Cancer
Z-LLF-CHO (Z-Leu-Leu-Phe-CHO) is a potent inhibitor of the chymotrypsin-like activity of the pituitary multicatalytic proteinase complex (K_i = 460 nM). Z-LLF-CHO is also a NF-κB nuclear translocation inhibitor .

HY-P10146

Ac-LETD-CHO	Caspase	Cancer
Ac-LETD-CHO is a caspases 8 inhibitor. Ac-LETD-CHO has specific inhibition to casp-8 with an IC₅₀ value of 6.71 nM. Ac-LETD-CHO can be used for the research of anticancer .

HY-P2374

Ac-DMQD-CHO	Caspase Apoptosis	Neurological Disease
Ac-DMQD-CHO is a selective inhibitor for caspase 3, with IC₅₀ of 39 nM. Ac-DMQD-CHO reduces apoptosis, and exhibits neuroprotective efficacy .

HY-136733

Ac-DNLD-CHO Ac-Asp-Asn-Leu-Asp-CHO	Caspase	Infection Neurological Disease
Ac-DNLD-CHO (Ac-Asp-Asn-Leu-Asp-CHO) is a Caspase-3/7 inhibitor (IC₅₀: 9.89, 245 nM respectively; K_i ^app: 0.68, 55.7 nM respectively). Ac-DNLD-CHO can be used for research of caspase-mediated apoptosis diseases, such as neurodegenerative disorders and viral infection diseases .

HY-P10955

*Ac-AAVALLPAVLLALLAPVAD-CHO* TFA**	Caspase	Others
Ac-AAVALLPAVLLALLAPVAD-CHO (TFA) is a composite of Ac-VAD-CHO. Ac-AAVALLPAVLLALLAPVAD-CHO (TFA) is a non-selective caspase inhibitor as well as a cell permeable hydrophobic sequence derived from K-FGF .

HY-P3234

Ac-ESMD-CHO	Casein Kinase	Others
Ac-ESMD-CHO is an inhibitor of caspase-3 and caspase-7. Ac-ESMD-CHO inhibits proteolytic cleavage of the caspase-3 precursor peptide (CPP32) at the Glu-Ser-Met-Asp (ESMD) site .

HY-P1542

Urotensin I Catostomus urotensin I	CRFR	Cardiovascular Disease Endocrinology
Urotensin I (Catostomus urotensin I), a CRF-like neuropeptide, acts as an agonist of CRF receptor with pEC₅₀s of 11.46, 9.36 and 9.85 for human CRF₁, human CRF₂ and rat CRF_2α receptors in CHO cells, and K_is of 0.4, 1.8, and 5.7 nM for hCRF₁, rCRF_2α and mCRF_2β receptors, respectively .

HY-P1542B

Urotensin I TFA Catostomus urotensin I TFA	CRFR	Cardiovascular Disease Endocrinology
Urotensin I (Catostomus urotensin I) TFA, a CRF-like neuropeptide, acts as an agonist of CRF receptor with pEC₅₀s of 11.46, 9.36 and 9.85 for human CRF₁, human CRF₂ and rat CRF_2α receptors in CHO cells, and K_is of 0.4, 1.8, and 5.7 nM for hCRF₁, rCRF_2α and mCRF_2β receptors, respectively .

HY-P4146B

Survodutide sodium BI 456906 sodium	GLP Receptor GCGR	Metabolic Disease
Survodutide (BI 456906) sodium is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC₅₀s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively. Survodutide sodium, a 29-amino-acid peptide, is a potent acylated peptide containing a C18 fatty acid. Survodutide sodium has robust anti-obesity efficacy achieved by increasing energy expenditure and decreasing food intake .

HY-134567

Ac-VDVAD-CHO	Caspase	Others
Ac-VDVAD-CHO is a caspase-2/3 inhibitor (IC₅₀: 46 and 15 nM) .

HY-P5757

(D-Trp32)-Neuropeptide Y (porcine) (D-Trp32)-NPY	Neuropeptide Y Receptor	Neurological Disease
(D-Trp32)-Neuropeptide Y (porcine) is a highly selective neuropeptide Y (NPY) Y5 receptor agonist. (D-Trp32)-Neuropeptide Y (porcine) has orexigenic activity and inhibits Forskolin (HY-15371)-stimulated cAMP formation .

HY-P10007

Z-Gly-Pro-Phe-Leu-CHO Z-GPFL-CHO	Proteasome	Cancer
Z-Gly-Pro-Phe-Leu-CHO (Z-GPFL-CHO) is a tetrapeptide aldehyde that acts as a highly selective and potent proteasomal inhibitor (K_i = 1.5 µM for branched chain amino acid preferring, 2.3 µM for small neutral amino acid preferring, and 40.5 µM for chymotrypsin-like activities; IC₅₀ = 3.1 µM for peptidyl-glutamyl peptide hydrolyzing activity) .

HY-P5956

Ac-AAVALLPAVLLALLAP-LEHD-CHO	Caspase	Cancer
Ac-AAVALLPAVLLALLAP-LEHD-CHO is an inhibitor of caspases 4, 5 and 9. Ac-AAVALLPAVLLALLAP-LEHD-CHO shows protective effects upon Neocarzinostatin (HY-111183)-treated MCF-7 cells .

HY-P5834

Boc-AEVD-CHO	Caspase Apoptosis	Inflammation/Immunology
Boc-AEVD-CHO is a Caspase 8 inhibitor useful in the study of apoptosis and immune and inflammatory diseases .

HY-136727A

*Ac-LEVD-CHO* TFA**	Caspase Apoptosis	Cancer
Ac-LEVD-CHO (TFA) is an inhibitor of caspase-4. Ac-LEVD-CHO (TFA) can inhibit the expression and secretion of IL-1α expression as well as the activation of caspase-4 induced by the T. denticola periodontal pathogen surface protein Td92 in human gingival fibroblasts. Ac-LEVD-CHO (TFA) can also reduce the apoptosis due to the expression of the dominant negative adenoviral RNA-dependent protein kinase in A549 and PC3 cancer cell lines .

HY-134567A

*Ac-VDVAD-CHO* TFA**	Caspase	Others
Ac-VDVAD-CHO (TFA) is a caspase-2/3 inhibitor (IC₅₀: 46 and 15 nM) .

HY-P5955

Ac-AAVALLPAVLLALLAP-LEVD-CHO	Caspase	Cancer
Ac-AAVALLPAVLLALLAP-LEVD-CHO is a cell-permeable caspase-4 inhibitor that has antitumor activity .

