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broad-spectrum

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0525A

Carbenicillin disodium 5+ Cited Publications Sodium carbenicillin	Antibiotic Bacterial	Infection
Carbenicillin disodium (Sodium carbenicillin) is a broad-spectrum semi-synthetic penicillin antibiotic for gram-negative bacteria. Carbenicillin disodium can interfere the cell wall synthesis while displaying low toxicity to plant tissue .

HY-B0474

Tetracycline hydrochloride 50+ Cited Publications	Environmental Pollutants Antibiotic Bacterial	Infection Cancer
Tetracycline hydrochloride is a broad-spectrum antibiotic with oral activity. Tetracycline hydrochloride exhibits activity against a wide range of bacteria including gram-positive, gram-negative bacteria, chlamydiae, mycoplasmas and rickettsiae. Tetracycline hydrochloride can be used for the research of infections .

HY-A0107

Tetracycline 50+ Cited Publications	Antibiotic Bacterial	Infection Cancer
Tetracycline is a broad-spectrum antibiotic with oral activity. Tetracycline exhibits activity against a wide range of bacteria including gram-positive, gram-negative bacteria, chlamydiae, mycoplasmas and rickettsiae. Tetracycline can be used for the research of infections .

HY-76200

Voriconazole 10+ Cited Publications UK-109496	Fungal Bacterial	Infection Neurological Disease Cancer
Voriconazole (UK-109496) is a second-generation, broad-spectrum triazole antifungal agent that inhibits fungal ergosterol biosynthesis. Voriconazole exerts its antifungal activity by inhibition of 14-α-lanosterol demethylation, which is mediated by fungal cytochrome P450 enzymes. Voriconazole can penetrate the blood brain barrier (BBB) .

HY-17373

Posaconazole 10+ Cited Publications SCH 56592	Fungal Parasite	Infection Cancer
Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity.

HY-B0438

Spectinomycin dihydrochloride 3 Publications Verification	Bacterial Antibiotic	Infection
Spectinomycin dihydrochloride is a broad-spectrum antibiotic and inhibits the growth of a variety of gram-positive and gram-negative organisms. Spectinomycin dihydrochloride acts by selectively targeting to the bacterial ribosome and interrupting protein synthesis. Spectinomycin dihydrochloride is also a noncompetitive inhibitor of td intron RNA with an K_i value of 7.2 mM ^- .

HY-16980A

Eravacycline dihydrochloride 25+ Cited Publications TP-434 dihydrochloride; TP-434-046	Beta-lactamase Bacterial	Infection
Eravacycline dihydrochloride (TP-434 dihydrochloride) is a potent and broad-spectrum antibacterial agent.

HY-18233

Manogepix 4 Publications Verification E1210; APX001A	Fungal	Infection
Manogepix (E1210) is a first-in-class, broad-spectrum and orally active antifungal. Manogepix has a mechanism of action-inhibition of fungal glycosylphosphatidylinositol (GPI) biosynthesis .

HY-W017162

DL-3-Phenyllactic acid 2 Publications Verification	Endogenous Metabolite Bacterial	Infection
DL-3-Phenyllactic acid is a broad-spectrum antimicrobial compound.

HY-122609

XO44 PF-6808472	CDK	Cancer
XO44 (PF-6808472) is a broad-spectrum covalent kinase probe. XO44 can bind in CDK2 and CDK1. XO44 also labels CDK4 proteins in cells .

HY-122122

ML-60218 5+ Cited Publications	DNA/RNA Synthesis	Infection Cancer
ML-60218 is a broad-spectrum RNA pol III inhibitor, with IC₅₀s of 32 and 27 μM for Saccharomyces cerevisiae and human. ML-60218 disrupts already assembled viroplasms and to hamper the formation of new ones without the need for de novo transcription of cellular RNAs .

HY-103251

PF-5081090 LpxC-4	Antibiotic Bacterial	Infection
PF-5081090 (LpxC-4) is a potent LpxC inhibitor, is a rapidly bactericidal with broad-spectrum activity. PF-5081090 serves as a regulator of lipid A biosynthesis in Gram-negative pathogens .

HY-10969

Obatoclax Mesylate 10+ Cited Publications GX15-070 Mesylate	Bcl-2 Family Autophagy Parasite	Infection Cancer
Obatoclax Mesylate (GX15-070 Mesylate), a BH3 mimetic, is a pan-BCL-2 family proteins inhibitor with a K_i of 220 nM for BCL-2 . Obatoclax Mesylate induces autophagy-dependent cell death and targets cyclin D1 for proteasomal degradation. Obatoclax Mesylate has anti-cancer and broad-spectrum antiparasitic activity .

HY-101476

Emodepside 1 Publications Verification Bay 44-4400	Parasite	Infection
Emodepside (PF 1022-221) is a cyclooctadepsipeptide with broad-spectrum anthelmintic activity.

HY-B1790

Terconazole R42470	Fungal	Infection
Terconazole is a broad-spectrum antifungal medication for the treatment of vaginal yeast infection.

HY-B2072A

Cephaloridine hydrate	Antibiotic Bacterial	Infection
Cephaloridine hydrate is a broad-spectrum antibacterial antibiotic. Cephaloridine has certain dose-related nephrotoxicity .

HY-106922A

Sanfetrinem sodium GV104326 sodium	Antibiotic Bacterial	Infection
Sanfetrinem (GV104326) sodium is a beta-lactamase-stable antibiotic. Sanfetrinem sodium has broad-spectrum activity against gram-positive and gram-negative bacteria .

HY-A0153A

Cephapirin sodium Cefapirin sodium	Bacterial Antibiotic	Infection
Cephapirin sodium (Cefapirin sodium) is an ephalosporin antibiotic with broad-spectrum antimicrobial activity .

HY-12318G

IBMX 3-Isobutyl-1-methylxanthine; Isobutylmethylxanthine	Phosphodiesterase (PDE)	Inflammation/Immunology
IBMX (3-Isobutyl-1-methylxanthine) (GMP) is IBMX (HY-12318) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. IBMX is a broad-spectrum phosphodiesterase (PDE) inhibitor .

HY-15670

BMS-906024 3 Publications Verification	γ-secretase Notch	Cancer
BMS-906024 is an orally active and selective γ-secretase (gamma secretase) inhibitor. BMS-906024 is a potent pan-Notch receptors inhibitor with IC₅₀s of 1.6 nM, 0.7 nM, 3.4 nM, and 2.9 nM for Notch1, -2, -3, and -4 receptors, respectively. BMS-906024 demonstrates broad-spectrum antineoplastic activity .

HY-106339

Lymecycline 1 Publications Verification Mucomycin	Bacterial	Infection Inflammation/Immunology
Lymecycline is a tetracycline derivative, with broad-spectrum antibacterial activity and also has anti-inflammatory property.

HY-111023

Nemonoxacin malate 1 Publications Verification TG-873870 malate	Antibiotic Bacterial	Infection
Nemonoxacin (TG-873870) malate is a nonfluorinated quinolone antibiotic. Nemonoxacin malate has broad-spectrum activity against Gram-positive, Gram-negative and atypical pathogens. Nemonoxacin malate can inhibit drug-resistant Streptococcus pneumoniae and Methicillin-resistant Staphylococcus aureus. Nemonoxacin malate can be used for the research of community-acquired pneumonia .

HY-B1828

Spectinomycin	Antibiotic Bacterial	Infection
Spectinomycin is a broad-spectrum antibiotic and inhibits the growth of a variety of gram-positive and gram-negative organisms. Spectinomycin acts by selectively targeting to the bacterial ribosome and interrupting protein synthesis. Spectinomycin is also a noncompetitive inhibitor of td intron RNA .