HY-P5938

Ac-AAVALLPAVLLALLAP-YVAD-CHO	Caspase	Cancer
Ac-AAVALLPAVLLALLAP-YVAD-CHO is a cell-permeable caspase-1 inhibitor that has antitumor activity .

Cat. No.	Product Name

HY-K0226

CHO Magnetic Beads (200 nm, 10 mg/mL)
MCE CHO Magnetic Beads (200 nm, 10 mg/mL) contain CHO functional groups, which react with primary amines on proteins or other molecules to form stable amide linkages，can covalently immobilize proteins for the affinity purification of antibodies, antigens and other biomolecules.

HY-K3030

Ham's F-12K (Kaighn's)

Ham’s F-12K Medium was originally designed for the culture of primary human hepatocytes and differentiated rat and chicken cells. It is particularly suitable for single-cell cloning of Chinese hamster ovary (CHO) cells under serum-free conditions. When supplemented with serum, it can also be used for the culture of various other mammalian cell types, including chondrocytes and rat prostate epithelial cells.

HY-K2014

PEI Transfection Reagent

50+ Cited Publications

MCE PEI Transfection Reagent is designed based on 25 kDa PEI. It has high-efficiency, low-toxicity, strong-stability, and is suitable for many cell types, such as HEK-293、HEK-293T、CHO-K1、COS-1、COS-7、NIH/3T3、Sf9、HepG2 and HeLa et, even some hard-to-transfect cells. It can also be applied to large-scale recombinant protein expression and virus production. The 1 mL is defined as the base specification. All larger sizes correspond to incremental volumes of this base.

Cat. No.	Product Name	Target	Research Area	Image

HY-P990008

Atrosab 1 Publications Verification	TNF Receptor Apoptosis	Inflammation/Immunology
Atrosab is a humanized IgG1 antagonistic anti-TNFR1 antibody. Atrosab inhibits TNF-mediated Apoptosis induction and IL-6 and IL-8 production. Atrosab reduces neurological deficits. Atrosab can be used for research of inflammatory disease. The recommend isotype control is Human IgG1 kappa, Isotype Control (HY-P99001) .

HY-P99369

Lacutamab IPH 4102; Anti-KIR3DL2/CD158k Reference Antibody (lacutamab)	Inhibitory Antibodies	Cancer
Lacutamab (IPH4102) is a humanizedized monoclonal antibody (mAb) directed against the immune receptor molecule KIR3DL2, produced by recombinant technology in CHO cells. Lacutamab can be used in research of cutaneous T-cell lymphoma .

HY-P990651

PY314	TREM receptor	Inflammation/Immunology
PY314 is a humanized antibody expressed in CHO, targeting TREM2. PY314 has a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for PY314 can refer to Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P990642

Oportuzumab	Transmembrane Glycoprotein	Inflammation/Immunology
Oportuzumab is a CHO-expressed humanized antibody that targets EpCAM/TROP1/CD326. Oportuzumab contains a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for Oportuzumab can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P99870

Eblasakimab ASLAN004; CSL-334; MK-6105	Interleukin Related	Others
Eblasakimab (ASLAN004; CSL-334) is a human IgG4 antibody that specifically targets IL13RA1 and is primarily expressed by CHO-K1 cells .

HY-P990009

Nisevokitug NIS-793	TGF-beta/Smad	Cancer
Nisevokitug (NIS-793) is a human, IgG2λ antibody targeting TGF-β (TGFB1/TGFB2). Nisevokitug is expressed by CHO-K1 cells .

HY-P991104

Anti-EMMPRIN/CD147 Antibody	Integrin	Metabolic Disease
Anti-EMMPRIN/CD147 Antibody is a human antibody expressed in CHO cells, targeting Basigin. Anti-EMMPRIN/CD147 Antibody can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P990501

Anti-RSPO1 Antibody	Wnt β-catenin	Inflammation/Immunology
Anti-RSPO1 Antibody is a humanized antibody expressed in CHO that targets RSPO1. The isotype control for Anti-RSPO1 Antibody can be referenced as Mouse IgG2a kappa, Isotype Control (HY-P99978).

HY-P990355

Anti-CD5 Antibody	Inhibitory Antibodies	Inflammation/Immunology
Anti-CD5 Antibody is a human-derived antibody expressed in CHO, targeting CD5. Anti-CD5 Antibody contains huIgG1 heavy chains and huκ light chains, with a predicted molecular weight (MW) of 145.05 kDa.

HY-P99610

Ezabenlimab BI-754091	PD-1/PD-L1	Cancer
Ezabenlimab (BI-754091) is an anti-PD-1 mAb with binding constant K_d value of 6 nM (CHO cells). Ezabenlimab blocks the interaction of PD-1 with PD-L1 and PD-L2. Ezabenlimab increases interferon-γ secretion in T cells, and inhibits tumor growth in vivo .

HY-P9980A

Belantamab (FUT8-KO)	ADC Antibody TNF Receptor	Cancer
Belantamab (FUT8-KO) is an anti-BCMA (TNFRSF17) monoclonal antibody expressed by CHO cells with the fucosyltransferase 8 gene (FUT8) knocked out. Fucose deficiency enhances the ADCC effect of the antibody. Belantamab (FUT8-KO) can be used to synthesize antibody-active molecule conjugate (ADC), Belantamab mafodotin .

HY-P990669

Torudokimab	Interleukin Related	Inflammation/Immunology
Torudokimab is a humanized antibody expressed in CHO, targeting IL-33. Torudokimab has a huIgG4SP type heavy chain and a huκ type light chain, with a predicted molecular weight (MW) of 145.22 kDa. The isotype control for Torudokimab can refer to Human IgG4 kappa, Isotype Control (HY-P99003).

HY-P990635

NGM-120	Inhibitory Antibodies	Inflammation/Immunology
NGM-120 is a CHO-expressed human antibody that targets GFRAL. NGM-120 contains huIgG1 heavy chain and huκ light chain, with a predicted molecular weight (MW) of 145.7 kDa. The isotype control for NGM-120 can refer to Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P99865

Dresbuxelimab AK-119	CD73	Others
Dresbuxelimab (AK-119) is an IgG-κ monoclonal antibody targeting CD73. The expression system is usually CHO (Chinese Hamster Ovary) cells .