HY-B0525

Carbenicillin	Antibiotic Bacterial	Infection
Carbenicillin is a broad-spectrum semi-synthetic penicillin antibiotic for gram-negative bacteria. Carbenicillin can interfere the cell wall synthesis while displaying low toxicity to plant tissue .

HY-B1354

Cefpiramide SM-1652 free acid; Wy-44635 free acid	Beta-lactamase Antibiotic Bacterial	Infection
Cefpiramide (SM-1652) free acid is a semisynthetic cephalosporin with broad-spectrum antibacterial activity. Cefpiramide free acid shows strong antibacterial effect on both gram-positive bacteria and gram-negative bacteria. Cefpiramide free acid is moderately susceptible to β-lactamase .

HY-B0159

Balofloxacin Q-35	Bacterial Antibiotic	Infection
Balofloxacin (Q-35) is an orally active fluoroquinolone antibiotic with broad-spectrum antibacterial activity against gram-negative, gram-positive, and anaerobic bacteria. Balofloxacin can be used for the research of respiratory, intestinal, and urinary tract infections .

HY-N7062

JNJ-1661010 Takeda-25	FAAH	Neurological Disease
JNJ-1661010 (Takeda-25) a potent and selective fatty acid amide hydrolase (FAAH) inhibitor with IC₅₀s of 34 and 33 nM for rat FAAH and human FAAH, respectively. JNJ-1661010 can cross the blood-brain barrier and used as broad-spectrum analgesics .

HY-B1166

Cefamandole nafate Cefamandole formate sodium	Bacterial Antibiotic	Infection Inflammation/Immunology
Cefamandole nafate (Cefamandole formate sodium) is a second-generation broad-spectrum cephalosporin antibiotic .

HY-114750

Mebendazole-amine	Drug Metabolite	Infection
Mebendazole-amine is a metabolite of Mebendazole (HY-17595). Mebendazole is a broad-spectrum benzimidazole anthelmintic .

HY-16980

Eravacycline TP-434	Beta-lactamase Bacterial Antibiotic	Infection
Eravacycline is a potent and broad-spectrum antibacterial agent.

HY-B0479S

Thiamphenicol-d3 Thiophenicol-d₃; Dextrosulphenidol-d₃	Isotope-Labeled Compounds Bacterial Antibiotic	Infection
Thiamphenicol-d₃ is a deuterium labeled Thiamphenicol. Thiamphenicol, a methyl-sulfonyl derivative of Chloramphenicol, is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit, leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative, Gram-positive aerobic and anaerobic bacteria) .

HY-A0153

Cephapirin Cefapirin	Antibiotic Bacterial	Infection
Cephapirin (Cefapirin) is an ephalosporin antibiotic with broad-spectrum antimicrobial activity .

HY-10969A

Obatoclax 10+ Cited Publications GX15-070	Bcl-2 Family Autophagy Parasite	Infection Cancer
Obatoclax (GX15-070), a BH3 mimetic, is a pan-BCL-2 family proteins inhibitor with a K_i of 220 nM for BCL-2 . Obatoclax induces autophagy-dependent cell death and targets cyclin D1 for proteasomal degradation. Obatoclax has anti-cancer and broad-spectrum antiparasitic activity .

HY-108880

Carindacillin sodium Carbenicillin indanyl sodium; CP-15464-2	Bacterial	Infection
Carindacillin (Carbenicillin indanyl) sodium is an orally active and broad-spectrum antimicrobial agent. Carindacillin sodium can be hydrolyzed to Carbenicillin in vivo. Carindacillin sodium can be used for the research of urinary-tract infection .

HY-A0107R

Tetracycline (Standard)	Reference Standards Bacterial Antibiotic	Infection Cancer
Tetracycline (Standard) is the analytical standard of Tetracycline. This product is intended for research and analytical applications. Tetracycline is a broad-spectrum antibiotic with oral activity. Tetracycline exhibits activity against a wide range of bacteria including gram-positive, gram-negative bacteria, chlamydiae, mycoplasmas and rickettsiae. Tetracycline can be used for the research of infections .

HY-B0414

Fleroxacin 1 Publications Verification RO 23-6240; AM-833	Bacterial Antibiotic	Infection
Fleroxacin (RO 23-6240) is a broad-spectrum antimicrobial fluoroquinolone.

HY-137927

Benapenem	Antibiotic	Others
Benapenem is a carbapenem-type agent that belongs to the broad-spectrum β-lactam antibiotic class.

HY-W516735

Sedaxane	Fungal Succinate Dehydrogenase	Infection
Sedaxane is a new broad-spectrum seed treatment fungicide. Sedaxane inhibits fungal respiration by binding to the succinate dehydrogenase complex in fungal mitochondria. Sedaxane has broad-spectrum activity against a variety of seed-borne and soil-borne fungi. Sedaxane can be used in the study of barley loose smut and barley stripe disease .

HY-N7111

Sultamicillin tosylate Sultamicillin (tosilate)	Bacterial Antibiotic	Infection
Sultamicillin tosylate is a broad-spectrum and orally active beta-lactamase inhibitor, an antibiotic with antibacterial activity .

HY-N7115

Sultamicillin	Bacterial Antibiotic	Infection
Sultamicillin is a broad-spectrum and orally active beta-lactamase inhibitor, an antibiotic with antibacterial activity .

HY-132282

Thiamphenicol glycinate hydrochloride	Bacterial	Infection
Thiamphenicol glycinate hydrochloride is a broad-spectrum antibacterial agent that can be used for respiratory tract infections research .

HY-108504

Co 102862 V 102862	Sodium Channel	Neurological Disease
Co 102862 (V 102862) is a potent, broad-spectrum, state-dependent Na ⁺ channel blocker. Co 102862 is also an orally active anticonvulsant .

HY-14762

Besifloxacin	Antibiotic Bacterial	Infection
Besifloxacin is a fluoroquinolone antimicrobial agent. Besifloxacin can inhibit cytokine production by monocytes. Besifloxacin has broad-spectrum antibacterial activity .

HY-172448

YY2201	ATM/ATR	Cancer
YY2201 is a highly potent and selective ATR inhibitor with an IC₅₀ of 8 nM. YY2201 shows >200-fold more selective for ATR than mTOR. YY2201 inhibits tumor progression in broad-spectrum cancer types (such as lung cancer) .

HY-117857

MRT00033659	Casein Kinase Checkpoint Kinase (Chk) MDM-2/p53 Early 2 Factor (E2F)	Cancer
MRT00033659 is a potent broad-spectrum kinase inhibitor of CK1 (IC₅₀=0.9 μM for CK1δ) and CHK1 (IC₅₀=0.23 μM). MRT00033659, a pyrazolo-pyridine analogue, induces p53 pathway activation and E2F-1 destabilisation .

HY-B1975

Dithianon	Fungal Reactive Oxygen Species (ROS)	Infection
Dithianon is a broad-spectrum anthraquinone fungicide with good adherence to the surface of leaves and fruits. Dithianon is used to control several several fungal of some fruits and vegetables, as anthracnose (*Colletotrichum sp., Elsinoe ampelina), mildew (Plasmopara viticola), phomopsis (Phomopsis viticola*), among others .

HY-B0159A

Balofloxacin dihydrate Q-35 dihydrate	Bacterial Antibiotic	Infection
Balofloxacin dihydrate (Q-35 dihydrate) is an orally active fluoroquinolone antibiotic with broad-spectrum antibacterial activity against gram-negative, gram-positive, and anaerobic bacteria. Balofloxacin dihydrate can be used for the research of respiratory, intestinal, and urinary tract infections .

HY-P3906

Melittin free acid	Fungal Apoptosis Phospholipase Reactive Oxygen Species (ROS)	Infection
Melittin free acid is a basic 26-amino-acid polypeptide, the major active ingredient of honeybee venom. Melittin free acid is an activator of phospholipase A2 (PLA2). Melittin free acid has broad-spectrum antifungal activity with MIC values of 0.4-60 μM. Melittin free acid hinders fungal growth by inducing cell apoptosis, repressing (1,3)-β-D-glucan synthase and participating in other pathways .

HY-136240

Tioxazafen	Parasite	Infection
Tioxazafen is a disubstituted oxadiazole and a broad-spectrum seed treatment nematicide. Tioxazafen is designed to provide consistent broad-spectrum control of nematodes in corn, soy, and cotton .

HY-B2072

Cephaloridine	Antibiotic Bacterial	Infection
Cephaloridine is a broad-spectrum antibacterial antibiotic. Cephaloridine has certain dose-related nephrotoxicity .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-18234A

Leupeptin hemisulfate Maximum Cited Publications 61 Publications Verification	Natural Products Microorganisms Classification of Application Fields Inflammation/Immunology Disease Research Fields Source Classification	Cathepsin Ser/Thr Protease Virus Protease
Leupeptin hemisulfate is a broad-spectrum, membrane-permeable protease inhibitor. Leupeptin hemisulfate potently inhibits serine, cysteine and threonine proteases. Leupeptin hemisulfate inhibits M ^pro (the main protease of SARS-CoV-2) and also has anti-inflammatory activity .

HY-13678

Meropenem 30+ Cited Publications SM 7338	Infection Microorganisms Classification of Application Fields Antibiotics Antibacterial Disease Research Disease Research Fields Beta-lactam Antibiotics Source Classification	Penicillin-binding protein (PBP) Bacterial Antibiotic
Meropenem (SM 7338) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem has activity against susceptible and resistant *N. gonorrhoeae* (MIC value of 0.02-0.06 mg/mL), *H. influenzae* (MIC value of 0.03-0.12 mg/mL), and *H. ducreyi* (MIC value of 0.015-0.12 mg/mL) .

HY-B0474

Tetracycline hydrochloride 50+ Cited Publications	Structural Classification Classification of Application Fields Antibacterial Disease Research Other Antibiotics Plant agriculture research Infection Monophenols Microorganisms Antibiotics Resistance Selection Animal Husbandry Phenols Mammalian Cell Culture Disease Research Fields Source Classification	Environmental Pollutants Antibiotic Bacterial
Tetracycline hydrochloride is a broad-spectrum antibiotic with oral activity. Tetracycline hydrochloride exhibits activity against a wide range of bacteria including gram-positive, gram-negative bacteria, chlamydiae, mycoplasmas and rickettsiae. Tetracycline hydrochloride can be used for the research of infections .

HY-A0107

Tetracycline 50+ Cited Publications	Structural Classification Classification of Application Fields Antibacterial Disease Research Other Antibiotics Plant agriculture research Infection Monophenols Microorganisms Antibiotics Animal Husbandry Phenols Mammalian Cell Culture Disease Research Fields Source Classification	Antibiotic Bacterial
Tetracycline is a broad-spectrum antibiotic with oral activity. Tetracycline exhibits activity against a wide range of bacteria including gram-positive, gram-negative bacteria, chlamydiae, mycoplasmas and rickettsiae. Tetracycline can be used for the research of infections .

HY-B0134

Bestatin 10+ Cited Publications Ubenimex	Infection Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Disease Research Fields Source Classification	Aminopeptidase Bacterial Antibiotic
Bestatin is a natural, broad-spectrum, and competitive CD13 (Aminopeptidase N)/APN and leukotriene A4 hydrolase inhibitor. Bestatin has anticancer effects .

HY-100806

Kynurenic acid 5+ Cited Publications Quinurenic acid	Alkaloids Structural Classification Human Gut Microbiota Metabolites Neurological Disease Classification of Application Fields Quinoline Alkaloids Endogenous metabolite Disease Research Fields Endocrinology	iGluR Endogenous Metabolite Apoptosis CXCR GPR35
Kynurenic acid, an endogenous tryptophan metabolite, is a broad-spectrum antagonist targeting NMDA, glutamate, α7 nicotinic acetylcholine receptor. Kynurenic acid is also an agonist of GPR35/CXCR8.

HY-B0117

Tigecycline 40+ Cited Publications GAR-936	Microorganisms Source Classification	Bacterial Autophagy Antibiotic
Tigecycline (GAR-936) is a broad-spectrum glycylcycline antibiotic. The mean inhibitory concentration (MIC) of Tigecycline for E. coli (MG1655 strain) is approximately 125 ng/mL . MIC₅₀ and MIC₉₀ are 1 and 2 mg/L for Acinetobacter baumannii (A. baumannii), respectively .

HY-B0438

Spectinomycin dihydrochloride 3 Publications Verification	Infection Microorganisms Classification of Application Fields Antibiotics Resistance Selection Mammalian Cell Culture Antibacterial Disease Research Disease Research Fields Other Antibiotics Source Classification	Bacterial Antibiotic
Spectinomycin dihydrochloride is a broad-spectrum antibiotic and inhibits the growth of a variety of gram-positive and gram-negative organisms. Spectinomycin dihydrochloride acts by selectively targeting to the bacterial ribosome and interrupting protein synthesis. Spectinomycin dihydrochloride is also a noncompetitive inhibitor of td intron RNA with an K_i value of 7.2 mM ^- .

HY-N8461

Reuterin 3 Publications Verification 3-Hydroxypropionaldehyde; 3-Hydroxypropanal	Infection Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Disease Research Fields Source Classification	Bacterial
Reuterin is a broad-spectrum antimicrobial agent active against Gram positive and Gram negative bacteria, as well as yeasts, moulds and protozoa. Reuterin is produced by specific strains of Lactobacillus reuteri during anaerobic metabolism of glycerol. Reuterin also demonstrates potent antimicrobial activity against a broad panel of human and poultry meat campylobacter spp. Isolates .

HY-N0372

Licochalcone A 15+ Cited Publications	Chalcones Flavonoids Classification of Application Fields Leguminosae Plants Glycyrrhiza uralensis Fisch. Disease Research Fields Source Classification Cancer	Autophagy
Licochalcone A (LCA), a flavonoid isolated, presents obvious anti-cancer effects, displays broad-spectrum inhibition against UDP-glucuronosyltransferases (UGTs) . Licochalcone A (LCA) exhibits strong inhibitory effects against UGT1A1, 1A3, 1A4, 1A6, 1A7, 1A9, and 2B7 (both IC₅₀ and K_i values lower than 5 μM) .

HY-W017162

DL-3-Phenyllactic acid 2 Publications Verification	Infection Classification of Application Fields Ketones, Aldehydes, Acids Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite Bacterial
DL-3-Phenyllactic acid is a broad-spectrum antimicrobial compound.

HY-B1222

Sisomicin sulfate 5 Publications Verification	Infection Microorganisms Classification of Application Fields Antibiotics Antibacterial Disease Research Disease Research Fields Other Antibiotics Source Classification	Bacterial Antibiotic
Sisomicin sulfate is a broad-spectrum aminoglycoside antibiotic produced by Micromonospora inyoensis. Sisomicin sulfate is highly active against Gram-positive bacteria.