HY-P99109

Zimberelimab GLS-010; AB-122; WBP-3055	PD-1/PD-L1	Cancer
Zimberelimab (GLS-010) is a fully human IgG4 anti-PD-1 monoclonal antibody with an EC₅₀ of 210 pM for human PD-1. Zimberelimab effectively blocks the binding of PD-L1 and PD-L2 to cell-surface PD-1 in CHO-S cells, with IC₅₀ values of 580 pM and 670 pM, respectively. Zimberelimab shows antitumor activities, and can be used for various cancers research, including cervical cancer, non-small cell lung cancer and classical Hodgkin’s lymphoma .

HY-P990607

Indatuximab	Transmembrane Glycoprotein	Inflammation/Immunology
Indatuximab is a CHO-expressed chimeric antibody that targets Syndecan-1/CD138. The predicted molecular weight (MW) of Indatuximab is 145.5 kDa. The isotype control for Indatuximab can refer to Human IgG4 kappa, Isotype Control (HY-P99003).

HY-P990571

Coltuximab 1 Publications Verification	CD19	Inflammation/Immunology
Coltuximab is a CHO-expressed humanized antibody that targets CD19. Coltuximab is composed of huIgG1 heavy chains and huκ light chains, with a molecular weight (MW) of 144.70 kDa. The isotype control for Coltuximab can refer to Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P990587

FR104 1 Publications Verification	CD28	Inflammation/Immunology
FR104 is a humanized antibody expressed in CHO cells that targets CD28. FR104 comprises a huIgG2 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for FR104 can be referenced as Human IgG2 kappa, Isotype Control (HY-P99002).

HY-P990569

CM-24 MK-6018	Inhibitory Antibodies	Inflammation/Immunology
CM-24 is a humanized antibody expressed in CHO cells, targeting CEACAM1/CD66a. The predicted molecular weight (MW) of CM-24 is 145 kDa. The isotype control for CM-24 can refer to Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P990631

Mibavademab	Neuropeptide Y Receptor	Inflammation/Immunology
Mibavademab is a CHO-expressed humanized antibody that targets LEPR/CD295. Mibavademab is equipped with a huIgG4SP heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 145.58 kDa. The isotype control for Mibavademab can be referenced as Human IgG4 kappa, Isotype Control (HY-P99003).

HY-P990496

Anti-PVRIG Antibody (COM701) COM701	Transmembrane Glycoprotein	Inflammation/Immunology
Anti-PVRIG Antibody (COM701) is a CHO-expressed human antibody that targets PVRIG. The predicted molecular weight (MW) of Anti-PVRIG Antibody (COM701) is 145.48 kDa. The isotype control for Anti-PVRIG Antibody (COM701) can be referenced as Human IgG4 kappa, Isotype Control (HY-P99003).

HY-P991108

Anti-CDH6/K-Cadherin Antibody HKT288 antibody	Transmembrane Glycoprotein	Cancer
Anti-CDH6/K-Cadherin Antibody (HKT288 antibody) is a human antibody expressed in CHO cells, targeting CDH6. Anti-CDH6/K-Cadherin Antibody (HKT288 antibody) can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P990480

Anti-oxLDL Antibody	LDLR	Inflammation/Immunology
The Anti-oxLDL Antibody is a humanized antibody expressed in CHO cells that targets oxLDL. The Anti-oxLDL Antibody has a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for the Anti-oxLDL Antibody can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P990636

NGM-313 MK-3655	Inhibitory Antibodies	Inflammation/Immunology
NGM-313 is a CHO-expressed human antibody targeting Klotho Beta. NGM-313 contains a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for NGM-313 can refer to Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P990322

AMG-811	Inhibitory Antibodies	Inflammation/Immunology
AMG-811 is a CHO expressed human antibody that targets IFNg. AMG-811 carries a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for AMG-811 can refer to Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P990675

VGX-100	VEGFR	Inflammation/Immunology
VGX-100 is a humanized antibody expressed in CHO cells, targeting VEGFC. VGX-100 is composed of huIgG1 heavy chains and huλ light chains, with a predicted molecular weight (MW) of 143.6 kDa. The isotype control for VGX-100 can refer to Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P99869

Ebdarokimab	Interleukin Related	Others
Ebdarokimab (AK101) is a humanized IgG1-κ antibody, usually expressed in CHO (Chinese Hamster Ovary) cells .

HY-P99888

Pimurutamab	EGFR	Others
Pimurutamab is a humanized IgG1-κ antibody targeting EGFR. Mainly expressed by CHO-K1 cells .

HY-P991103

Anti-IL-25 Antibody	Interleukin Related	Inflammation/Immunology
Anti-IL-25 Antibody is a human antibody expressed in CHO cells, targeting IL-25. Anti-IL-25 Antibody can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P991109

Anti-EFNA4 Antibody PF-06647263 antibody	Transmembrane Glycoprotein	Neurological Disease
Anti-EFNA4 Antibody (PF-06647263 antibody) is a human antibody expressed in CHO cells, targeting EFNA4. Anti-EFNA4 Antibody can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P991099

Anti-GLP1R Antibody	GCGR	Metabolic Disease
Anti-GLP1R Antibody is a human antibody expressed in CHO cells, targeting GLP1R. Anti-GLP1R Antibody can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P990554

BHQ-880	Inhibitory Antibodies	Inflammation/Immunology
BHQ-880 is a humanized antibody expressed in CHO cells, targeting DKK1. The predicted molecular weight (MW) of BHQ-880 is 142.96 kDa. The isotype control for BHQ-880 can refer to Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P990572

DCBY02 1 Publications Verification	Transmembrane Glycoprotein	Inflammation/Immunology
DCBY02 is a monoclonal antibody targeting CD93 expressed in CHO cells. DCBY02 has a heavy chain of the mlgG type and a light chain of the mkappa type, with a predicted molecular weight (MW) of 150 kDa. The isotype control for DCBY02 can be referenced as Mouse IgG1 kappa, Isotype Control.

HY-P990593

GSK-4381562	Inhibitory Antibodies	Inflammation/Immunology
GSK-4381562 is a CHO-expressed human antibody that targets PVRIG. GSK-4381562 carries a huIgG1 heavy chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for GSK-4381562 can refer to Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P990662

Sapelizumab	Interleukin Related	Inflammation/Immunology
Sapelizumab is a CHO-expressed humanized antibody targeting IL-6Ra/CD126. Sapelizumab has a huIgG2 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for Sapelizumab can refer to Human IgG2 kappa, Isotype Control (HY-P99002).

HY-P990549

ASK-8007	Inhibitory Antibodies	Inflammation/Immunology
ASK-8007 is a humanized antibody expressed by CHO, targeting Osteopontin. ASK-8007 has a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 145.02 kDa. The isotype control for ASK-8007 can refer to Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P990614

LK-1	Myosin	Inflammation/Immunology
LK-1 is a humanized antibody expressed in CHO that targets S100A4. LK-1 carries a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for LK-1 can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).

HY-114128

Turoctocog alfa pegol NN-7088; NN 7170	Factor VIII	Others
Turoctocog alfa pegol is a recombinant coagulation factor VIII (FVIII) from chinese hamster ovary (CHO) cells. Turoctocog alfa pegol can be used for researching haemophilia A .

HY-P99844

Davoceticept ALPN-202; CD80 vIgD-Fc	CTLA-4	Cancer
Davoceticept (ALPN-202; CD80 vIgD-Fc) is a variant CD80 vIgD-Fc fusion protein targeting CTLA-4 and PD-L1. Davoceticept consists of the (1-107) fragment of CD80 linked to IGHG1 Fc via a peptidyl linker. The expression system of Davoceticept is usually CHO (Chinese Hamster Ovary) cells .

HY-P990429

Anti-Hepsin Antibody	Ser/Thr Protease	Inflammation/Immunology
Anti-Hepsin Antibody is a CHO-expressed human antibody that targets Hepcidin.

HY-P990667B

STX-100 (Biotinylated)	Integrin	Inflammation/Immunology
STX-100 (Biotinylated) is a biotin-labeled STX-100 (HY-P990667). STX-100 is a humanized antibody expressed in HEK293 cells, targeting Integrin aVb6 (ITGAV & ITGB6) .

HY-P99892

Serclutamab PR-1594407; DC-1630423	EGFR	Others
Serclutamab is a humanized chimeric antibody targeting EGFR IgG1-κ. Mainly expressed by CHO (Chinese Hamster Ovary) cells .

HY-P99295A

Imgatuzumab (FUT8-KO) RG 7160 (FUT8-KO); RO 5083945 (FUT8-KO); Anti-EGFR Recombinant Antibody (FUT8-KO)	EGFR	Cancer
Imgatuzumab (FUT8-KO) is a humanized monoclonal antibody against EGFR expressed in CHO cells with the fucosyltransferase 8 gene (FUT8) knocked out. Imgatuzumab is an immunomodulator. Imgatuzumab may be used in cancer research.

HY-P9801

Anti-Spike-RBD mAb 1 Publications Verification SARS-CoV-2 (2019-nCoV) Spike RBD Antibody	SARS-CoV	Infection
Anti-Spike-RBD mAb is a CHO cell derived human monoclonal IgG1 antibody. Blocking the interaction of Spike protein and ACE2. Anti-Spike-RBD mAb is a potential therapeutic approach for SARS-CoV-2 treatment .

HY-P990401

Anti-DLL3 Antibody	Inhibitory Antibodies	Inflammation/Immunology
The Anti-DLL3 Antibody is a humanized antibody expressed in CHO, targeting DLL3. The predicted molecular weight (MW) of the Anti-DLL3 Antibody is 146.36 kDa. The isotype control for the Anti-DLL3 Antibody can refer to Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P990560

BNC-101	Inhibitory Antibodies	Inflammation/Immunology
BNC-101 is a human-derived antibody expressed in CHO cells that targets GPR49/LGR5. The predicted molecular weight (MW) of BNC-101 is 145.34 kDa. The isotype control for BNC-101 can refer to Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P990388

Anti-CXADR Antibody	Inhibitory Antibodies	Inflammation/Immunology
Anti-CXADR Antibody is a humanized antibody expressed in CHO, targeting CXADR. The Anti-CXADR Antibody has a huIgG2 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for Anti-CXADR Antibody can refer to Human IgG2 kappa, Isotype Control (HY-P99002).

HY-P990532

Anti-TPBG Antibody	Wnt	Inflammation/Immunology
Anti-TPBG Antibody is a humanized antibody expressed in CHO cells, targeting TPBG. The Anti-TPBG Antibody is composed of a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 145.8 kDa. The isotype control for Anti-TPBG Antibody can refer to Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P99871

Ebronucimab AK102	PCSK9	Others
Ebronucimab (AK102) is an IgG1-λ2 antibody targeting PCSK9 and is primarily expressed by CHO DG44 (Chinese Hamster Ovary) cells .

HY-P9807

Anti-SARS-CoV-2 Spike mAb (CR3022) SARS-CR3022; SARS-CoV-2 Antibody-CR3022	SARS-CoV	Infection Inflammation/Immunology
Anti-SARS-CoV-2 Spike mAb (CR3022) is a a CHO cell derived human monoclonal IgG1 antibody. It binds to both S1 domain of SARS-CoV/SARS-CoV-2 Spike protein .

Species:	Virus (2) Human (108) Porcine (1) Rhesus Macaque (1) Rat (17) Mouse (41) Cynomolgus (3)
Tag:	His (53) Tag Free (91) Avi (2) HA (1) Fc (17)
Source:	CHO (12) CHO (154)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P7086

	*Noggin Protein, Mouse (CHO)* 10+ Cited Publications rMuNoggin; NOG	Mouse	CHO
	Noggin protein is an important BMP inhibitor that plays an indispensable role in the neural tube, somite growth, cartilage morphogenesis, and joint formation. Its homodimeric structure promotes significant interactions with GDF5 and possibly GDF6, inhibiting chondrocyte differentiation. Noggin Protein, Mouse (CHO) is the recombinant mouse-derived Noggin protein, expressed in CHO.

HY-P7051A

	*Noggin Protein, Human (CHO)* 10+ Cited Publications rHuNoggin; NOG	Human	CHO
	Noggin is an antagonist of bone morphogenetic proteins (BMPs) and a member of the TGF-β superfamily, existing as a homodimer. Noggin binds to BMP-2/-4/-7 and inhibits their binding to BMPR-I/II receptors, thereby synergistically inducing bone differentiation in HMSCs, maintaining pluripotency in hESCs, inhibiting angiogenesis in HUVECs, and promoting myelination in oligodendrocytes, exerting neural activity. Noggin Protein, Human (CHO) is a recombinant human Noggin protein expressed in CHO cells with tag-free.

HY-P7359

	*GDNF Protein, Mouse (CHO)* 2 Publications Verification rMuGDNF; GDNF; ATF	Mouse	CHO
	Glial-cell-line-derived neurotrophic factor (GDNF), a neurotrophic factor belongs to the GDNF family ligands (GFLs)., promotes survival of dopamine neurons. GDNF demonstrates a variety of neuroprotective roles for mammalian neurons. GDNF Protein, Mouse (CHO) is produced in CHO cells, and consists of 134 amino acids (S78-I211).