HY-16468

Squalamine 1 Publications Verification MSI-1256; ENT-01 free acid	Infection Triterpenes Animals Classification of Application Fields Terpenoids Marine natural products Other marine organisms Disease Research Fields Cancer	Bacterial HBV FAK Dengue Virus
Squalamine (MSI-1256) is an aminosterol compound with broad-spectrum antiviral activity. Squalamine makes cells less conducive to certain viral replication by altering the electrostatic interactions in the inner membrane of host cells. Squalamine also has antibacterial and antitumor activities. Squalamine has broad-spectrum antibacterial activity against Gram-negative and Gram-positive bacteria, fungi and protozoa. Squalamine inhibits tumor-related angiogenesis and the growth of human breast cancer cells. Squalamine restores the function of enteric nervous system in Parkinson ^,s disease mouse models .

HY-W016420

Fosfomycin sodium 10+ Cited Publications MK-0955 sodium	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Disease Research Fields Source Classification	Bacterial Antibiotic
Fosfomycin (MK-0955) sodium is a blood-brain barrier penetrating, broad-spectrum antibiotic by irreversibly inhibiting an early stage in cell wall synthesis. Fosfomycin sodium shows both in vivo and in vitro activity against a wide range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria .

HY-B0132

Norfloxacin 5 Publications Verification MK-0366	Infection Classification of Application Fields Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Source Classification	Bacterial Endogenous Metabolite Antibiotic
Norfloxacin (MK-0366) is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria, which functions by inhibiting DNA gyrase.

HY-112542

Nemadectin CL-287088; LL-F28249 α	Infection Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Anti-parasitic Disease Research Disease Research Fields Source Classification	Parasite Antibiotic
Nemadectin (CL-287088), an orally active broad-spectrum endectocide, is highly efficacious against natural infections of all the major canine gastrointestinal helminthes. Anthelmintic activity .

HY-107512

Kynurenic acid sodium 5+ Cited Publications	Alkaloids Classification of Application Fields Quinoline Alkaloids Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	iGluR Apoptosis Endogenous Metabolite CXCR GPR35
Kynurenic acid sodium, an endogenous tryptophan metabolite, is a broad-spectrum antagonist targeting NMDA, glutamate, α7 nicotinic acetylcholine receptor. Kynurenic acid sodium is also an agonist of GPR35/CXCR8.

HY-W145518

Pectin	Infection Structural Classification Polysaccharides Malus pumila Mill. Rosaceae Plants Saccharides Source Classification	Environmental Pollutants Antibiotic Endogenous Metabolite Bacterial
Pectin is a heteropolysaccharide, derived from the cell wall of higher plants. Pectin involves in the formation of nanoparticles as a delivery vehicle of agents. Pectin is also an adsorbent, a broad-spectrum antimicrobial agent that binds to bacteria toxins and other irritants in the intestinal mucosa, relieves irritated mucosa .

HY-W018025

5,6-Dihydroxyindole	Natural Products Classification of Application Fields Phenols Polyphenols Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	Bacterial Fungal Parasite Endogenous Metabolite
5,6-Dihydroxyindole, a melanin precursor, has a broad-spectrum antibacterial, antifungal, antiviral, antiparasitic activity. 5,6-Dihydroxyindole has cytotoxic effects and is strongly toxic against various pathogens .

HY-N7112

Leucomycin 1 Publications Verification Kitasamycin	Infection Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Antibacterial Disease Research Disease Research Fields Source Classification	Bacterial Antibiotic
Leucomycin (Kitasamycin) is an orally active macrolide antibiotic produced by Streptomyces kitasatoensis. Leucomycin has broad-spectrum antibacterial activities against gram-positive and gram-negative bacteria, mycoplasma, leptospira, spirochaetes, rickettsiae and some larger viruses .

HY-B0778

Milbemycin oxime 1 Publications Verification	Infection Natural Products Microorganisms Classification of Application Fields Disease Research Fields Source Classification	Antibiotic Parasite
Milbemycin oxime is an orally active macrolide with broad-spectrum antiparasitic activity. Milbemycin oxime is a mixture of oximes consisting of oxime derivatives corresponding to milbemycin A4 and A3. Milbemycin oxime binds to glutamate-gated chloride channels and has inhibitory potency against intestinal nematodes and lung/heart worms .

HY-142127

Ribostamycin 1 Publications Verification Vistamycin; SF-733	Infection Microorganisms Classification of Application Fields Antibiotics Antibacterial Disease Research Disease Research Fields Other Antibiotics Source Classification	Bacterial Antibiotic PDI
Ribostamycin (Vistamycin) is a broad-spectrum aminoglycoside antibiotic. Ribostamycin is effective against Gram-Negative and Gram-Positive bacterial infection. Ribostamycin also inhibits the chaperone activity of PDI .

HY-N7449

Neamine	Infection Cardiovascular Disease Classification of Application Fields Disease Research Fields	Antibiotic Bacterial
Neamine, a degradation product of Neomycin, is a broad-spectrum aminoglycoside antibiotic. Neamine is an anti-angiogenesis agent targeting angiogenin. Neamine has potent antibacterial, antitumor and neuroprotective activities .

HY-W042191

Oxychlororaphine	Natural Products Microorganisms Source Classification	Fungal Apoptosis Caspase Bcl-2 Family MDM-2/p53 PARP
Oxychloroaphine could be isolated from the bacterium Pantoea agglomerans naturally present in soil. Oxychloroaphine has broad-spectrum antifungal activity. Oxychloroaphine has cytotoxicity in a dose-dependent manner and induces apoptosis. Oxychloroaphine can be used in research of cancer .

HY-105088

Pexiganan MSI 78 free base	Infection Structural Classification Natural Products Animals Classification of Application Fields Disease Research Fields Source Classification	Bacterial
Pexiganan (MSI 78) is an orally active antimicrobial peptide with broad-spectrum bactericidal. Pexiganan disrupts bacterial cell membranes, induces peptidoglycan damage and cell lysis. Pexiganan TFA can be used for the research of bacterial infection .

HY-B1828

Spectinomycin	Microorganisms Source Classification	Antibiotic Bacterial
Spectinomycin is a broad-spectrum antibiotic and inhibits the growth of a variety of gram-positive and gram-negative organisms. Spectinomycin acts by selectively targeting to the bacterial ribosome and interrupting protein synthesis. Spectinomycin is also a noncompetitive inhibitor of td intron RNA .

HY-100806R

Kynurenic acid (Standard) 5+ Cited Publications Quinurenic acid (Standard)	Structural Classification Alkaloids Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Quinoline Alkaloids Endogenous metabolite Source Classification	Reference Standards iGluR Endogenous Metabolite Apoptosis CXCR GPR35
Kynurenic acid (Standard) is the analytical standard of Kynurenic acid. This product is intended for research and analytical applications. Kynurenic acid, an endogenous tryptophan metabolite, is a broad-spectrum antagonist targeting NMDA, glutamate, α7 nicotinic acetylcholine receptor. Kynurenic acid is also an agonist of GPR35/CXCR8.

HY-108307

Micronomicin sulfate 1 Publications Verification Gentamicin C2b sulfate; Antibiotic XK-62-2 sulfate; Sagamicin sulfate	Infection Microorganisms Anti-inflammation/Immunoregulatory Antibiotics Antibacterial Disease Research Disease Research Fields Other Antibiotics Source Classification	Antibiotic Bacterial
Micronomicin sulfate (Gentamicin C2b sulfate) is an aminoglycoside antibiotic isolated from Micromonospora. Micronomicin sulfate is a broad-spectrum antibiotic close to the gentamicin-type antibiotics, exhibits a high activity against Pseudomonas, Proteus, Klebsiella pneumoniae, Serratia, etc (MIC=0.001-8.3 μg/ml) .