HY-P7088

	*TPO/Thrombopoietin Protein, Mouse (CHO)* 1 Publications Verification rMuTPO; TPO	Mouse	CHO
	TPO Protein, Mouse (CHO) is a hematopoietic factor that controls platelet production.

HY-P7121

	*HGF Protein, Human (CHO)* 5+ Cited Publications rHuHGF; Hepatopoietin-A; SF	Human	CHO
	Human hepatocyte growth factor (HGF) is a natural ligand of Met tyrosine kinase receptor, mediating cell proliferation, migration and anti-apoptosis by binding to Met receptor. HGF protein can promote the regeneration of liver and kidney cells, regulate extracellular matrix metabolism (inhibit TGF-β, promote MMP-2), and is used in the study of acute and chronic kidney disease, liver fibrosis and other diseases. HGF Protein, Human (CHO) is a recombinant human HGF protein expressed by CHO cells with tag-free.

HY-P7030A

	*IL-10 Protein, Human (CHO)* 4 Publications Verification rHuIL-10; CSIF	Human	CHO
	IL-10 Protein, Human (CHO) is a CHO cell derived anti-inflammatory, immunomodulatory cytokine that regulates mucosal inflammation.

HY-P7098A

	*IL-10 Protein, Rat (CHO)* 2 Publications Verification rRtIL-10; CSIF	Rat	CHO
	IL-10 Protein, Rat (CHO) is a CHO cell derived immunosuppressive cytokine produced by a variety of mammalian cell types including macophages, monocytes, B-cells, T-cells and keratinocytes.

HY-P7164

	*Erythropoietin/EPO Protein, Human (CHO)* 2 Publications Verification rHuEPO; Epoetin; EPO	Human	CHO
	Erythropoietin/EPO is a renal cytokine that activates Akt and NF-κB signaling pathways by binding to erythroid progenitor cells EPOR. Erythropoietin/EPO regulates erythroid proliferation and differentiation and inhibits apoptosis. Erythropoietin/EPO also has angiogenic ability comparable to VEGF and can stimulate endothelial cell capillary sprouting. Erythropoietin/EPO can be used in the study of ischemic heart diseases such as anemia in end-stage renal disease. Erythropoietin/EPO Protein, Human (CHO) is a recombinant Erythropoietin/EPO protein expressed in CHO cells with tag-free.

HY-P700011

	*Klotho Protein, Human (CHO, His)* 1 Publications Verification α-Klotho	Human	CHO
	Klotho Protein exhibits weak glycosidase activity against glucuronidated steroids and is inactive in vivo due to the lack of essential active site Glu residues. It regulates calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D. Klotho Protein, Human (CHO, His) is the recombinant human-derived Klotho protein, expressed by CHO , with C-10*His labeled tag.

HY-P7074A

	*IL-10 Protein, Mouse (CHO)* rMuIL-10; CSIF	Mouse	CHO
	IL-10 Protein, Mouse (CHO) is a potent CHO cell derived anti-inflammatory cytokine results in increased immune-mediated demyelination in mice infected with a neurotropic coronavirus.

HY-P7288

	*SHH Protein, Mouse (CHO)* rMuShh; HHG-1; ShhNC	Mouse	CHO
	SHH Protein, Mouse (CHO) is a morphogenic factor that actively orchestrates many aspects of cerebellar development and maturation.

HY-P705544

	*BMP-4 Protein, Human (CHO)* BMP-2B	Human	CHO
	Bone morphogenetic protein 4 (BMP-4) is a polymorphic ligand protein belonging to the TGF-β family, which is involved in the circulation of the vascular system and can activate receptors on vascular cells. BMP-4 binds to type I receptors (ALK-2/-3/-6) and type II receptors (BMPR2, ACVR2A) to increase plaque formation and promote oxidative stress, endothelial dysfunction, and osteogenic differentiation through its pro-inflammatory and pro-atherogenic effects. BMP-4 Protein, Human (CHO) has a total length of 116 amino acids (S293-R408), is expressed in CHO cells with tag free.

HY-P7101A

	*IL-4 Protein, Rat (CHO, His)* rRtIL-4, His (CHO-expressed); BSF-1; Binetrakin; Lymphocyte stimulatory factor 1; Pitrakinra	Rat	CHO
	IL-4 Protein, Rat (CHO,His) is a potent CHO cell derived lymphoid cell growth factor, which stimulates the growth and survivability of B-cells and T-cells.

HY-P7033

	*IL-13 Protein, Human (CHO)* 5+ Cited Publications rHuIL-13; NC30	Human	CHO
	IL-13 Protein, Human (CHO) is a CHO cell derived cytokine which affects the morphology, growth, and surface antigen expression and phenotype of monocytes and elicits B cell proliferation.

HY-P79236

	*Agrin Protein, Human (CHO, His)* 2 Publications Verification agrin proteoglycan; Agrin; AGRN	Human	CHO
	Agrin is critical for neuromuscular junction development and was discovered in mouse knockout studies. It contains laminin G, Kazal-type serpin, and epidermal growth factor domains. Agrin Protein, Human (CHO, His) is the recombinant human-derived Agrin protein, expressed by CHO , with N-6*His labeled tag.

HY-P7208

	*IL-12 Protein, Mouse (CHO)* rMuIL-12; NKSF; CLMF	Mouse	CHO
	IL-12 Protein, Mouse (CHO) has both T cell growth and IFN-γ stimulatory properties.

HY-P7115A

	*TPO/Thrombopoietin Protein, Human (CHO, His)* rHuThrombopoietin/TPO; TPO	Human	CHO
	TPO/Thrombopoietin Protein, Human (CHO, His), also called megakaryocyte growth and development factor, is a cytokine that regulates megakaryocyte and platelet production.

HY-P7247

	*M-CSF Protein, Rat (CHO)* 5+ Cited Publications rRtM-CSF; CSF1; MCSF	Rat	CHO
	M-CSF Protein, Rat (CHO) is a pro-inflammatory cytokine which binds to its receptor CSF1R, and is involved in the development and proliferation of cells of the monocyte/macrophage lineage and participates in the induction of osteoclasts.

HY-P7311

	*VEGF164 Protein, Rat (CHO)* 3 Publications Verification rRtVEGF164; VEGF-AA; VPF	Rat	CHO
	VEGF164 Protein, Rat (CHO) is a potent mediator of angiogenesis and binds the semaphorin receptor, neuropilin1.