HY-N1780

3,4-Dimethoxyphenol	Monophenols Microorganisms Classification of Application Fields Phenols Metabolic Disease Cosmetic Research Disease Research Fields Source Classification	Tyrosinase Bacterial
3,4-Dimethoxyphenol is a plant-derived phenylpropanoid compound and can use as a whitening agent in cosmetics. 3,4-Dimethoxyphenol exhibits broad-spectrum antimicrobial activity. 3,4-Dimethoxyphenol has tyrosinase-inhibiting activity. 3,4-Dimethoxyphenol has potent antioxidant effect isolated from the bacterial fermentation broth. 3,4-Dimethoxyphenol can be used for the study of infection .

HY-106681

Lagosin Fungichromin; Pentamycin; Cogomycin	Microorganisms Antifungal Macrolide Antibiotics Classification of Application Fields Antibiotics Disease Research Disease Research Fields Source Classification Cancer	Antibiotic Fungal
Lagosin (Fungichromin) is a polyene macrolide antibiotic. Lagosin has demonstrated broad-spectrum antifungal activity and is impervious to agent resistance .

HY-129034

Ramoplanin	Infection Microorganisms Classification of Application Fields Antibiotics Antibacterial Disease Research Disease Research Fields Other Antibiotics Source Classification	Bacterial Antibiotic
Ramoplanin is a broad-spectrum lipoglycodepsipeptide antibiotic derived from the Actinoplanes spp with with activity against gram-positive bacteria .

HY-B1222A

Sisomicin 5 Publications Verification Antibiotic 6640; Rickamicin	Polysaccharides Microorganisms Saccharides Source Classification	Bacterial Antibiotic
Sisomicin is a broad-spectrum aminoglycoside antibiotic produced by Micromonospora inyoensis. Sisomicin is highly active against Gram-positive bacteria .

HY-113064

Selenocystine 1 Publications Verification	Structural Classification Natural Products Classification of Application Fields Endogenous metabolite Disease Research Fields Source Classification Cancer	Endogenous Metabolite
Selenocystine is a broad-spectrum anti-cancer agent. Selenocystine induces DNA damage in HepG2 cells, particularly in the form of DNA double strand breaks (DSBs). Selenocystine exhibits great promise as a therapeutic or adjuvant agent targeting DNA repair for cancer treatment .

HY-N0275

(±)-10-Hydroxycamptothecin (±)-10-HCPT	Alkaloids Monophenols Pyrrole Alkaloids Classification of Application Fields Phenols Quinoline Alkaloids Camptotheca acuminata Decne. Nyssaceae Plants Disease Research Fields Source Classification Cancer	Topoisomerase
(±)-10-Hydroxycamptothecin is an indole alkaloid that inhibits the activity of topoisomerase I and has a broad spectrum of anticancer activity.

HY-N0306

Hederasaponin B 1 Publications Verification	Infection Triterpenes Hedera nepalensis K. Koch var. sinensis (Tobl.) Rehd. Classification of Application Fields Terpenoids Plants Disease Research Fields Araliaceae Source Classification	Enterovirus
Hederasaponin B, isolated from Hedera helix, has broad-spectrum antiviral activity against various subgenotypes of Enterovirus 71 (EV71).

HY-108016

Peruvoside Encordin	Apocynaceae Triterpenes Terpenoids Thevetia peruviana (Pers.) K. Schum. Plants Source Classification	Src PI3K JNK STAT EGFR Apoptosis Autophagy
Peruvoside is a potent inhibitor of Src, PI3K, JNK, STAT, and EGFR. Peruvoside induces apoptosis and autophagy and possesses a broad spectrum of anticancer activity in breast, lung, liver cancers and leukemia. Peruvoside is a broad-spectrum and potent antiviral activity against positive-sense RNA viruses. Peruvoside sensitizes Gefitinib (HY-50895)-resistant tumour cells (A549, PC9/gef and H1975) to Gefitinib .

HY-A0107R

Tetracycline (Standard)	Structural Classification Monophenols Microorganisms Antibiotics Animal Husbandry Phenols Mammalian Cell Culture Antibacterial Disease Research Other Antibiotics Plant agriculture research Source Classification	Reference Standards Bacterial Antibiotic
Tetracycline (Standard) is the analytical standard of Tetracycline. This product is intended for research and analytical applications. Tetracycline is a broad-spectrum antibiotic with oral activity. Tetracycline exhibits activity against a wide range of bacteria including gram-positive, gram-negative bacteria, chlamydiae, mycoplasmas and rickettsiae. Tetracycline can be used for the research of infections .

HY-N7111

Sultamicillin tosylate Sultamicillin (tosilate)	Infection Classification of Application Fields Disease Research Fields	Bacterial Antibiotic
Sultamicillin tosylate is a broad-spectrum and orally active beta-lactamase inhibitor, an antibiotic with antibacterial activity .

HY-B0474R

Tetracycline hydrochloride (Standard)	Structural Classification Antibacterial Disease Research Other Antibiotics Plant agriculture research Monophenols Microorganisms Antibiotics Resistance Selection Animal Husbandry Phenols Mammalian Cell Culture Source Classification	Reference Standards Bacterial Antibiotic
Tetracycline (hydrochloride) (Standard) is the analytical standard of Tetracycline (hydrochloride). This product is intended for research and analytical applications. Tetracycline (hydrochloride) is a broad-spectrum antibiotic, exhibiting activity against a wide range of gram-positive and gram-negative bacteria.

HY-B0132R

Norfloxacin (Standard) MK-0366 (Standard)	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Bacterial Endogenous Metabolite Antibiotic
Norfloxacin (Standard) is the analytical standard of Norfloxacin. This product is intended for research and analytical applications. Norfloxacin (MK-0366) is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria, which functions by inhibiting DNA gyrase.

HY-B1222R

Sisomicin sulfate (Standard)	Structural Classification Microorganisms Antibiotics Antibacterial Disease Research Other Antibiotics Source Classification	Reference Standards Bacterial Antibiotic
Sisomicin (sulfate) (Standard) is the analytical standard of Sisomicin (sulfate). This product is intended for research and analytical applications. Sisomicin sulfate is a broad-spectrum aminoglycoside antibiotic produced by Micromonospora inyoensis. Sisomicin sulfate is highly active against Gram-positive bacteria [4].

HY-118448

2,4-Diacetylphloroglucinol	Microorganisms Source Classification	Antibiotic Bacterial Fungal Parasite
2,4-Diacetylphloroglucinol is a polyketide antibiotic produced by Pseudomonas fluorescens. 2,4-Diacetylphloroglucinol exhibits broad-spectrum toxicity against various organisms such as bacteria, fungi, oomycetes, and nematodes. 2,4-Diacetylphloroglucinol can also inhibit plant pathogens and affect the root development of tomato seedlings .

HY-N11857

Gentamicin C2	Structural Classification Microorganisms Antibiotics Source Classification	Antibiotic Bacterial
Gentamicin C2 is an aminoglycoside antibiotic with broad-spectrum bactericidal activity, selectively binding to the bacterial 16S rRNA A-site. Gentamicin C2 interferes with protein synthesis initiation and translation fidelity to exert bactericidal effects. Gentamicin C2 can be used for the research of bacterial infections .

HY-B0956A

Paromomycin Aminosidine	Structural Classification Microorganisms Antibiotics Other Antibiotics Source Classification	Bacterial Parasite Endogenous Metabolite
Paromomycin (Aminosidine) is an orally active broad-spectrum aminoglycoside aminocyclitol. Paromomycin is produced by Streptomyces riomosus var. Paromomycinus. Paromomycin binding induces local conformational changes in the 16S rRNA A-site. Paromomycin exhibits inhibitory activity against C. parvum. Paromomycin can be used in research related to leishmaniasis, amoebiasis and cryptosporidiosis .

HY-76200R

Voriconazole (Standard) UK-109496 (Standard)	Microorganisms Source Classification	Reference Standards Fungal Bacterial
Voriconazole (Standard) is the analytical standard of Voriconazole. This product is intended for research and analytical applications. Voriconazole (UK-109496) is a second-generation, broad-spectrum triazole antifungal agent that inhibits fungal ergosterol biosynthesis. Voriconazole exerts its antifungal activity by inhibition of 14-α-lanosterol demethylation, which is mediated by fungal cytochrome P450 enzymes .

HY-129972

Ribavirin 5'-monophosphate dilithium RMP dilithium	Structural Classification Natural Products Endogenous metabolite Source Classification	Nucleoside Antimetabolite/Analog
Ribavirin 5'-monophosphate dilithium is an active form of ribavirin that inhibits IMP dehydrogenase, and ribavirin itself is a broad-spectrum antiviral agent .

HY-N6737

Aureothricin	Infection Microorganisms Classification of Application Fields Antibiotics Antibacterial Disease Research Disease Research Fields Other Antibiotics Source Classification	Bacterial Antibiotic
Aureothricin is a dithiolopyrrolone (DTP) antibiotic first isolated from Streptomyces and exhibits relatively broad-spectrum antibiotic activity. Aureothricin can inhibit adhesion of human umbilical vein endothelial cells (HUVECs) to vitronectin .

HY-W017162R

DL-3-Phenyllactic acid (Standard)	Structural Classification Ketones, Aldehydes, Acids Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite Bacterial
DL-3-Phenyllactic acid (Standard) is the analytical standard of DL-3-Phenyllactic acid. This product is intended for research and analytical applications. DL-3-Phenyllactic acid is a broad-spectrum antimicrobial compound.

HY-111903

Levomecol	Infection Plant Cell Culture Microorganisms Classification of Application Fields Antibiotics Antibacterial Disease Research Disease Research Fields Other Antibiotics Source Classification	Bacterial
Levomecol (Chloramphenicol), made up of Chloramphenicol, Methyluracil, is a broad-spectrum antibiotic that is derived from the bacterium Streptomyces venezuelae. Levomecol (Chloramphenicol)) stops bacterial growth by binding to the bacterial ribosome (blocking peptidyl transferase) and inhibiting protein synthesis .

HY-N12697A

Polycarpine hydrochloride	Alkaloids Animals Other Alkaloids Source Classification	SARS-CoV Virus Protease Influenza Virus Fungal
Polycarpine hydrochloride (1a) is a broad-spectrum Mpro inhibitor (IC₅₀ = 30 nM) that can be isolated from the Polycarpa aurata and also serves as an anti-coronaviral agent. Polycarpine hydrochloride possesses antiviral and antifungal activities, with IC₅₀ values of 30.0 nM and 0.12 μM against SARS-CoV-2 Mpro and PEDV Mpro, respectively .

Cat. No.	Product Name	Chemical Structure

HY-100806S

Kynurenic acid-d5 1 Publications Verification
Kynurenic acid-d₅ is the deuterium labeled Kynurenic acid. Kynurenic acid, an endogenous tryptophan metabolite, is a broad-spectrum antagonist targeting NMDA, glutamate, α7 nicotinic acetylcholine receptor. Kynurenic acid is also an agonist of GPR35/CXCR8 .

HY-13678S

Meropenem-d6
Meropenem-d₆ is the deuterium labeled Meropenem. Meropenem (SM 7338) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL) .

HY-A0107S

Tetracycline-d6
Tetracycline-d₆ is the deuterium labeled Tetracycline. Tetracycline is a broad-spectrum antibiotic, exhibiting activity against a wide range of gram-positive and gram-negative bacteria.

HY-B0467S

Amoxicillin-d4
Amoxicillin-d₄ is a deuterium labeled Amoxicillin. Amoxicillin is an antibiotic with good oral absorption and broad spectrum antimicrobial activity .

HY-B0239S

Chloramphenicol-d5
Chloramphenicol-d₅ is the deuterium labeled Chloramphenicol. Chloramphenicol is a broad-spectrum antibiotic against bacterial infections .

HY-16980S

Eravacycline-d4 dihydrochloride
Eravacycline-d₄ (TP-434-d₄) dihydrochloride is deuterium labeled Eravacycline. Eravacycline is a potent and broad-spectrum antibacterial agent .

HY-B0522S

Ampicillin-d5
Ampicillin-d₅ is the deuterium labeled Ampicillin. Ampicillin is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria .

HY-76200S

Voriconazole-d3 2 Publications Verification
Voriconazole-d₃ is the deuterium labeled Voriconazole. Voriconazole (UK-109496) is a second-generation, broad-spectrum triazole antifungal agent that inhibits fungal ergosterol biosynthesis. Voriconazole exerts its antifungal activity by inhibition of 14-α-lanosterol demethylation, which is mediated by fungal cytochrome P450 enzymes .

HY-B0479S

Thiamphenicol-d3
Thiamphenicol-d₃ is a deuterium labeled Thiamphenicol. Thiamphenicol, a methyl-sulfonyl derivative of Chloramphenicol, is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit, leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative, Gram-positive aerobic and anaerobic bacteria) .

HY-17373S1

Posaconazole-d4 1 Publications Verification
Posaconazole-d₄ is a deuterium-labeled form of Posaconazole. Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity .

HY-B0394S

Atropine-d5
Atropine-d₅ is the deuterium labeled Atropine (sulfate monohydrate). Atropine (Tropine tropate) sulfate monohydrate is a broad-spectrum and competitive muscarinic acetylcholine receptor (mAChR) antagonist with anti-myopia effect .

HY-B0132S

Norfloxacin-d5
Norfloxacin-d₅ is the deuterium labeled Norfloxacin. Norfloxacin is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria, which functions by inhibiting DNA gyrase .

HY-W747676

Glyphosate-13C

Glyphosate- ¹³C is the ¹³C-labeled Glyphosate (HY-B0863). Glyphosate, a non-selective systemic biocide with broad-spectrum activity, is an herbicidal derivative of the amino acid glycine. Glyphosate inhibits the enzymatic activity of the 5-endopyruvylshikimate 3-phosphate synthase (EPSPS) in the shikimic acid pathway, preventing the synthesis of the aromatic amino acids tyrosine, phenylalanine, and tryptophan. Glyphosate induces oxidative stress, neuroinflammation, and mitochondrial dysfunction, processes that lead to neuronal death by autophagia, necrosis, or apoptosis, as well as the appearance of behavioral and motor disorders .

HY-143831S

Cefepime-d8 sulfate

Cefepime-d₈ (BMY-28142-d₈) sulfate is deuterium labeled Cefepime sulfate. Cefepime sulfate is a broad-spectrum, blood-brain barrier-permeable cephalosporin antibiotic with hPON1 inhibitory activity, with an IC₅₀ of 21.115 mM and a K_i of 35.092 mM. Cefepime sulfate inhibits hPON1 via a non-competitive mechanism and blocks GABA_A receptors. Cefepime sulfate penetrates the outer membrane of Gram-negative bacteria, inhibits the growth of Gram-positive and Gram-negative bacteria, and does not induce the production of β-lactamase.