HY-P7092A

	*EGF Protein, Rat (CHO)* rRtEGF; Pro-epidermal growth factor; Urogastrone	Rat	CHO
	EGF Protein, Rat (CHO) is a potent epidermal growth factor, promotes epithelial proliferation and migration, and increases epithelial wound closure and shortens healing time.

HY-P7102A

	*IL-5 Protein, Rat (CHO)* rRtIL-5; EDF; BCDFII; TRF	Rat	CHO
	IL-5 Protein, Rat (CHO), a CHO cell derived cytokine, stimulates B cell growth and increases immunoglobulin secretion.

HY-P7115

	*TPO/Thrombopoietin Protein, Human (CHO, His, solution)* rHuThrombopoietin/TPO; TPO	Human	CHO
	TPO/Thrombopoietin Protein, Human (CHO, His, solution), also called megakaryocyte growth and development factor, is a cytokine that regulates megakaryocyte and platelet production.

HY-P7043A

	*IL-5 Protein, Human (CHO)* rHuIL-5; EDF; BCDFII; TRF	Human	CHO
	IL-5 Protein, Human (CHO) is a selective activator of human eosinophil function.

HY-P7081A

	*IL-5 Protein, Mouse (CHO)* rMuIL-5; EDF; BCDFII; TRF	Mouse	CHO
	IL-5 Protein, Mouse (CHO) is a CHO cell derived hematopoietic growth factor expressed in Th2, mast cells and eosinophils.

HY-P79253

	*Cerebellin-2 Protein, Human (CHO, HA)* Cerebellin-2; CBLN2	Human	CHO
	The protein Cerebellin-2 organizes synapses in specific brain neurons, which is critical for long-term maintenance. It forms homohexamers composed of disulfide-bonded homotrimers connected through the C1q domain. Cerebellin-2 Protein, Human (CHO, HA) is the recombinant human-derived Cerebellin-2 protein, expressed by CHO , with N-HA labeled tag.

HY-P7085A

	*M-CSF Protein, Mouse (CHO)* 5+ Cited Publications rMuM-CSF; CSF-1; MGI-IM	Mouse	CHO
	M-CSF Protein, Mouse (CHO) is a pro-inflammatory cytokine, binds to its receptor CSF1R, and is involved in the development and proliferation of cells of the monocyte/macrophage lineage and participates in the induction of osteoclasts which are important in the destruction of bone and cartilage and in the periarticular osteoporotic changes.

HY-P7050A

	*M-CSF Protein, Human (CHO)* 5+ Cited Publications rHuM-CSF; CSF-1; MGI-IM	Human	CHO
	M-CSF (CSF-1) protein is a homodimeric hematopoietic growth factor and proinflammatory cytokine, belonging to the colony stimulating factor. M-CSF can act specifically on the monocyte-macrophage lineage, drive monocyte proliferation and differentiation into macrophages/osteoclasts, and induce M1 macrophages to enhance ADCC anti-tumor activity and M2 macrophages to promote VEGF angiogenesis. M-CSF Protein, Human (CHO) is a recombinant human M-CSF protein expressed in CHO cells with tag-free.

HY-P7154

	*DKK-1 Protein, Mouse (CHO)* 5 Publications Verification rMuDKK-1; mDkk-1; Dickkopf-1	Mouse	CHO
	Dkk-1 Protein, Mouse (CHO) is shown to be a potent inhibitor of Wnt signaling and member of dickkopf family.

HY-P7076A

	*IL-13 Protein, Mouse (CHO, His)* 3 Publications Verification rMuIL-13, His; P600	Mouse	CHO
	IL-13 Protein, Mouse (CHO, His), an important CHO cell derived cytokine, is a multifunctional cytokine whose principal action is to diminish inflammatory responses.

HY-P7031A

	*IL-11 Protein, Human (CHO)* 1 Publications Verification rHuIL-11; Adipogenesis inhibitory factor; AGIF	Human	CHO
	IL-11 Protein, Human (CHO) is a CHO cell derived protective factor, which has a protective role and can accelerate recovery of platelets, and remarkably lessen the extent of inflammatory responses.

HY-P7149

	*Cardiotrophin-1/CTF1 Protein, Human (CHO)* rHuCT-1; CTF1	Human	CHO
	Cardiotrophin-1/CTF1 Protein, Human (CHO), a member of IL-6 family of cytokines, is a key regulator of energy homeostasis and of glucose and lipid metabolism.

HY-P7219

	*IL-4 Protein, Porcine (CHO)* rPoIL-4; BSF-1; IL4	Porcine	CHO
	IL-4 Protein, Porcine (CHO) is the prime anti-infalmmatory cytokine involves in cell proliferation, various gene expression and avert apoptosis in IL-4 expressing cells.

HY-P7296

	*TGF alpha/TGFA Protein, Human (CHO)* rHuTGF-α; ETGF; TGFA	Human	CHO
	TGF-alpha Protein, Human (CHO) is a potent angiogenic mediator and mitogenic polypeptide.

HY-P7345

	*FGF-21 Protein, Human (CHO, His)* rHuFGF-21, His; FGF21	Human	CHO
	FGF-21 Protein, Human (CHO, His) is a polypeptide chain containing the C-termimal His tag produced in CHO cells.FGF-21 Protein, Human (CHO, His) is a member of the ﬁbroblast growth factor (FGF) subfamily, acts as a metabolic regulator with pleiotropic effects.

HY-P7025A

	*IFN-gamma Protein, Human (CHO)* 5+ Cited Publications rHuIFN-γ; IFNG; IFN-gamma; Interferon gamma	Human	CHO
	IFN-gamma Protein, Human (CHO) is a cytokine with potent immunomodulatory, antiviral and antitumor activities.

HY-P7095A

	*IFN-gamma Protein, Rat (CHO)* rRtIFN-γ; IFNG; IFN-gamma; Interferon gamma	Rat	CHO
	IFN-gamma Protein, Rat (CHO) is a pro-inflammatory cytokine with potent immunomodulatory, anti-proliferative, and antiviral properties.

HY-P7116

	*BDNF Protein, Human/Mouse/Rat (CHO)* BDNF/Brain-derived neurotrophic factor; Abrineurin	Mouse;Human;Rat	CHO
	BDNF Protein, Human (CHO) is a neurotrophin binding to the high-affinity tropomyosin-related receptor kinase B (TrkB) receptor to regulate neurodevelopmental processes, including neuronal survival, neuronal differentiation, and synaptic plasticity.