HY-B0272S2

Rifampicin-d4
Rifampicin-d₄ is the deuterium labeled Rifampicin. Rifampicin is a potent and broad spectrum antibiotic against bacterial pathogens. Rifampicin has anti-influenza virus activities.

HY-W017162S

DL-3-Phenyllactic acid-d3
DL-3-Phenyllactic acid-d3 is a deuterated labeled DL-3-Phenyllactic acid . DL-3-Phenyllactic acid is a broad-spectrum antimicrobial compound.

HY-B0117S

Tigecycline-d9
Tigecycline-d₉ is deuterium labeled Tigecycline. Tigecycline (GAR-936) is a broad-spectrum glycylcycline antibiotic. The mean inhibitory concentration (MIC) of Tigecycline for E. coli (MG1655 strain) is approximately 125 ng/mL . MIC₅₀ and MIC90 are 1 and 2 mg/L for Acinetobacter baumannii (A. baumannii), respectively .

HY-W654100

Cefepime-d3 sulfate

Cefepime-d₃ (BMY-28142-d₃) sulfate is deuterium labeled Cefepime sulfate. Cefepime sulfate is a broad-spectrum, blood-brain barrier-permeable cephalosporin antibiotic with hPON1 inhibitory activity, with an IC₅₀ of 21.115 mM and a K_i of 35.092 mM. Cefepime sulfate inhibits hPON1 via a non-competitive mechanism and blocks GABA_A receptors. Cefepime sulfate penetrates the outer membrane of Gram-negative bacteria, inhibits the growth of Gram-positive and Gram-negative bacteria, and does not induce the production of β-lactamase.

HY-B1145S

Chlorhexidine-d8 dihydrochloride

Chlorhexidine-d₈ (dihydrochloride) is the deuterium labeled Chlorhexidine dihydrochloride (HY-B1145). Chlorhexidine dihydrochloride is a orally active cationic antimicrobial agent that targets microbial cell membranes. Chlorhexidine dihydrochloride binds to cell membrane phospholipids non-specifically, destroys membrane structure and induces leakage of cell contents. Chlorhexidine dihydrochloride has broad-spectrum bactericidal activity against both Gram-positive and Gram-negative bacteria. Chlorhexidine dihydrochloride can interfere with membrane permeability, cause protein precipitation and energy metabolism disorders, such as rapid inhibition of microbial growth and induction of cell death (necrosis or apoptosis) .

HY-17373S

Posaconazole-d5
Posaconazole-d₅ is a deuterium-labeled form of Posaconazole. Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity .

HY-W015026S

Isobutylparaben-d4
Isobutylparaben-d₄ is the deuterium labeled Isobutylparaben. Isobutylparaben (Isobutyl 4-hydroxybenzoate) is the agonist for PXR, CAR and PPAR. Isobutylparaben has a broad-spectrum antimicrobial activity and widely used in personal care products and cosmetics .

HY-W654101

Cefotaxime-d3
Cefotaxime-d3 is the deuterium labeled Cefotaxime (HY-A0088A). Cefotaxime is the β-lactamase stable cephalosporin and the third-generation cephalosporin antibiotic. Cefotaxime possesses broad-spectrum antibiotic activity against numerous Gram-positive and Gram-negative bacteria .

HY-A0090S

Nitrofurantoin-13C3
Nitrofurantoin- ¹³C₃ is the ¹³C labeled Nitrofurantoin (HY-A0090) . Nitrofurantoin is a potent and orally active broad-spectrum beta-lactamase antimicrobial agent. Nitrofurantoin acts as an antibiotic and can be used for the study of urinary tract infections (UTIs), including cystitis and kidney infections .

HY-14956S

Nemonoxacin-d3

Nemonoxacin-d₃ is the deuterium labeled Nemonoxacin. Nemonoxacin (TG-873870) is an orally active and potent broad-spectrum antibiotic. Nemonoxacin shows good inhibitory activity against different species of staphylococci, streptococci, and enterococci, Neisseria gonorrhoeae, and Haemophilus influenza. Nemonoxacin can be used in the study of bacterial infections and community-acquired pneumonia .

HY-B0831S

Buprofezin-d6

Buprofezin-d₆ is the deuterium labeled Buprofezin. Buprofezin is a broad-spectrum insecticide and chitin synthesis inhibitor that targets developmental stage coleopteran pests.Buprofezin promotes the conversion of energy metabolism from the aerobic tricarboxylic acid (TCA) cycle and oxidative phosphorylation to anaerobic glycolysis. Buprofezin also promotes the production of reactive oxygen species (ROS) by inhibiting cytochrome c oxidase .

HY-B0122S

Topiramate-13C6

Topiramate-13C6 (McN 4853-13C6) is the ¹³C labeled isotope of Topiramate (HY-B0122). Topiramate (McN 4853) is a broad-spectrum antiepileptic agent. Topiramate is a GluR5 receptor antagonist. Topiramate produces its antiepileptic effects through enhancement of GABAergic activity, inhibition of kainate/AMPA receptors, inhibition of voltage-sensitive sodium and calcium channels, increases in potassium conductance, and inhibition of carbonic anhydrase .

HY-B0210S

Cefoperazone-d5
Cefoperazone-d₅ is deuterium labeled Cefoperazone. Cefoperazone, a semisynthetic cephalosporin, has a broad spectrum of antibacterial activity .

HY-B1414S

Chloroxylenol-d6
Chloroxylenol-d₆ is the deuterium labeled Chloroxylenol. Chloroxylenol is a broad spectrum antimicrobial chemical compound used to control bacteria, algae, fungi and virus.

HY-136382S

Sulfachloropyridazine-d4
Sulfachloropyridazine-d₄ is the deuterium labeled Sulfachloropyridazine. Sulfachloropyridazine is a broad spectrum sulfonamide used against both Gram-positive and Gram-negative aerobic bacteria .

HY-12785S

Albendazole sulfoxide D3
Albendazole sulfoxide-d₃ is deuterium labeled Albendazole sulfoxide, which is a broad-spectrum anthelmintic.

HY-14814S

Delafloxacin-d5
Delafloxacin-d₅ is deuterium labeled Delafloxacin. Delafloxacin (RX-3341; WQ-3034; ABT492) is a broad-spectrum fluoroquinolone antibiotic. Delafloxacin has a broad spectrum of activity that includes drug-resistant Staphylococcus aureus, Streptococcus pneumoniae, and Klebsiella pneumonia .

HY-B0223S2

Albendazole-d7
Albendazole-d₇ is the deuterium labeled Albendazole. Albendazole is a broad-spectrum parasiticide with high effectiveness and low host toxicity. Albendazole is used for the research gastrointestinal parasites in humans and animals .

HY-N0168S

Hesperetin-d3
Hesperetin-d₃ is the deuterium labeled Hesperetin . Hesperetin is a natural flavanone, and acts as a potent and broad-spectrum inhibitor against human UGT activity. Hesperetin regulates apoptosis .

HY-A0088S

Cefotaxime-d3 sodium
Cefotaxime-d₃ (sodium) is the deuterium labeled Cefotaxime (sodium salt). Cefotaxime sodium salt, a β-lactamase stable cephalosporin and a third-generation cephalosporin antibiotic, possesses broad-spectrum antibiotic activity against numerous Gram-positive and Gram-negative bacteria .

HY-15287S1

Nelfinavir-d4
Nelfinavir-d₄ is deuterated labeled Nelfinavir (HY-15287). Nelfinavir (AG-1341) is a potent and orally bioavailable HIV-1 protease inhibitor (K_i=2 nM) for HIV infection. Nelfinavir is a broad-spectrum, anticancer agent .