HY-P72828

	*Angiopoietin-2 Protein, Human (CHO, His)* Angiopoietin-2; ANG-2; ANGPT2	Human	CHO
	Angiopoietin-2 (ANGPT2) protein competes with ANGPT1 for TEK/TIE2 binding, modulates ANGPT1 signaling and induces TEK/TIE2 phosphorylation even in the absence of ANGPT1. In the absence of angiogenic stimulation, ANGPT2 disrupts cell-matrix contacts, potentially triggering endothelial cell apoptosis and vessel regression. Angiopoietin-2 Protein, Human (CHO, His) is the recombinant human-derived Angiopoietin-2 protein, expressed by CHO , with C-6*His labeled tag.

HY-P74148

	*Follistatin/FST Protein, Mouse (CHO, Fc)* Follistatin; FS; Activin-binding protein; FST	Mouse	CHO
	Follistatin (FST) is a regulator of TGFβ family signaling and acts by selectively binding to TGFβ family ligands and preventing ligand binding to the receptor complex. Follistatin has the ability to suppress the follicle stimulating hormone (FSH). Follistatin/FST Protein, Mouse (CHO, Fc) is produced in CHO cells with a C-Terminal Fc-tag. It consists of 317 amino acids (M1-N317).

HY-P79343

	*Agrin Protein, Human (1073a.a, CHO, His)* agrin proteoglycan; Agrin; AGRN	Human	CHO
	Agrin is a heparan sulfate basal glycoprotein that is critical for the formation and maintenance of the neuromuscular junction (NMJ). It forms the AGRN-LRP4 receptor complex, activates MUSK and regulates gene transcription and AChR clusters in the postsynaptic membrane to form the NMJ. Agrin Protein, Human (1073a.a, CHO, His) is the recombinant human-derived Agrin protein, expressed by CHO , with C-6*His labeled tag.

HY-P704354

	*Angiopoietin-2 Protein, Mouse (CHO, His)* Angiopoietin-2; ANG-2; ANGPT2	Mouse	CHO
	Angiopoietin 2 protein (ANGPT2) binds to TEK/TIE2, competes with ANGPT1, and modulates its signaling. Even in the absence of ANGPT1, ANGPT2 induces TEK/TIE2 phosphorylation. Angiopoietin-2 Protein, Mouse (CHO, His) is the recombinant mouse-derived Angiopoietin-2 protein, expressed by CHO, with C-His labeled tag.

HY-P705545

	*Integrin alpha D beta 2 Protein, Human (CHO, His)*	Human	CHO

HY-P73128

	*IFN-beta Protein, Human (CHO)* 4 Publications Verification Interferon beta; IFN-beta; IFNB1; IFB; IFNB	Human	CHO
	IFN-beta is a secretory cytokine produced by cells under viral infection or nucleic acid stimulation. IFNβ binds to cell surface heterodimeric receptors (IFNAR1/IFNAR2), activates the JAK-STAT signaling pathway, and induces the expression of interferon-stimulated genes (ISGs) (such as PKR, 2'5'-OAS). IFN-beta inhibits viral proliferation, regulates immune responses (such as inhibiting Th1 cell polarization, reducing pro-inflammatory cytokine secretion), inhibits the proliferation of vascular smooth muscle cells and tumor cells. IFN-beta has anti-atherosclerotic and vascular remodeling effects. IFN-beta Protein, Human (CHO) is a recombinant interferon-beta protein (CHO), expressed by CHO, without a tag.

HY-P7280

	*PDGF-DD Protein, Human (CHO)* 3 Publications Verification rHuPDGF-DD; Platelet-derived growth factor D; SCDGFB	Human	CHO
	PDGF-DD Protein, Human (CHO) is a member of the PDGF family, specifically binds to and activates its cognate receptor PDGFR-β, and participates in regulating cancer proliferation, transformation, and invasion through activating multiple downstream oncogenic pathways, resulting in tumor development and progression.

HY-P701101

	*M-CSF Protein, Human (CHO,Tag Free)* 1 Publications Verification rHuM-CSF; CSF-1; MGI-IM	Human	CHO
	M-CSF Protein, Human (CHO) is a hematopoietic growth factor with various glycosylation sites, affects survival and function of the tissue macrophages, and possesses antitumor activity.

HY-P7314

	*VEGF-D Protein, Human (CHO)* rHuVEGF-D; Vascular endothelial growth factor D; FIGF	Human	CHO
	VEGF-D Protein, Human (CHO) is a regulator of both angiogenesis and lymphangiogenesis.

HY-P7344

	*FGF-16 Protein, Human (CHO)* rHuFGF-16; FGF-16; Fibroblast Growth Factor-16	Human	CHO
	FGF-16 Protein, Human (CHO) is a polypeptide chain containing 206 amino acids produced in CHO cells. FGF-16 is a heparin binding growth factor, a member of the FGF family.

HY-P7400

	*HB-EGF Protein, Human (CHO)* 3 Publications Verification rHuProheparin-binding EGF-like Growth Factor; DTR; DTS; HEGFL	Human	CHO
	HB-EGF Protein, Human (CHO) is shown to play a role in wound healing, cardiac hypertrophy, and heart development and function.

HY-P7211

	*IL-18BP Protein, Human (CHO)* 2 Publications Verification rHuIL-18BP; Tadekinig-alfa; IL18BP	Human	CHO
	IL-18BP Protein, Human (CHO) Binding Protein (CHO-expressed) is a modulator of the Th1 cytokine response.

HY-P7372

	*IL-17A Protein, Mouse (CHO)* 2 Publications Verification rMuIL-17A; CTLA-8; IL-17A	Mouse	CHO
	IL-17A is a homodimeric cytokine and plays a critical role in host defense mechanisms against many bacterial and fungal pathogens as well as allergic and autoimmune responses. IL-17A induces the production of antimicrobial peptides, cytokines, chemokines, and matrix metalloproteinases. IL-17A Protein, Mouse (CHO) is a recombinant mouse IL-17A protein and is expressed in CHO cells. It consists of 133 amino acids (A26-A158).

Compare Products


Products	In-stock - + Add to Cart
Cat. No.
Species
Source
Tag
Accession
Gene ID
Molecular Weight
Purity
Endotoxin Level
Biological Activity
Appearance
Formulation
Storage & Stability
Shipping
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Host:	Rabbit (2)
Reactivity:	Human (2)
Application:	WB (2)
Isotype:	IgG (2)
Conjugation:	Non-conjugated (2) Biotin (3)
Clonality:	Monoclonal (1) Recombinant (1)
Modification:	Unmodified (1)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P83488

	MKLP1 Antibody (YA3233) CHO1; KNSL5; MKLP1; MKLP-1	WB	Human
	MKLP1 Antibody (YA3233) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MKLP1.