HY-B0239S3

Chloramphenicol-d4
Chloramphenicol-d₄ is deuterium labeled Chloramphenicol. Chloramphenicol, a broad-spectrum antibiotic, acts as a potent inhibitor of bacterial protein biosynthesis . Chloramphenicol acts primarily on the 50S subunit of bacterial 70S rihosomes and inhibits peptide bond formation by suppressing peptidyl transferase activity .

HY-14283S1

Luliconazole-d3
Luliconazole-d₃ (NND 502-d₃) is deuterium labeled Luliconazole. Luliconazole (NND 502)?is a topical antifungal imidazole antibiotic with broad-spectrum and potent antifungal activity. Luliconazole can be used for the research of skin infection, including?dermatophytosis, tinea corporis, tinea pedis?et al .

HY-B1075AS

(Rac)-Fosfomycin (benzylamine)-13C3

(Rac)-Fosfomycin (benzylamine)- ¹³C₃ is the ¹³C labeled Fosfomycin . Fosfomycin (MK-0955) is a broad-spectrum antibiotic. Fosfomycin can cross blood-brain barrier penetrating, and irreversibly inhibits an early stage in cell wall synthesis. Fosfomycin shows anti-bacteria activity for a range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria .

HY-B0467AS

Amoxicillin-13C6
Amoxicillin- ¹³C₆ is the ¹³C₆ labeled Amoxicillin. Amoxicillin is an antibiotic with good oral absorption and broad spectrum antimicrobial activity.

HY-B1190S

Cefadroxil-d4 hydrate

Cefadroxil-d₄ (hydrate) is the deuterium labeled Cefadroxil hydrate (HY-B1190A). Cefadroxil hydrate is an orally active broad-spectrum cephalosporin antibiotic. Cefadroxil hydrate inhibits bacterial cell wall synthesis and enhances the expression of glutamate transporter-1. Cefadroxil hydrate is dependent on the intestinal peptide transporter PepT1 for small intestinal absorption. Cefadroxil hydrate has inhibitory and bactericidal activity against a variety of Gram-positive and Gram-negative bacteria and has analgesic effects on neuropathic pain .

HY-B0239S2

Threo-Chloramphenicol-d6

Threo-Chloramphenicol-d₆ is the deuterium labeled Chloramphenicol . Chloramphenicol is an orally active, potent and broad-spectrum antibiotic. Chloramphenicol shows antibacterial activity. Chloramphenicol represses the oxygen-labile transcription factor and hypoxia inducible factor-1 alpha (HIF-1α) in hypoxic A549 and H1299 cells. Chloramphenicol suppresses the mRNA levels of vascular endothelial growth factor (VEGF) and glucose transporter 1, eventually decreasing VEGF release. Chloramphenicol can be used for anaerobic infections and lung cancer research .

HY-A0269S

Mecillinam-d12
Mecillinam-d₁₂ is deuterium labeled Mecillinam. Mecillinam (Amdinocillin), the β-lactam antibiotic, has a broad spectrum of activity against gram-negative organisms .

HY-B0272S

Rifampicin-d3
Rifampicin-d₃ is the deuterium labeled Rifampicin. Rifampicin is a potent and broad spectrum antibiotic against bacterial pathogens. Rifampicin has anti-influenza virus activities .

HY-B0434S

Ribavirin-13C5
Ribavirin- ¹³C₅ is the ¹³C-labeled Ribavirin. Ribavirin (ICN-1229) is an antiviral agent against a broad spectrum of viruses including HCV, HIVl, and RSV.

HY-135393S

Sulfadimethoxypyrimidine-d4
Sulfadimethoxypyrimidine-d₄ is a deuterium labeled Sulfadimethoxypyrimidine. Sulfadimethoxypyrimidine is a sulfonamide antibiotic with a broad-spectrum antibacterial effect .

HY-B1790S

Terconazole-d4
Terconazole-d₄ is the deuterium labeled Terconazole. Terconazole is a broad-spectrum antifungal medication for the treatment of vaginal yeast infection.

HY-W706112

Chloramphenicol-d5-2
Chloramphenicol-d₅-2 is the deuterium labeled Chloramphenicol (HY-B0239). Chloramphenicol is an orally active, potent and broad-spectrum antibiotic .

HY-115364S

Parbendazole-d3
Parbendazole-d₃ is the deuterium labeled Parbendazole. Parbendazole is a potent inhibitor of microtubule assembly, destabilizes tubulin, with an EC50 of 530 nM, and exhibits a broad-spectrum anthelmintic activity.

HY-114750S

Mebendazole-amine-13C6
Mebendazole-amine- ¹³C₆ is the ¹³C₆ labeled Mebendazole-amine. Mebendazole-amine is a metabolite of Mebendazole. Mebendazole is a broad-spectrum benzimidazole anti-helminthic agent.

HY-17373S3

Posaconazole-d7
Posaconazole-d₇ (SCH 56592-d₇) is deuterium labeled Posaconazole. Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity.

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-12318G

IBMX 3-Isobutyl-1-methylxanthine; Isobutylmethylxanthine	Phosphodiesterase (PDE)	Inflammation/Immunology
IBMX (3-Isobutyl-1-methylxanthine) (GMP) is IBMX (HY-12318) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. IBMX is a broad-spectrum phosphodiesterase (PDE) inhibitor .

HY-15764G

A 419259 RK-20449	Src Apoptosis	Cancer
A 419259 GMP is the GMP grade A 419259 (HY-15764), inducing cell apoptosis. GMP-grade small molecules can be used as auxiliary reagents in cell therapy. A 419259 (RK-20449) is a broad-spectrum pyrrole-pyrimidine inhibitor targeting Src, Lck, and Lyn with IC₅₀s of 9 nM, <3 nM, and <3 nM, respectively .

HY-B0434G

Ribavirin Ribasphere; ICN-1229	Antibiotic RSV HCV Orthopoxvirus	Infection
Ribavirin (GMP) is Ribavirin (HY-B0434) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Ribavirin (ICN-1229) is an antiviral agent against a broad spectrum of viruses including HCV, HIVl, and RSV. Ribavirin also has anti-orthopoxvirus and anti-variola activities.

HY-B0450AG

Ciclopirox olamine Ciclopirox ethanolamine; HOE 296	Bacterial Fungal Ferroptosis	Infection
Ciclopirox (olamine) (GMP) is Ciclopirox olamine (HY-B0450A) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Ciclopirox (HOE296b) is a synthetic antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic .

HY-N0565AG

Doxycycline (hydrochloride)	Apoptosis MMP Akt PI3K	Infection Neurological Disease Inflammation/Immunology Cancer
Doxycycline hydrochloride GMP is Doxycycline (hydrochloride) (HY-N0565A) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Doxycycline hydrochloride is an orally active highly lipophilic, tissue-permeable MMP inhibitor with broad-spectrum antibacterial activity. Doxycycline hydrochloride is also a semi-synthetic antibiotic with chelating properties, which blocks bacterial protein synthesis and inhibits extracellular matrix degradation through interactions with zinc and calcium atoms. Doxycycline hydrochloride also inhibits mitochondrial biogenesis, translation, and the expression of respiratory chain proteins. Doxycycline hydrochloride induces apoptosis, inhibits autophagy and EMT, downregulates stem cell markers, and activates the PI3K-AKT pathway, thereby effectively inhibiting the viability and proliferation of cancer cells such as breast cancer cells. Doxycycline hydrochloride also promotes the survival and self-renewal of embryonic stem cells and neural stem cells, and reduces the frequency of medium changes in culture. Doxycycline hydrochloride has been applied in studies related to breast cancer, prostate cancer, bladder cancer, and other cancers .

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