HY-P83488A

	MKLP1 Antibody (YA3233)(PBS only) CHO1; KNSL5; MKLP1; MKLP-1	WB	Human
	MKLP1 Antibody (YA3233) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MKLP1.

Compare Products


Products	In-stock - + Add to Cart
Cat. No.
Host
Reactivity
Application
Dilution Ratio
Molecular Weight
Conjugation
Clonality
Immunogen
Appearance
Isotype
Gene ID
SwissProt ID
Purity
Formulation
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name		Classification

HY-W588725A

*N3-Cho* bromide** 1 Publications Verification Azido-CHOline bromide		Azide
N3-Cho (Azido-choline) bromide is a click chemistry reagent containing an azide group that can be used in the synthesis of cell membrane structures .

HY-135957

2'-Azido-2'-deoxyuridine N3dUrd		Azide
2'-Azido-2'-deoxyuridine (N3dUrd) is a ribonucleotide reductase inhibitor. 2'-Azido-2'-deoxyuridine has anti-cancer activity . 2'-Azido-2'-deoxyuridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-140633

Ald-C2-PEG4-azide N3-PEG4-CH2CH2CHO		PROTAC Synthesis Azide
Ald-C2-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Ald-C2-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-W895360

pacFA		Alkynes
pacFA is a bifunctional fatty acid with both photocrosslinking and click chemistry properties. pacFA can be metabolically incorporated into phospholipids by cells, enabling in-situ capture, identification and imaging of protein-lipid interactions in live cells and living organisms via ultraviolet crosslinking and click reactions .

Cat. No.	Product Name		Classification

HY-176509A

DSPE-PEG2000-CHO		Pegylated Lipids
DSPE-PEG2000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG2000-CHO can be used for drug delivery .

HY-176509C

DSPE-PEG5000-CHO		Pegylated Lipids
DSPE-PEG5000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG5000-CHO can be used for drug delivery .

HY-176509

DSPE-PEG1000-CHO		Pegylated Lipids
DSPE-PEG1000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG1000-CHO can be used for drug delivery .

HY-152656

2-Hydrazinyl-adenosine		Nucleoside Analogs Adenosine
2-Hydrazinyl-adenosine is a synthetic intermediate. Derivatives of 2-Hydrazinyl-adenosine act as A_2A adenosine receptor agonists. 2-Hydrazinyl-adenosine is used in the research of neurodegenerative diseases .

HY-155921

mPEG5000-CHO mPEG5000-Aldehyde		Polymers
mPEG5000-CHO participates in the formation of a three-dimensional porous scaffold which carries active substances to form a delivery vehicle. The -CHO functional group interacts with the -NH2 functional group of the chitosan chain to form a glutaraldehyde-type adduct to functionalize mPEG. This functionalization and cross-linking can affect the rigidity of the delivery system, allowing slow release of the cross-linked conjugate system.

HY-138912

Cho-Arg TFA		Cholesterol
Cho-Arg TFA is a steroid-based cationic lipid with an L-Arginine headgroup. Cho-Arg TFA shows a remarkably high optimized plasmid DNA transfection efficacy .

HY-158709

Cho-es-Lys		Cholesterol
Cho-es-Lys is a cationic lipid synthesized by coupling natural cholesterol and amino acids, which has high gene transfection efficiency. Cho-es-Lys can be used in drug delivery research .

HY-176509D

DSPE-PEG10000-CHO		Pegylated Lipids
DSPE-PEG10000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG10000-CHO can be used for drug delivery .

HY-176509B

DSPE-PEG3400-CHO		Pegylated Lipids
DSPE-PEG3400-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG3400-CHO can be used for drug delivery .

HY-176509H

DSPE-PEG40000-CHO		Pegylated Lipids
DSPE-PEG40000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG40000-CHO can be used for drug delivery .

HY-155922

mPEG10000-CHO mPEG10000-Aldehyde		Polymers
mPEG10000-CHO participates in the formation of a three-dimensional porous scaffold which carries active substances to form a delivery vehicle. The -CHO functional group interacts with the -NH2 functional group of the chitosan chain to form a glutaraldehyde-type adduct to functionalize mPEG. This functionalization and cross-linking can affect the rigidity of the delivery system, allowing slow release of the cross-linked conjugate system.

HY-155919

mPEG2000-CHO mPEG2000-Aldehyde		Polymers
mPEG2000-CHO participates in the formation of a three-dimensional porous scaffold which carries active substances to form a delivery vehicle. The -CHO functional group interacts with the -NH2 functional group of the chitosan chain to form a glutaraldehyde-type adduct to functionalize mPEG. This functionalization and cross-linking can affect the rigidity of the delivery system, allowing slow release of the cross-linked conjugate system.

HY-155918

mPEG1000-CHO mPEG1000-Aldehyde		Polymers
mPEG1000-CHO participates in the formation of a three-dimensional porous scaffold that carries active substances to form a delivery vehicle. The -CHO functional group interacts with the -NH2 functional group of the chitosan chain to form a glutaraldehyde-type adduct to functionalize mPEG. This functionalization and cross-linking can affect the rigidity of the delivery system, allowing slow release of the cross-linked conjugate system.

HY-138913

*2H-Cho-Arg TFA*		Cholesterol
2H-Cho-Arg (TFA) is a steroid-based cationic lipid that contains a 2H-cholesterol skeleton coupled to an L-arginine head group and can be used to facilitate gene transfection.

HY-176509E

DSPE-PEG20000-CHO		Pegylated Lipids
DSPE-PEG20000-CHO is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG20000-CHO can be used for drug delivery .

HY-155923

mPEG20000-CHO mPEG20000-Aldehyde		Polymers
mPEG20000-CHO participates in the formation of a three-dimensional porous scaffold which carries active substances to form a delivery vehicle. The -CHO functional group interacts with the -NH2 functional group of the chitosan chain to form a glutaraldehyde-type adduct to functionalize mPEG. This functionalization and cross-linking can affect the rigidity of the delivery system, allowing slow release of the cross-linked conjugate system.

HY-RS19540

Col11a1 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Col11a1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Col11a1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

CHO

Inhibitors & Agonists

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

MCE Kits

Inhibitory Antibodies

NaturalProducts

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Oligonucleotides

GMP Molecules

Natural
Products